55 items (Trypanosoma cruzi) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	Q4CL61_TRYCC	3,2-trans-enoyl-coA isomerase, mitochondrial, putative. (100 aa)
	Q4CLW3_TRYCC	Trifunctional enzyme alpha subunit, mitochondrial-like protein, putative. (687 aa)
	Q4CML2_TRYCC	Glucose-6-phosphate dehydrogenase, putative. (279 aa)
	Q4CMP6_TRYCC	NAD(P)-dependent steroid dehydrogenase protein, putative. (224 aa)
	Q4CR34_TRYCC	Uncharacterized protein. (310 aa)
	Q4CRI1_TRYCC	3,2-trans-enoyl-CoA isomerase, mitochondrial, putative; Belongs to the enoyl-CoA hydratase/isomerase family. (352 aa)
	Q4CSB2_TRYCC	NADP-dependent alcohol hydrogenase, putative. (347 aa)
	Q4CTQ3_TRYCC	3,2-trans-enoyl-CoA isomerase, mitochondrial, putative. (398 aa)
	Q4CTR7_TRYCC	Malate dehydrogenase. (332 aa)
	Q4CU39_TRYCC	L-threonine 3-dehydrogenase, putative. (332 aa)
	Q4CU50_TRYCC	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative. (346 aa)
	Q4CU51_TRYCC	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative. (198 aa)
	Q4CU52_TRYCC	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative. (253 aa)
	Q4CWB6_TRYCC	Trifunctional enzyme alpha subunit, mitochondrial-like protein. (691 aa)
	Q4CWM8_TRYCC	Short chain dehydrogenase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
	Q4CXJ3_TRYCC	3,2-trans-enoyl-CoA isomerase, mitochondrial, putative; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
	Q4CZI4_TRYCC	Glucose-6-phosphate 1-dehydrogenase, putative. (272 aa)
	Q4D0X5_TRYCC	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (477 aa)
	Q4D123_TRYCC	Malate dehydrogenase. (332 aa)
	Q4D249_TRYCC	Epimerase domain-containing protein. (415 aa)
	Q4D2W4_TRYCC	6-phosphogluconate dehydrogenase, decarboxylating, putative. (280 aa)
	Q4D4A0_TRYCC	Malate dehydrogenase. (301 aa)
	Q4D4A1_TRYCC	Malate dehydrogenase. (374 aa)
	Q4D4C9_TRYCC	3-hydroxy-3-methylglutaryl coenzyme A reductase. (435 aa)
	Q4D8T0_TRYCC	Trifunctional enzyme alpha subunit, mitochondrial-like protein. (95 aa)
	Q4D8W2_TRYCC	Enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase, putative. (793 aa)
	Q4DAE1_TRYCC	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative. (340 aa)
	Q4DB76_TRYCC	Enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase, putative. (792 aa)
	Q4DBK7_TRYCC	Uncharacterized protein. (328 aa)
	Q4DDK8_TRYCC	Glycosomal malate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (323 aa)
	Q4DEF3_TRYCC	NADP-dependent alcohol hydrogenase, putative. (351 aa)
	GMPR	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (491 aa)
	Q4DFP0_TRYCC	NADP-dependent alcohol hydrogenase, putative. (351 aa)
	Q4DG65_TRYCC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa)
	Q4DGE7_TRYCC	UDP-glucose 6-dehydrogenase. (501 aa)
	Q4DGX8_TRYCC	Uncharacterized protein. (327 aa)
	Q4DID7_TRYCC	Short-chain dehydrogenase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
	PGFS_TRYCC	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde. (283 aa)
	Q4DJ68_TRYCC	Malic enzyme. (565 aa)
	Q4DJ69_TRYCC	Malic enzyme. (573 aa)
	Q4DQR5_TRYCC	3-hydroxy-3-methylglutaryl coenzyme A reductase. (452 aa)
	Q4DRD8_TRYCC	Glycosomal malate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (323 aa)
	Q4DSB7_TRYCC	Uncharacterized protein. (310 aa)
	Q4DU92_TRYCC	6-phosphogluconate dehydrogenase, decarboxylating. (145 aa)
	Q4DV36_TRYCC	Malic enzyme. (565 aa)
	Q4DV37_TRYCC	Malic enzyme. (573 aa)
