(16 nodes) Processing of Intronless Pre-mRNAs, and Set1C/COMPASS complex network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd8_3960	WD_REPEATS_REGION domain-containing protein. (316 aa)
	cgd8_460	Cleavage and polyadenylation specifity factor protein, CPSF metallobeta-lactamase. (780 aa)
	Pap1p	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (699 aa)
	cgd4_820	WD repeat protein. (737 aa)
	cgd5_2880	C1p1p GTpase. Pre-mRNA cleavaage complex protein. (601 aa)
	cgd5_1070	CCCH RNA binding domain involved in RNA metabolism. (253 aa)
	cgd5_510	Symplekin_C domain-containing protein. (1720 aa)
	cgd1_3160	mRNA 3' end processing protein RNA14, HAT repeats. (1452 aa)
	cgd1_1310	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain. (304 aa)
	cgd8_4770	CPSF_A domain-containing protein. (1965 aa)
	cgd8_3720	D441/Mpe1p like protein with a zinc knuckle (C2HC) and PhD Zn finger domain. (475 aa)
	cgd6_3810	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (277 aa)
	cgd6_1730	Cleavage and polyadenylation specificity factor 4-like 3x Zn C3H1 domains. (178 aa)
	cgd6_580	Cleavage and polyadenylation specificity factor subunit 2. (1196 aa)
	cgd6_400	Pre-mRNA polyadenylation factor. (327 aa)
	cgd7_4140	WD40 domain protein. (408 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pap1p	cgd1_1310	Q5CQF4	Q5CSU2	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	0.978
Pap1p	cgd1_3160	Q5CQF4	Q5CSD5	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	mRNA 3' end processing protein RNA14, HAT repeats.	0.987
Pap1p	cgd4_820	Q5CQF4	Q5CQG4	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	WD repeat protein.	0.845
Pap1p	cgd5_1070	Q5CQF4	Q5CRX8	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	CCCH RNA binding domain involved in RNA metabolism.	0.895
Pap1p	cgd5_2880	Q5CQF4	Q5CRG2	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	C1p1p GTpase. Pre-mRNA cleavaage complex protein.	0.861
Pap1p	cgd5_510	Q5CQF4	Q5CS25	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Symplekin_C domain-containing protein.	0.998
Pap1p	cgd6_1730	Q5CQF4	Q5CXB5	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Cleavage and polyadenylation specificity factor 4-like 3x Zn C3H1 domains.	0.999
Pap1p	cgd6_3810	Q5CQF4	Q5CWT4	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.857
Pap1p	cgd6_400	Q5CQF4	Q5CXN1	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Pre-mRNA polyadenylation factor.	0.999
Pap1p	cgd6_580	Q5CQF4	Q5CXL4	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Cleavage and polyadenylation specificity factor subunit 2.	0.999
Pap1p	cgd7_4140	Q5CQF4	Q5CY10	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	WD40 domain protein.	0.996
Pap1p	cgd8_3720	Q5CQF4	Q5CVK5	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	D441/Mpe1p like protein with a zinc knuckle (C2HC) and PhD Zn finger domain.	0.990
Pap1p	cgd8_3960	Q5CQF4	A3FPZ8	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	WD_REPEATS_REGION domain-containing protein.	0.987
Pap1p	cgd8_460	Q5CQF4	Q5CPX2	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	Cleavage and polyadenylation specifity factor protein, CPSF metallobeta-lactamase.	0.997
Pap1p	cgd8_4770	Q5CQF4	Q5CVA8	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	CPSF_A domain-containing protein.	0.998
cgd1_1310	Pap1p	Q5CSU2	Q5CQF4	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.978
cgd1_1310	cgd1_3160	Q5CSU2	Q5CSD5	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	mRNA 3' end processing protein RNA14, HAT repeats.	0.999
cgd1_1310	cgd4_820	Q5CSU2	Q5CQG4	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	WD repeat protein.	0.998
cgd1_1310	cgd5_1070	Q5CSU2	Q5CRX8	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	CCCH RNA binding domain involved in RNA metabolism.	0.888
cgd1_1310	cgd5_2880	Q5CSU2	Q5CRG2	Cleavage stimulation factor subunit 2 that has a CSF1 like RRM domain.	C1p1p GTpase. Pre-mRNA cleavaage complex protein.	0.950