(27 nodes) Catalytic step 2 spliceosome network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd5_1790	Conserved eukaryotic protein. (175 aa)
	cgd7_520	Cyclin'cyclophilin like peptidyl-prolyl cis-trans isomerase fused to WD40 repeats at the N-terminus. (778 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	cgd7_970	Syf1p. protein with 8 HAT domains. (1020 aa)
	cgd7_1070	SnRNP core protein. (107 aa)
	cgd7_2160	Pre-mRNA splicing factor SF3a. 2xSWAP domain protein. (462 aa)
	cgd7_3520	Sm domain-containing protein. (73 aa)
	cgd7_3690	Crooked neck protein HAT repeats. (736 aa)
	cgd7_5320	Cwf5-like with 2 ZnR domains (CCCH and RRM domains missing). (186 aa)
	cgd6_2830	Splicing factor 3a 66kD N-terminus C2H2 domain. (216 aa)
	cgd6_4750	Splicing factor 3B subunit1-like HEAT repeat containing protein. (1031 aa)
	cgd8_1950	Protein CWC15. (214 aa)
	cgd8_2960	NIC+MI domains containing protein. nucampholin/yeast Cwc22p like protein involved in mRNA splicing. (619 aa)
	cgd3_2890	Prp8. JAB/PAD domain. (2379 aa)
	cgd3_3880	Snu114p GTpase, U5 snRNP-specific protein, 116 kDa. (1035 aa)
	cgd2_2810	Uncharacterized protein. (230 aa)
	cgd2_3510	Cus1p U2 snRNP protein. (602 aa)
	cgd1_2250	Small nuclear ribonucleoprotein Sm D3. (143 aa)
	cgd7_3960	Pleiotropic regulator 1. (427 aa)
	cgd7_3970	Small nuclear ribonucleoprotein, putative. (62 aa)
	cgd3_2310	RRM domain-containing protein. (86 aa)
	cgd2_1660	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (169 aa)
	cgd1_1800	Transducin / WD-40 repeat protein family. (493 aa)
	cgd1_2690	Sm domain-containing protein. (67 aa)
	cgd4_3190	Small nuclear ribonucleoprotein Sm D2. (106 aa)
	cgd4_3140	WD repeat protein. (343 aa)
	cgd5_920	Pre-mRNA splicing factor Pro1/Prp6. HAT repeat protein. (923 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	cgd1_2250	Q5CYX1	Q5CSL0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.994
LSM3	cgd1_2690	Q5CYX1	A3FQF0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.988
LSM3	cgd2_1660	Q5CYX1	A3FQ68	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.453
LSM3	cgd2_3510	Q5CYX1	Q5CTD1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Cus1p U2 snRNP protein.	0.938
LSM3	cgd3_2310	Q5CYX1	A3FQ28	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	RRM domain-containing protein.	0.726
LSM3	cgd3_2890	Q5CYX1	Q5CUG7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Prp8. JAB/PAD domain.	0.994
LSM3	cgd3_3880	Q5CYX1	Q5CU80	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Snu114p GTpase, U5 snRNP-specific protein, 116 kDa.	0.994
LSM3	cgd4_3140	Q5CYX1	Q5CQV4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	WD repeat protein.	0.597
LSM3	cgd4_3190	Q5CYX1	A3FQL7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D2.	0.997
LSM3	cgd5_920	Q5CYX1	Q5CRZ2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA splicing factor Pro1/Prp6. HAT repeat protein.	0.978
LSM3	cgd6_2830	Q5CYX1	Q5CX23	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3a 66kD N-terminus C2H2 domain.	0.904
LSM3	cgd6_4750	Q5CYX1	Q5CWK2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3B subunit1-like HEAT repeat containing protein.	0.897
LSM3	cgd7_1070	Q5CYX1	Q5CYT7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	SnRNP core protein.	0.999
LSM3	cgd7_2160	Q5CYX1	Q5CYJ0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA splicing factor SF3a. 2xSWAP domain protein.	0.932
LSM3	cgd7_3520	Q5CYX1	Q5CY65	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.999
LSM3	cgd7_3690	Q5CYX1	Q5CY48	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Crooked neck protein HAT repeats.	0.974
LSM3	cgd7_3970	Q5CYX1	A3FPQ3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein, putative.	0.985
LSM3	cgd7_970	Q5CYX1	Q5CYU5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Syf1p. protein with 8 HAT domains.	0.451
LSM3	cgd8_1950	Q5CYX1	Q5CW20	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Protein CWC15.	0.666
cgd1_1800	cgd1_2250	A3FQD4	Q5CSL0	Transducin / WD-40 repeat protein family.	Small nuclear ribonucleoprotein Sm D3.	0.987