	Q4DW93_TRYCC	Epimerase domain-containing protein. (458 aa)
	Q4DXL5_TRYCC	Malate dehydrogenase. (318 aa)
	Q4DY23_TRYCC	Alcohol dehydrogenase, putative. (392 aa)
	Q4DY29_TRYCC	GDP-L-fucose synthetase, putative. (317 aa)
	Q4DZU3_TRYCC	UDP-glucose 6-dehydrogenase. (501 aa)
	Q4E0B2_TRYCC	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (555 aa)
	GMPR-2	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (491 aa)
	Q4E4L7_TRYCC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
	Q4E5I9_TRYCC	Alcohol dehydrogenase, putative. (392 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGFS_TRYCC	Q4CSB2_TRYCC	Q4DJ07	Q4CSB2	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	NADP-dependent alcohol hydrogenase, putative.	0.434
PGFS_TRYCC	Q4CU50_TRYCC	Q4DJ07	Q4CU50	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative.	0.695
PGFS_TRYCC	Q4CU51_TRYCC	Q4DJ07	Q4CU51	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative.	0.695
PGFS_TRYCC	Q4CU52_TRYCC	Q4DJ07	Q4CU52	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative.	0.695
PGFS_TRYCC	Q4D0X5_TRYCC	Q4DJ07	Q4D0X5	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.411
PGFS_TRYCC	Q4D2W4_TRYCC	Q4DJ07	Q4D2W4	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	6-phosphogluconate dehydrogenase, decarboxylating, putative.	0.411
PGFS_TRYCC	Q4DAE1_TRYCC	Q4DJ07	Q4DAE1	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	D-isomer specific 2-hydroxyacid dehydrogenase-protein, putative.	0.695
PGFS_TRYCC	Q4DEF3_TRYCC	Q4DJ07	Q4DEF3	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	NADP-dependent alcohol hydrogenase, putative.	0.434
PGFS_TRYCC	Q4DFP0_TRYCC	Q4DJ07	Q4DFP0	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	NADP-dependent alcohol hydrogenase, putative.	0.434
PGFS_TRYCC	Q4DU92_TRYCC	Q4DJ07	Q4DU92	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	6-phosphogluconate dehydrogenase, decarboxylating.	0.411
PGFS_TRYCC	Q4DY23_TRYCC	Q4DJ07	Q4DY23	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	Alcohol dehydrogenase, putative.	0.589
PGFS_TRYCC	Q4E5I9_TRYCC	Q4DJ07	Q4E5I9	9,11-endoperoxide prostaglandin H2 reductase; Catalyzes the NADP-dependent formation of prostaglandin F2- alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p- nitrobenzaldehyde.	Alcohol dehydrogenase, putative.	0.589
Q4CL61_TRYCC	Q4CR34_TRYCC	Q4CL61	Q4CR34	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	Uncharacterized protein.	0.401
Q4CL61_TRYCC	Q4CSB2_TRYCC	Q4CL61	Q4CSB2	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	NADP-dependent alcohol hydrogenase, putative.	0.431
Q4CL61_TRYCC	Q4DBK7_TRYCC	Q4CL61	Q4DBK7	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	Uncharacterized protein.	0.401
Q4CL61_TRYCC	Q4DEF3_TRYCC	Q4CL61	Q4DEF3	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	NADP-dependent alcohol hydrogenase, putative.	0.431
Q4CL61_TRYCC	Q4DFP0_TRYCC	Q4CL61	Q4DFP0	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	NADP-dependent alcohol hydrogenase, putative.	0.431
Q4CL61_TRYCC	Q4DGX8_TRYCC	Q4CL61	Q4DGX8	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	Uncharacterized protein.	0.401
Q4CL61_TRYCC	Q4DSB7_TRYCC	Q4CL61	Q4DSB7	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	Uncharacterized protein.	0.401
Q4CL61_TRYCC	Q4DY23_TRYCC	Q4CL61	Q4DY23	3,2-trans-enoyl-coA isomerase, mitochondrial, putative.	Alcohol dehydrogenase, putative.	0.424