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cgd5_230 cgd5_230 cgd5_680 cgd5_680 cgd5_930 cgd5_930 cgd5_2970 cgd5_2970 cgd5_2980 cgd5_2980 cgd4_1660 cgd4_1660 cgd4_2050 cgd4_2050 cgd4_2710 cgd4_2710 cgd4_3190 cgd4_3190 cgd4_3410 cgd4_3410 cgd4_1030 cgd4_1030 cgd4_4030 cgd4_4030 cgd3_140 cgd3_140 cgd6_230 cgd6_230 cgd2_360 cgd2_360 cgd2_270 cgd2_270 cgd4_4280 cgd4_4280 cgd8_650 cgd8_650 cgd8_630 cgd8_630 cgd5_4320 cgd5_4320 cgd5_4060 cgd5_4060 cgd5_3780 cgd5_3780 cgd4_1520 cgd4_1520 cgd4_1330 cgd4_1330 cgd4_1270 cgd4_1270 cgd4_760 cgd4_760 cgd4_720 cgd4_720 cgd4_690 cgd4_690 cgd4_660 cgd4_660 cgd4_650 cgd4_650 cgd4_150 cgd4_150 cgd4_130 cgd4_130 cgd4_90 cgd4_90 cgd4_70 cgd4_70 cgd4_3770 cgd4_3770 EIF6 EIF6 cgd4_2260 cgd4_2260 cgd4_2010 cgd4_2010 cgd5_3540 cgd5_3540 cgd5_3170 cgd5_3170 cgd5_2960 cgd5_2960 cgd5_2360 cgd5_2360 cgd5_2350 cgd5_2350 cgd5_1810 cgd5_1810 cgd5_1790 cgd5_1790 cgd5_1690 cgd5_1690 cgd5_1680 cgd5_1680 cgd5_920 cgd5_920 cgd5_900 cgd5_900 Reptin52 Reptin52 cgd5_390 cgd5_390 cgd1_3620 cgd1_3620 cgd1_3480 cgd1_3480 cgd1_3020 cgd1_3020 cgd1_2960 cgd1_2960 cgd1_2730 cgd1_2730 cgd1_2580 cgd1_2580 cgd1_1840 cgd1_1840 cgd1_1410 cgd1_1410 cgd1_850 cgd1_850 cgd1_270 cgd1_270 cgd1_190 cgd1_190 cgd2_3220 cgd2_3220 cgd2_1500 cgd2_1500 cgd2_1160 cgd2_1160 cgd2_1000 cgd2_1000 cgd2_770 cgd2_770 cgd3_4320 cgd3_4320 cgd3_4020 cgd3_4020 cgd3_3970 cgd3_3970 cgd3_2960 cgd3_2960 cgd3_2890 cgd3_2890 cgd3_2810 cgd3_2810 cgd3_2090 cgd3_2090 cgd3_1880 cgd3_1880 cgd1_2690 cgd1_2690 cgd1_2230 cgd1_2230 cgd1_200 cgd1_200 cgd2_4070 cgd2_4070 cgd8_1820 cgd8_1820 cgd6_4210 cgd6_4210 cgd6_3960 cgd6_3960 cgd6_2140 cgd6_2140 cgd6_1900 cgd6_1900 cgd7_3970 cgd7_3970 cgd7_2090 cgd7_2090 cgd7_560 cgd7_560 cgd7_20 cgd7_20 cgd7_60 cgd7_60 LSM3 LSM3 cgd3_1200 cgd3_1200 cgd3_1030 cgd3_1030 cgd8_5230 cgd8_5230 cgd8_4680 cgd8_4680 cgd8_4430 cgd8_4430 cgd8_3970 cgd8_3970 cgd8_3310 cgd8_3310 cgd8_3140 cgd8_3140 cgd8_2830 cgd8_2830 cgd8_2380 cgd8_2380 cgd8_2040 cgd8_2040 cgd8_1690 cgd8_1690 cgd8_1060 cgd8_1060 cgd8_880 cgd8_880 cgd6_4750 cgd6_4750 cgd6_4320 cgd6_4320 cgd6_4310 cgd6_4310 cgd6_4190 cgd6_4190 cgd6_4130 cgd6_4130 cgd6_3810 cgd6_3810 cgd6_3180 cgd6_3180 cgd6_2830 cgd6_2830 cgd6_2550 cgd6_2550 cgd6_1870 cgd6_1870 cgd6_1780 cgd6_1780 cgd6_1760 cgd6_1760 P23 P23 cgd6_1560 cgd6_1560 cgd6_1050 cgd6_1050 cgd6_680 cgd6_680 cgd7_5490 cgd7_5490 cgd7_5180 cgd7_5180 cgd7_5070 cgd7_5070 cgd7_4460 cgd7_4460 cgd7_3690 cgd7_3690 cgd7_3100 cgd7_3100 cgd7_3060 cgd7_3060 cgd7_3040 cgd7_3040 cgd7_2430 cgd7_2430 cgd7_2370 cgd7_2370 cgd7_970 cgd7_970 cgd7_1080 cgd7_1080 cgd7_1600 cgd7_1600 cgd7_1690 cgd7_1690 cgd7_1700 cgd7_1700 cgd7_1980 cgd7_1980
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cgd5_230Uncharacterized protein. (464 aa)
cgd5_680Eukaryotic translation initiation factor 3 37.28 kDa subunit, putative. (261 aa)
cgd5_930Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (180 aa)
cgd5_2970Uncharacterized protein. (622 aa)
cgd5_2980SEC63 domain-containing protein. (367 aa)
cgd4_1660Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
cgd4_2050RECA_2 domain-containing protein. (133 aa)
cgd4_2710Uncharacterized protein. (77 aa)
cgd4_3190Small nuclear ribonucleoprotein Sm D2. (106 aa)
cgd4_3410RNA binding protein, putative. (906 aa)
cgd4_1030Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (352 aa)
cgd4_4030Uncharacterized protein. (202 aa)
cgd3_140B-tubulin specific chaparone. (1470 aa)
cgd6_230APG6 domain-containing protein. (443 aa)
cgd2_360Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (724 aa)
cgd2_270Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (545 aa)
cgd4_4280Spindle pole body component. (311 aa)
cgd8_65060S ribosomal protein L23A; Belongs to the universal ribosomal protein uL23 family. (156 aa)
cgd8_63026S proteasome regulatory complex, subunit PSMD5. (505 aa)
cgd5_4320Frataxin like protein. (173 aa)
