(16 nodes) Precatalytic spliceosome network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd7_3970	Small nuclear ribonucleoprotein, putative. (62 aa)
	cgd6_2400	Uncharacterized protein. (100 aa)
	cgd3_2310	RRM domain-containing protein. (86 aa)
	cgd4_1660	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	cgd4_3190	Small nuclear ribonucleoprotein Sm D2. (106 aa)
	cgd4_890	Uncharacterized protein. (85 aa)
	cgd4_150	Pre-mRNA splicing protein Prp31p--like. (463 aa)
	cgd1_2250	Small nuclear ribonucleoprotein Sm D3. (143 aa)
	cgd2_3510	Cus1p U2 snRNP protein. (602 aa)
	cgd3_3070	WD-40 repeat protein, SMART LisH domain. (595 aa)
	cgd3_1920	Possible PRP38 pre-mRNA splicing factor family member. (261 aa)
	cgd3_1440	U1 small nuclear ribonucleoprotein c like finger. (225 aa)
	cgd6_3490	RNA-binding protein, putative. (153 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
	cgd7_1070	SnRNP core protein. (107 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	LSM8	Q5CYX1	Q5CXQ2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	cgd1_2250	Q5CYX1	Q5CSL0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.994
LSM3	cgd2_3510	Q5CYX1	Q5CTD1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Cus1p U2 snRNP protein.	0.938
LSM3	cgd3_1440	Q5CYX1	Q5CUU5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U1 small nuclear ribonucleoprotein c like finger.	0.529
LSM3	cgd3_1920	Q5CYX1	Q5CUQ1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Possible PRP38 pre-mRNA splicing factor family member.	0.539
LSM3	cgd3_2310	Q5CYX1	A3FQ28	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	RRM domain-containing protein.	0.726
LSM3	cgd3_3070	Q5CYX1	Q5CUF2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	WD-40 repeat protein, SMART LisH domain.	0.437
LSM3	cgd4_150	Q5CYX1	Q5CQM4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA splicing protein Prp31p--like.	0.996
LSM3	cgd4_1660	Q5CYX1	A3FQK4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.997
LSM3	cgd4_3190	Q5CYX1	A3FQL7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D2.	0.997
LSM3	cgd4_890	Q5CYX1	A3FQN7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.918
LSM3	cgd6_2400	Q5CYX1	A3FPU6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.938
LSM3	cgd6_3490	Q5CYX1	Q5CWW2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	RNA-binding protein, putative.	0.686
LSM3	cgd7_1070	Q5CYX1	Q5CYT7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	SnRNP core protein.	0.999
LSM3	cgd7_3970	Q5CYX1	A3FPQ3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein, putative.	0.985
LSM8	LSM3	Q5CXQ2	Q5CYX1	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM8	cgd1_2250	Q5CXQ2	Q5CSL0	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.996
LSM8	cgd2_3510	Q5CXQ2	Q5CTD1	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Cus1p U2 snRNP protein.	0.872
LSM8	cgd3_1440	Q5CXQ2	Q5CUU5	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	U1 small nuclear ribonucleoprotein c like finger.	0.616
LSM8	cgd3_1920	Q5CXQ2	Q5CUQ1	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Possible PRP38 pre-mRNA splicing factor family member.	0.635