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cgd1_2230 cgd1_2230 cgd4_690 cgd4_690 cgd1_190 cgd1_190 cgd3_3660 cgd3_3660 cgd8_3140 cgd8_3140 cgd6_4130 cgd6_4130 cgd6_3970 cgd6_3970 cgd7_5070 cgd7_5070
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cgd1_2230Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (398 aa)
cgd4_690Pyruvate:ferredoxin oxidoreductase/NADPH-cytochrome P450 reductase PNO. (1934 aa)
cgd1_190Narf-like protein nuclear prelamin A recognition factor; Belongs to the NARF family. (560 aa)
cgd3_3660Uncharacterized protein; Belongs to the BolA/IbaG family. (91 aa)
cgd8_3140Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (355 aa)
cgd6_4130Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (298 aa)
cgd6_3970Glutaredoxin-like protein 2 thioredoxin folds. (219 aa)
cgd7_5070Small conserved protein. (128 aa)
Your Current Organism:
Cryptosporidium parvum
NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II
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