(25 nodes) Meiotic cell cycle network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd3_2720	Putative topoisomerase VIA. (235 aa)
	cgd1_1420	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1). (513 aa)
	cgd5_230	Uncharacterized protein. (464 aa)
	cgd4_2050	RECA_2 domain-containing protein. (133 aa)
	cgd4_4280	Spindle pole body component. (311 aa)
	cgd4_2970	RAD1, NH2 terminal ERCC4-like helicase domain. (631 aa)
	cgd4_2960	ERCC4/XP-G-type excision repair nuclease. (308 aa)
	cgd4_1710	Low complexity protein. (1466 aa)
	cgd5_1750	Conserved protein with N-terminal HORMA domain. (403 aa)
	cgd1_3420	Conserved possible MUS81 endonuclease. (734 aa)
	cgd1_2410	RAD50. (1062 aa)
	cgd1_840	Mnd1 domain-containing protein. (66 aa)
	cgd2_510	Hypothetical coiled coil protein. (302 aa)
	cgd3_950	Hypothetical conserved protein. (706 aa)
	cgd8_5190	Large protein with central conserved domain, possible BCRT domain. (1442 aa)
	cgd8_4070	SANT domain containing protein. (1632 aa)
	cgd8_1350	Topoisomerase VIA/SpoII nuclease subunit, toprim domain. (360 aa)
	cgd6_4300	Putative coiled coil protein. (724 aa)
	Hus1-like	Hus1-like mitotic and DNA damage checkpoint protein. (336 aa)
	cgd6_730	14-3-3 domain containing protein. (1937 aa)
	cgd6_550	Pch2p like AAA ATpase; Belongs to the AAA ATPase family. (546 aa)
	cgd7_3060	Spindle pole body component. (983 aa)
	cgd7_2760	Separin (Caspase fold protease). (2442 aa)
	cgd7_2000	Bub1p related protein kinase. (850 aa)
	cgd7_1690	Meiotic recombination protein DMC1-like protein; Belongs to the RecA family. (342 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hus1-like	cgd1_1420	Q5CXE6	A3FQD2	Hus1-like mitotic and DNA damage checkpoint protein.	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	0.844
Hus1-like	cgd1_2410	Q5CXE6	Q5CSJ7	Hus1-like mitotic and DNA damage checkpoint protein.	RAD50.	0.569
Hus1-like	cgd1_3420	Q5CXE6	Q5CSB1	Hus1-like mitotic and DNA damage checkpoint protein.	Conserved possible MUS81 endonuclease.	0.648
Hus1-like	cgd3_2720	Q5CXE6	A3FQ36	Hus1-like mitotic and DNA damage checkpoint protein.	Putative topoisomerase VIA.	0.400
Hus1-like	cgd4_2050	Q5CXE6	A3FQK6	Hus1-like mitotic and DNA damage checkpoint protein.	RECA_2 domain-containing protein.	0.522
Hus1-like	cgd4_2960	Q5CXE6	Q5CQX1	Hus1-like mitotic and DNA damage checkpoint protein.	ERCC4/XP-G-type excision repair nuclease.	0.547
Hus1-like	cgd4_2970	Q5CXE6	Q5CQX0	Hus1-like mitotic and DNA damage checkpoint protein.	RAD1, NH2 terminal ERCC4-like helicase domain.	0.547
Hus1-like	cgd5_1750	Q5CXE6	Q5CRR7	Hus1-like mitotic and DNA damage checkpoint protein.	Conserved protein with N-terminal HORMA domain.	0.549
Hus1-like	cgd7_1690	Q5CXE6	Q5CYN2	Hus1-like mitotic and DNA damage checkpoint protein.	Meiotic recombination protein DMC1-like protein; Belongs to the RecA family.	0.522
Hus1-like	cgd7_2000	Q5CXE6	Q5CYK3	Hus1-like mitotic and DNA damage checkpoint protein.	Bub1p related protein kinase.	0.744
Hus1-like	cgd7_2760	Q5CXE6	Q5CYD5	Hus1-like mitotic and DNA damage checkpoint protein.	Separin (Caspase fold protease).	0.750
Hus1-like	cgd8_1350	Q5CXE6	Q5CW77	Hus1-like mitotic and DNA damage checkpoint protein.	Topoisomerase VIA/SpoII nuclease subunit, toprim domain.	0.400
Hus1-like	cgd8_4070	Q5CXE6	Q5CVH1	Hus1-like mitotic and DNA damage checkpoint protein.	SANT domain containing protein.	0.664
Hus1-like	cgd8_5190	Q5CXE6	Q5CV72	Hus1-like mitotic and DNA damage checkpoint protein.	Large protein with central conserved domain, possible BCRT domain.	0.513
cgd1_1420	Hus1-like	A3FQD2	Q5CXE6	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	Hus1-like mitotic and DNA damage checkpoint protein.	0.844
cgd1_1420	cgd1_2410	A3FQD2	Q5CSJ7	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	RAD50.	0.999
cgd1_1420	cgd1_3420	A3FQD2	Q5CSB1	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	Conserved possible MUS81 endonuclease.	0.810
cgd1_1420	cgd1_840	A3FQD2	Q5CSY4	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	Mnd1 domain-containing protein.	0.632
cgd1_1420	cgd3_2720	A3FQD2	A3FQ36	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	Putative topoisomerase VIA.	0.663
cgd1_1420	cgd4_2050	A3FQD2	A3FQK6	DNA repair and meiosis protein Mre11 (Emb/CAB50793.1).	RECA_2 domain-containing protein.	0.775