(10 nodes) Phosphatidylinositol phosphate biosynthetic process, and Inositol phosphate metabolism network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd8_3280	Phosphatidylinositol-4-phosphate 5-kinase, putative. (828 aa)
	cgd2_1810	CysQ, sulfite synthesis pathway protein, putative. (314 aa)
	cgd4_80	Sac1p family protein. (836 aa)
	cgd4_2560	Phosphoinositide phospholipase C. (883 aa)
	cgd2_1910	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein. (534 aa)
	cgd2_1340	Possible phosphatidylinositol 3-and 4-kinase family protein. (678 aa)
	cgd8_4500	Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family. (1114 aa)
	cgd6_3570	Myotubularin related protein 1, C-terminus protein tyrosine/serine phosphatase, catalytic domain. (910 aa)
	cgd6_3390	Phosphatidylinositol 4-kinase A; Belongs to the PI3/PI4-kinase family. (2158 aa)
	cgd7_1500	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1014 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cgd2_1340	cgd2_1910	Q5CTW1	Q5CTR8	Possible phosphatidylinositol 3-and 4-kinase family protein.	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	0.565
cgd2_1340	cgd4_80	Q5CTW1	Q5CQN0	Possible phosphatidylinositol 3-and 4-kinase family protein.	Sac1p family protein.	0.564
cgd2_1340	cgd6_3390	Q5CTW1	Q5CWX0	Possible phosphatidylinositol 3-and 4-kinase family protein.	Phosphatidylinositol 4-kinase A; Belongs to the PI3/PI4-kinase family.	0.794
cgd2_1340	cgd8_3280	Q5CTW1	A3FPZ4	Possible phosphatidylinositol 3-and 4-kinase family protein.	Phosphatidylinositol-4-phosphate 5-kinase, putative.	0.565
cgd2_1340	cgd8_4500	Q5CTW1	Q5CVD3	Possible phosphatidylinositol 3-and 4-kinase family protein.	Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.	0.763
cgd2_1810	cgd7_1500	A3FQ70	Q5CYP7	CysQ, sulfite synthesis pathway protein, putative.	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	0.665
cgd2_1910	cgd2_1340	Q5CTR8	Q5CTW1	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	Possible phosphatidylinositol 3-and 4-kinase family protein.	0.565
cgd2_1910	cgd4_2560	Q5CTR8	Q5CR08	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	Phosphoinositide phospholipase C.	0.691
cgd2_1910	cgd4_80	Q5CTR8	Q5CQN0	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	Sac1p family protein.	0.495
cgd2_1910	cgd6_3390	Q5CTR8	Q5CWX0	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	Phosphatidylinositol 4-kinase A; Belongs to the PI3/PI4-kinase family.	0.735
cgd2_1910	cgd8_4500	Q5CTR8	Q5CVD3	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.	0.782
cgd4_2560	cgd2_1910	Q5CR08	Q5CTR8	Phosphoinositide phospholipase C.	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	0.691
cgd4_2560	cgd4_80	Q5CR08	Q5CQN0	Phosphoinositide phospholipase C.	Sac1p family protein.	0.908
cgd4_2560	cgd6_3390	Q5CR08	Q5CWX0	Phosphoinositide phospholipase C.	Phosphatidylinositol 4-kinase A; Belongs to the PI3/PI4-kinase family.	0.934
cgd4_2560	cgd6_3570	Q5CR08	Q5CWV5	Phosphoinositide phospholipase C.	Myotubularin related protein 1, C-terminus protein tyrosine/serine phosphatase, catalytic domain.	0.913
cgd4_2560	cgd7_1500	Q5CR08	Q5CYP7	Phosphoinositide phospholipase C.	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	0.570
cgd4_2560	cgd8_3280	Q5CR08	A3FPZ4	Phosphoinositide phospholipase C.	Phosphatidylinositol-4-phosphate 5-kinase, putative.	0.967
cgd4_2560	cgd8_4500	Q5CR08	Q5CVD3	Phosphoinositide phospholipase C.	Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.	0.939
cgd4_80	cgd2_1340	Q5CQN0	Q5CTW1	Sac1p family protein.	Possible phosphatidylinositol 3-and 4-kinase family protein.	0.564
cgd4_80	cgd2_1910	Q5CQN0	Q5CTR8	Sac1p family protein.	Putative phosphatidylinositol-4-phosphate 5-kinase, MORN beta hairpin repeats glycine-rich protein.	0.495