cgd5_4060Matrin-type domain-containing protein. (198 aa)
cgd5_3780HIT-type domain-containing protein. (283 aa)
cgd4_1520Brx1p nucleolar protein required for biogenesis of the 60S ribosomal subunit. (353 aa)
cgd4_1330NADPH-dependent FMN FAD containing oxidoreductase. (819 aa)
cgd4_1270Transcription factor TFIIIB, SANT domain. (278 aa)
cgd4_760Putative ASF1 anti-silencing function 1 like protein. (246 aa)
cgd4_720Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (347 aa)
cgd4_690Pyruvate:ferredoxin oxidoreductase/NADPH-cytochrome P450 reductase PNO. (1934 aa)
cgd4_660Nip7 like PUA domain containing protein involved in ribosomal biogenesis. (183 aa)
cgd4_650Transcription initiation factor IID. (1965 aa)
cgd4_150Pre-mRNA splicing protein Prp31p--like. (463 aa)
cgd4_130RRM domain and KH domain protein (SPAC30D11.14-like KH). (801 aa)
cgd4_90RRP7 domain-containing protein. (176 aa)
cgd4_70Uncharacterized protein. (718 aa)
cgd4_3770Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1040 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (252 aa)
cgd4_226060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa)
cgd4_2010CDC73_C domain-containing protein. (476 aa)
cgd5_3540Cyclin domain protein. (648 aa)
cgd5_3170Histone H2B; Belongs to the histone H2B family. (152 aa)
cgd5_2960U5snrp Brr2 SFII RNA helicase (sec63 and the second part of the RNA). (1204 aa)
cgd5_2360P27 like 26S proteasomal subunit with a PDZ domain. (249 aa)
cgd5_2350SnRNP assembly defective 1 like ubiquitin C-terminal hydrolase with a UBP finger at the N-terminus. (498 aa)
cgd5_1810SMART 2xt_SNARE domain containing protein. (204 aa)
cgd5_1790Conserved eukaryotic protein. (175 aa)
cgd5_1690Cactin-like protein. (548 aa)
cgd5_1680Protein with an N-terminal domain shared with the TOG/ALp4p ike microtubule associated proteins. (1359 aa)
cgd5_920Pre-mRNA splicing factor Pro1/Prp6. HAT repeat protein. (923 aa)
cgd5_900MRP like MinD family ATpase. (611 aa)
Reptin52RuvB-like helicase; Belongs to the RuvB family. (479 aa)
cgd5_390Putative eukaryotic translation initiation factor 3. (1030 aa)
cgd1_3620Transcription factor TAF7p/TAFII55. (368 aa)
cgd1_3480Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (456 aa)
cgd1_3020Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (369 aa)
cgd1_2960Protein kinase CMGC group, Sky1p like S/T protein kinase probably involved in RNA metabolism. (765 aa)
cgd1_2730Ro ribonucleoprotein-binding protein 1, RNA binding protein with 3x RRM domains. (693 aa)
cgd1_2580Arl1p/ARF like GTpase involved in vesicular transport. (247 aa)
cgd1_1840Uncharacterized protein. (932 aa)
cgd1_1410Uncharacterized protein. (247 aa)
cgd1_85040S ribosomal protein S19. (154 aa)
cgd1_270Zinc finger protein. (145 aa)
cgd1_190Narf-like protein nuclear prelamin A recognition factor; Belongs to the NARF family. (560 aa)
cgd2_3220Sc6p-like, SM domain. (377 aa)
cgd2_1500Possible translation initiation factor with possible PINT domain; Belongs to the eIF-3 subunit E family. (540 aa)
cgd2_1160Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (673 aa)
cgd2_1000Bruno-like, RRM domain RNA binding protein. (639 aa)
cgd2_770Bac_surface_Ag domain-containing protein. (450 aa)
cgd3_4320RPOL4c domain-containing protein. (124 aa)
cgd3_4020eIF-3 p25/subunit 11. (262 aa)
cgd3_3970Yer007c-ap/MCT-1 like PUA RNA binding domain containing protein. (179 aa)
cgd3_2960Uncharacterized protein. (2691 aa)
cgd3_2890Prp8. JAB/PAD domain. (2379 aa)
cgd3_2810DNAJ domain containing protein. (244 aa)
cgd3_209040S ribosomal protein SAe. (260 aa)
cgd3_1880Protein with 2x rrm domains. (1142 aa)
cgd1_2690Sm domain-containing protein. (67 aa)
cgd1_2230Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (398 aa)
cgd1_200ADP-ribosylation factor-like protein 2 (ARL2), putative; Belongs to the small GTPase superfamily. Arf family. (183 aa)
cgd2_4070RECA_2 domain-containing protein. (304 aa)
