(5 nodes) Translation initiation factor binding, and SUI1 domain network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd4_3770	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1040 aa)
	cgd5_390	Putative eukaryotic translation initiation factor 3. (1030 aa)
	cgd2_820	Putative translation initiation factor 1 (eIF1), SUI1p. (112 aa)
	cgd8_3330	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (143 aa)
	cgd7_2430	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains. (460 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cgd2_820	cgd4_3770	Q5CU04	Q5CQQ0	Putative translation initiation factor 1 (eIF1), SUI1p.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
cgd2_820	cgd5_390	Q5CU04	Q5CS35	Putative translation initiation factor 1 (eIF1), SUI1p.	Putative eukaryotic translation initiation factor 3.	0.986
cgd2_820	cgd7_2430	Q5CU04	Q5CYG4	Putative translation initiation factor 1 (eIF1), SUI1p.	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	0.987
cgd2_820	cgd8_3330	Q5CU04	Q5CVP1	Putative translation initiation factor 1 (eIF1), SUI1p.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.999
cgd4_3770	cgd2_820	Q5CQQ0	Q5CU04	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative translation initiation factor 1 (eIF1), SUI1p.	0.999
cgd4_3770	cgd5_390	Q5CQQ0	Q5CS35	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative eukaryotic translation initiation factor 3.	0.998
cgd4_3770	cgd7_2430	Q5CQQ0	Q5CYG4	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	0.999
cgd4_3770	cgd8_3330	Q5CQQ0	Q5CVP1	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.999
cgd5_390	cgd2_820	Q5CS35	Q5CU04	Putative eukaryotic translation initiation factor 3.	Putative translation initiation factor 1 (eIF1), SUI1p.	0.986
cgd5_390	cgd4_3770	Q5CS35	Q5CQQ0	Putative eukaryotic translation initiation factor 3.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.998
cgd5_390	cgd7_2430	Q5CS35	Q5CYG4	Putative eukaryotic translation initiation factor 3.	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	0.996
cgd5_390	cgd8_3330	Q5CS35	Q5CVP1	Putative eukaryotic translation initiation factor 3.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.993
cgd7_2430	cgd2_820	Q5CYG4	Q5CU04	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	Putative translation initiation factor 1 (eIF1), SUI1p.	0.987
cgd7_2430	cgd4_3770	Q5CYG4	Q5CQQ0	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
cgd7_2430	cgd5_390	Q5CYG4	Q5CS35	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	Putative eukaryotic translation initiation factor 3.	0.996
cgd7_2430	cgd8_3330	Q5CYG4	Q5CVP1	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.994
cgd8_3330	cgd2_820	Q5CVP1	Q5CU04	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Putative translation initiation factor 1 (eIF1), SUI1p.	0.999
cgd8_3330	cgd4_3770	Q5CVP1	Q5CQQ0	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
cgd8_3330	cgd5_390	Q5CVP1	Q5CS35	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Putative eukaryotic translation initiation factor 3.	0.993
cgd8_3330	cgd7_2430	Q5CVP1	Q5CYG4	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains.	0.994