(6 nodes) Mitochondrial iron-sulfur cluster biogenesis network (Cryptosporidium parvum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd6_3000	Ferredoxin-like protein Fd1, putative. (167 aa)
	cgd5_4320	Frataxin like protein. (173 aa)
	cgd3_2810	DNAJ domain containing protein. (244 aa)
	cgd8_2710	Adrenodoxin-NADP+ reductase. (571 aa)
	cgd8_2530	With a signal peptide, low complexity region followed by a sushi domain. (1006 aa)
	cgd6_1050	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (150 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cgd3_2810	cgd5_4320	Q5CUH5	Q5CQ32	DNAJ domain containing protein.	Frataxin like protein.	0.907
cgd3_2810	cgd6_1050	Q5CUH5	Q5CXH7	DNAJ domain containing protein.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.996
cgd3_2810	cgd6_3000	Q5CUH5	A3FPV4	DNAJ domain containing protein.	Ferredoxin-like protein Fd1, putative.	0.845
cgd3_2810	cgd8_2530	Q5CUH5	Q5CVW6	DNAJ domain containing protein.	With a signal peptide, low complexity region followed by a sushi domain.	0.647
cgd5_4320	cgd3_2810	Q5CQ32	Q5CUH5	Frataxin like protein.	DNAJ domain containing protein.	0.907
cgd5_4320	cgd6_1050	Q5CQ32	Q5CXH7	Frataxin like protein.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.999
cgd5_4320	cgd6_3000	Q5CQ32	A3FPV4	Frataxin like protein.	Ferredoxin-like protein Fd1, putative.	0.918
cgd5_4320	cgd8_2530	Q5CQ32	Q5CVW6	Frataxin like protein.	With a signal peptide, low complexity region followed by a sushi domain.	0.999
cgd5_4320	cgd8_2710	Q5CQ32	Q5CVU8	Frataxin like protein.	Adrenodoxin-NADP+ reductase.	0.738
cgd6_1050	cgd3_2810	Q5CXH7	Q5CUH5	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	DNAJ domain containing protein.	0.996
cgd6_1050	cgd5_4320	Q5CXH7	Q5CQ32	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Frataxin like protein.	0.999
cgd6_1050	cgd6_3000	Q5CXH7	A3FPV4	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Ferredoxin-like protein Fd1, putative.	0.973
cgd6_1050	cgd8_2530	Q5CXH7	Q5CVW6	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	With a signal peptide, low complexity region followed by a sushi domain.	0.999
cgd6_1050	cgd8_2710	Q5CXH7	Q5CVU8	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Adrenodoxin-NADP+ reductase.	0.660
cgd6_3000	cgd3_2810	A3FPV4	Q5CUH5	Ferredoxin-like protein Fd1, putative.	DNAJ domain containing protein.	0.845
cgd6_3000	cgd5_4320	A3FPV4	Q5CQ32	Ferredoxin-like protein Fd1, putative.	Frataxin like protein.	0.918
cgd6_3000	cgd6_1050	A3FPV4	Q5CXH7	Ferredoxin-like protein Fd1, putative.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.973
cgd6_3000	cgd8_2530	A3FPV4	Q5CVW6	Ferredoxin-like protein Fd1, putative.	With a signal peptide, low complexity region followed by a sushi domain.	0.926
cgd6_3000	cgd8_2710	A3FPV4	Q5CVU8	Ferredoxin-like protein Fd1, putative.	Adrenodoxin-NADP+ reductase.	0.999
cgd8_2530	cgd3_2810	Q5CVW6	Q5CUH5	With a signal peptide, low complexity region followed by a sushi domain.	DNAJ domain containing protein.	0.647