cgd8_1820ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (406 aa)
cgd6_4210Kinesin-like boursin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
cgd6_3960Elongation factor-like protein. (1100 aa)
cgd6_2140Conserved hypothetical multi-pass transmembrane protein, possible ion transporter. (1017 aa)
cgd6_1900Kinesin heavy chain, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (714 aa)
cgd7_3970Small nuclear ribonucleoprotein, putative. (62 aa)
cgd7_2090RuvB-like helicase; Belongs to the RuvB family. (457 aa)
cgd7_560WD_REPEATS_REGION domain-containing protein. (664 aa)
cgd7_20ANK_REP_REGION domain-containing protein. (216 aa)
cgd7_60Hat1-like acetyltransferase (Histone acetyltransferase-like). (423 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
cgd3_1200Possible prefoldin-related protein. (127 aa)
cgd3_1030Uncharacterized low complexity protein. (465 aa)
cgd8_5230Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
cgd8_4680Conserved protein Py hit 23481194. (332 aa)
cgd8_4430Translation initiation factor if-2 betam beta subunit ZnR. (214 aa)
cgd8_3970NAP, nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (197 aa)
cgd8_3310Ylr022cp-like protein that has a C2H2 zinc finger and is a component of the exosome. (379 aa)
cgd8_3140Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (355 aa)
cgd8_2830LRR repeats protein. (511 aa)
cgd8_2380CDC45 like protein, possible horizontal transfer. (706 aa)
cgd8_2040POZ domain protein, related to tetramerization domain of K channel. (242 aa)
cgd8_1690Uncharacterized protein. (109 aa)
cgd8_1060Uncharacterized conserved protein. (701 aa)
cgd8_880Transcription initiation factor TFIIB Sua7p ZnR+2cyclins. (456 aa)
cgd6_4750Splicing factor 3B subunit1-like HEAT repeat containing protein. (1031 aa)
cgd6_432040S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (207 aa)
cgd6_4310Putative low complexity. (1931 aa)
cgd6_419060S ribosomal protein L10, alpha/beta hammerhead. (222 aa)
cgd6_4130Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (298 aa)
cgd6_3810Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (277 aa)
cgd6_318040S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (152 aa)
cgd6_2830Splicing factor 3a 66kD N-terminus C2H2 domain. (216 aa)
cgd6_2550Uncharacterized protein. (380 aa)
cgd6_1870Signal recognition particle SPR19. (174 aa)
cgd6_1780Dhh1-like SF II RNA helicase; Belongs to the DEAD box helicase family. (581 aa)
cgd6_1760Phosphatidylinositol 3-kinase PI3ka plus PI3Kc domains; Belongs to the PI3/PI4-kinase family. (943 aa)
P23P23 HSP20-like chaperones fold. (213 aa)
cgd6_1560Yju2p / cwf16-like Zn finger. (270 aa)
cgd6_1050Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (150 aa)
cgd6_680Conserved protein with possible C2 domain. (1665 aa)
cgd7_5490PRP18 (SFM+PRP18 domains). (337 aa)
cgd7_5180Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (450 aa)
cgd7_5070Small conserved protein. (128 aa)
cgd7_446060S ribosomal protein L6. (184 aa)
cgd7_3690Crooked neck protein HAT repeats. (736 aa)
cgd7_3100LsmAD domain-containing protein. (554 aa)
cgd7_3060Spindle pole body component. (983 aa)
cgd7_3040Membrane protein conserved in eukaryotes. (1654 aa)
cgd7_2430Translation initiation factor eIF-5 Tif5p, ZnR+W2 domains. (460 aa)
cgd7_2370EB1 like microtubule binding protein. (285 aa)
cgd7_970Syf1p. protein with 8 HAT domains. (1020 aa)
cgd7_1080eIF3-p47 with JAB/PAD domain. (349 aa)
cgd7_1600Ribosomal protein of the PO/L10 family. (222 aa)
cgd7_1690Meiotic recombination protein DMC1-like protein; Belongs to the RecA family. (342 aa)
cgd7_1700Histone H2B; Belongs to the histone H2B family. (131 aa)
cgd7_1980Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (492 aa)
Your Current Organism:
Cryptosporidium parvum
NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II
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