37 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4CL55_TRYCC	Trypanothione reductase, putative. (189 aa)
	Q4CM56_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CMH3_TRYCC	Protein disulfide isomerase, putative. (163 aa)
	Q4CMQ7_TRYCC	Trypanothione reductase, putative. (388 aa)
	Q4CNS3_TRYCC	Thioredoxin, putative. (393 aa)
	Q4CPZ0_TRYCC	Calreticulin. (401 aa)
	Q4CSX7_TRYCC	Peptide methionine sulfoxide reductase, putative. (177 aa)
	Q4CT43_TRYCC	Trypanothione reductase, putative. (492 aa)
	Q4CVR5_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CX87_TRYCC	Tryparedoxin peroxidase, putative. (226 aa)
	Q4CY92_TRYCC	Tryparedoxin peroxidase, putative. (113 aa)
	Q4D004_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (263 aa)
	Q4D1B8_TRYCC	Tryparedoxin, putative. (144 aa)
	Q4D1B9_TRYCC	Tryparedoxin, putative. (193 aa)
	Q4D2Z9_TRYCC	Tryparedoxin peroxidase. (199 aa)
	Q4D301_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4D9I5_TRYCC	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (233 aa)
	Q4DDX3_TRYCC	Calreticulin. (401 aa)
	Q4DE24_TRYCC	Uncharacterized protein. (2533 aa)
	Q4DEJ4_TRYCC	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (178 aa)
	Q4DEJ6_TRYCC	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (164 aa)
	Q4DFA5_TRYCC	Thioredoxin domain-containing protein. (163 aa)
	Q4DFA6_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (376 aa)
	Q4DGB1_TRYCC	Glutaredoxin, putative. (107 aa)
	Q4DJ25_TRYCC	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	Q4DJ86_TRYCC	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (178 aa)
	Q4DK88_TRYCC	Peptide methionine sulfoxide reductase, putative. (177 aa)
	Q4DM29_TRYCC	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	Q4DQI9_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (181 aa)
	Q4DTP1_TRYCC	MsrB domain-containing protein. (182 aa)
	Q4DUE9_TRYCC	Endoplasmic reticulum oxidoreductin, putative. (443 aa)
	Q4DV70_TRYCC	Thioredoxin domain-containing protein. (153 aa)
	Q4DV71_TRYCC	Protein disulfide isomerase, putative. (141 aa)
	Q4E156_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (209 aa)
	Q4E3F7_TRYCC	Protein disulfide-isomerase. (481 aa)
	Q4E5B1_TRYCC	Thioredoxin, putative. (441 aa)
	TRS	Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family. (647 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CL55_TRYCC	Q4CM56_TRYCC	Q4CL55	Q4CM56	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CMH3_TRYCC	Q4CL55	Q4CMH3	Trypanothione reductase, putative.	Protein disulfide isomerase, putative.	0.463
Q4CL55_TRYCC	Q4CNS3_TRYCC	Q4CL55	Q4CNS3	Trypanothione reductase, putative.	Thioredoxin, putative.	0.465
Q4CL55_TRYCC	Q4CVR5_TRYCC	Q4CL55	Q4CVR5	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CX87_TRYCC	Q4CL55	Q4CX87	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CY92_TRYCC	Q4CL55	Q4CY92	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4D004_TRYCC	Q4CL55	Q4D004	Trypanothione reductase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.465
Q4CL55_TRYCC	Q4D1B8_TRYCC	Q4CL55	Q4D1B8	Trypanothione reductase, putative.	Tryparedoxin, putative.	0.805
Q4CL55_TRYCC	Q4D1B9_TRYCC	Q4CL55	Q4D1B9	Trypanothione reductase, putative.	Tryparedoxin, putative.	0.805
Q4CL55_TRYCC	Q4D2Z9_TRYCC	Q4CL55	Q4D2Z9	Trypanothione reductase, putative.	Tryparedoxin peroxidase.	0.885
Q4CL55_TRYCC	Q4D301_TRYCC	Q4CL55	Q4D301	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4DE24_TRYCC	Q4CL55	Q4DE24	Trypanothione reductase, putative.	Uncharacterized protein.	0.567
Q4CL55_TRYCC	Q4DEJ4_TRYCC	Q4CL55	Q4DEJ4	Trypanothione reductase, putative.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.822
Q4CL55_TRYCC	Q4DEJ6_TRYCC	Q4CL55	Q4DEJ6	Trypanothione reductase, putative.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.822
Q4CL55_TRYCC	Q4DFA5_TRYCC	Q4CL55	Q4DFA5	Trypanothione reductase, putative.	Thioredoxin domain-containing protein.	0.463
Q4CL55_TRYCC	Q4DFA6_TRYCC	Q4CL55	Q4DFA6	Trypanothione reductase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.465
Q4CL55_TRYCC	Q4DGB1_TRYCC	Q4CL55	Q4DGB1	Trypanothione reductase, putative.	Glutaredoxin, putative.	0.810
Q4CL55_TRYCC	Q4DJ25_TRYCC	Q4CL55	Q4DJ25	Trypanothione reductase, putative.	Thioredoxin; Belongs to the thioredoxin family.	0.567
Q4CL55_TRYCC	Q4DJ86_TRYCC	Q4CL55	Q4DJ86	Trypanothione reductase, putative.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.822
Q4CL55_TRYCC	Q4DM29_TRYCC	Q4CL55	Q4DM29	Trypanothione reductase, putative.	Thioredoxin; Belongs to the thioredoxin family.	0.567