(34 nodes) Negative regulation of gene expression network (Cryptosporidium parvum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	cgd8_1820	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (406 aa)
	cgd8_2980	KH_dom_type_1 domain-containing protein. (144 aa)
	cgd8_4460	Cell differentiation protein rcd1, putative. (390 aa)
	cgd3_780	KH_dom_type_1 domain-containing protein. (211 aa)
	cgd4_2710	Uncharacterized protein. (77 aa)
	cgd8_340	Exoribonuclease PH, putative. (295 aa)
	cgd3_280	mRNA translation inhibitor SKI2 SFII helicase, DEXDc+HELICc. (1439 aa)
	cgd4_4360	Ring finger domain containing protein. (657 aa)
	cgd4_3930	Archeo-eukaryotic exosomal RNAse. (351 aa)
	cgd5_3890	Possible apicomplexan specific, low complexity protein. (324 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (160 aa)
	cgd4_1950	RPR46-like RNAse PH domain. (244 aa)
	cgd4_1920	Endo/exonuclease/phosphatase domain-containing protein. (782 aa)
	cgd4_1850	RNase. (689 aa)
	cgd5_970	60S ribosomal protein L13A. (204 aa)
	cgd5_100	RRPp/PMC2 like exosome 3'-5' exoribonuclease subunit with an RNAseD domain and an HRDc domain. (957 aa)
	cgd2_3340	Ser/Thr protein kinase. (773 aa)
	cgd3_4320	RPOL4c domain-containing protein. (124 aa)
	cgd3_350	Pop2p-like 3'5' exonuclease, CCR4-NOT transcription complex. (277 aa)
	cgd8_4910	PAN2 family 3'5' exonuclease, UBC hydrolase (Inactive) plus nuclease. (1936 aa)
	cgd8_2250	Rat1 Kar1/Rat1 like 5'-3' exonuclease. (1350 aa)
	Pelota/Dom34	Pelota/Dom34 pelota like RNA binding domain. (461 aa)
	cgd6_3540	Archeo-eukaryotice exosomal RNAse PH. (303 aa)
	cgd6_2080	Kem1p-like 5'-3' exonuclease. (1588 aa)
	cgd6_2060	Cdc39p protein-like C-terminal Not1, CCR4-Not complex component Not1. (2664 aa)
	cgd6_1770	Protein with C2H2 Zn finger, ASR2B-like N-and C-terminus. (668 aa)
	cgd6_1700	Nuclear cap-binding protein subunit 2. (213 aa)
	cgd7_3520	Sm domain-containing protein. (73 aa)
	cgd7_2790	Regena domain protein (CCR-Not complex protein subunit 3), putative. (394 aa)
	cgd7_2710	Ataxin2 related nudix domain protein (RNA processing phosphatase/ATpase domain). (651 aa)
	cgd7_2380	RRP45-like archaeo-eukaryotic exosomal rnase, PH domain. (432 aa)
	cgd7_1600	Ribosomal protein of the PO/L10 family. (222 aa)
	cgd7_230	RPR45-like archaeo-eukaryotic exosomal RNAse PH. (291 aa)
	cgd7_60	Hat1-like acetyltransferase (Histone acetyltransferase-like). (423 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM1	cgd3_280	Q5CQ90	Q5CPF4	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	mRNA translation inhibitor SKI2 SFII helicase, DEXDc+HELICc.	0.604
LSM1	cgd3_350	Q5CQ90	Q5CV44	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Pop2p-like 3'5' exonuclease, CCR4-NOT transcription complex.	0.439
LSM1	cgd4_1850	Q5CQ90	Q5CR73	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	RNase.	0.455
LSM1	cgd4_1920	Q5CQ90	Q5CR66	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Endo/exonuclease/phosphatase domain-containing protein.	0.455
LSM1	cgd4_2710	Q5CQ90	A3FQL4	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Uncharacterized protein.	0.999
LSM1	cgd5_3890	Q5CQ90	Q5CQ73	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Possible apicomplexan specific, low complexity protein.	0.917
LSM1	cgd6_2060	Q5CQ90	Q5CX88	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Cdc39p protein-like C-terminal Not1, CCR4-Not complex component Not1.	0.655
LSM1	cgd6_2080	Q5CQ90	Q5CX86	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Kem1p-like 5'-3' exonuclease.	0.994
LSM1	cgd7_2710	Q5CQ90	Q5CYD9	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Ataxin2 related nudix domain protein (RNA processing phosphatase/ATpase domain).	0.959
LSM1	cgd7_3520	Q5CQ90	Q5CY65	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Sm domain-containing protein.	0.999
LSM1	cgd8_1820	Q5CQ90	A3FPY4	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.999
LSM1	cgd8_2250	Q5CQ90	Q5CVZ1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Rat1 Kar1/Rat1 like 5'-3' exonuclease.	0.527
LSM1	cgd8_4910	Q5CQ90	Q5CV96	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	PAN2 family 3'5' exonuclease, UBC hydrolase (Inactive) plus nuclease.	0.451
Pelota/Dom34	cgd3_280	Q5CW31	Q5CPF4	Pelota/Dom34 pelota like RNA binding domain.	mRNA translation inhibitor SKI2 SFII helicase, DEXDc+HELICc.	0.798
Pelota/Dom34	cgd5_970	Q5CW31	Q5CRY8	Pelota/Dom34 pelota like RNA binding domain.	60S ribosomal protein L13A.	0.809
Pelota/Dom34	cgd6_2080	Q5CW31	Q5CX86	Pelota/Dom34 pelota like RNA binding domain.	Kem1p-like 5'-3' exonuclease.	0.661
Pelota/Dom34	cgd7_1600	Q5CW31	Q5CYP0	Pelota/Dom34 pelota like RNA binding domain.	Ribosomal protein of the PO/L10 family.	0.648
cgd2_3340	cgd3_350	Q5CTE5	Q5CV44	Ser/Thr protein kinase.	Pop2p-like 3'5' exonuclease, CCR4-NOT transcription complex.	0.659
cgd2_3340	cgd4_1850	Q5CTE5	Q5CR73	Ser/Thr protein kinase.	RNase.	0.522
cgd2_3340	cgd4_1920	Q5CTE5	Q5CR66	Ser/Thr protein kinase.	Endo/exonuclease/phosphatase domain-containing protein.	0.522