39 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4D7D8_TRYCC	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (461 aa)
	Q4CM74_TRYCC	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (265 aa)
	Q4CQW5_TRYCC	Fumarate hydratase, putative. (555 aa)
	Q4CR18_TRYCC	Glutamate dehydrogenase, putative. (383 aa)
	Q4CRK6_TRYCC	Aspartate aminotransferase. (404 aa)
	Q4CTR7_TRYCC	Malate dehydrogenase. (332 aa)
	Q4CVA1_TRYCC	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (566 aa)
	Q4CVH4_TRYCC	Glutamate dehydrogenase, putative. (211 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa)
	Q4D080_TRYCC	Aspartate aminotransferase. (404 aa)
	Q4D123_TRYCC	Malate dehydrogenase. (332 aa)
	Q4D1Q4_TRYCC	Aspartate aminotransferase, mitochondrial, putative. (418 aa)
	Q4D4A0_TRYCC	Malate dehydrogenase. (301 aa)
	Q4D4A1_TRYCC	Malate dehydrogenase. (374 aa)
	Q4D5C2_TRYCC	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
	Q4DAI0_TRYCC	Aminoacylase, putative. (401 aa)
	Q4DAI1_TRYCC	Aminoacylase, putative. (189 aa)
	Q4DAI2_TRYCC	Aminoacylase, putative. (396 aa)
	Q4DDK8_TRYCC	Glycosomal malate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (323 aa)
	Q4DGW6_TRYCC	Aminoacylase, putative. (396 aa)
	Q4DGW7_TRYCC	Aminoacylase, putative. (106 aa)
	Q4DGW8_TRYCC	Aminoacylase, putative. (401 aa)
	Q4DIU8_TRYCC	Uncharacterized protein. (519 aa)
	Q4DJ68_TRYCC	Malic enzyme. (565 aa)
	Q4DJ69_TRYCC	Malic enzyme. (573 aa)
	Q4DJH1_TRYCC	Fumarate hydratase, putative. (565 aa)
	KYNU-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa)
	Q4DRD8_TRYCC	Glycosomal malate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (323 aa)
	Q4DRT8_TRYCC	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (561 aa)
	Q4DRX1_TRYCC	Fumarate hydratase, putative. (555 aa)
	Q4DSP9_TRYCC	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (461 aa)
	Q4DV36_TRYCC	Malic enzyme. (565 aa)
	Q4DV37_TRYCC	Malic enzyme. (573 aa)
	Q4DWV8_TRYCC	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
	Q4DXL5_TRYCC	Malate dehydrogenase. (318 aa)
	Q4DY23_TRYCC	Alcohol dehydrogenase, putative. (392 aa)
	Q4DYS1_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (504 aa)
	Q4E3I6_TRYCC	Fumarate hydratase, putative. (565 aa)
	Q4E5I9_TRYCC	Alcohol dehydrogenase, putative. (392 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KYNU	KYNU-2	Q4CYC0	Q4DQ63	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.900
KYNU-2	KYNU	Q4DQ63	Q4CYC0	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.900
Q4CM74_TRYCC	Q4CQW5_TRYCC	Q4CM74	Q4CQW5	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Fumarate hydratase, putative.	0.446
Q4CM74_TRYCC	Q4CR18_TRYCC	Q4CM74	Q4CR18	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Glutamate dehydrogenase, putative.	0.471
Q4CM74_TRYCC	Q4CRK6_TRYCC	Q4CM74	Q4CRK6	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Aspartate aminotransferase.	0.617
Q4CM74_TRYCC	Q4CVA1_TRYCC	Q4CM74	Q4CVA1	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.966
Q4CM74_TRYCC	Q4CVH4_TRYCC	Q4CM74	Q4CVH4	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Glutamate dehydrogenase, putative.	0.471
Q4CM74_TRYCC	Q4D080_TRYCC	Q4CM74	Q4D080	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Aspartate aminotransferase.	0.617
Q4CM74_TRYCC	Q4D1Q4_TRYCC	Q4CM74	Q4D1Q4	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Aspartate aminotransferase, mitochondrial, putative.	0.632
Q4CM74_TRYCC	Q4D5C2_TRYCC	Q4CM74	Q4D5C2	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.457
Q4CM74_TRYCC	Q4D7D8_TRYCC	Q4CM74	Q4D7D8	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.618
Q4CM74_TRYCC	Q4DJ68_TRYCC	Q4CM74	Q4DJ68	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Malic enzyme.	0.423
Q4CM74_TRYCC	Q4DJ69_TRYCC	Q4CM74	Q4DJ69	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Malic enzyme.	0.423
Q4CM74_TRYCC	Q4DJH1_TRYCC	Q4CM74	Q4DJH1	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Fumarate hydratase, putative.	0.446
Q4CM74_TRYCC	Q4DRX1_TRYCC	Q4CM74	Q4DRX1	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Fumarate hydratase, putative.	0.446
Q4CM74_TRYCC	Q4DSP9_TRYCC	Q4CM74	Q4DSP9	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.618
Q4CM74_TRYCC	Q4DV36_TRYCC	Q4CM74	Q4DV36	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Malic enzyme.	0.423
Q4CM74_TRYCC	Q4DV37_TRYCC	Q4CM74	Q4DV37	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Malic enzyme.	0.423
Q4CM74_TRYCC	Q4DWV8_TRYCC	Q4CM74	Q4DWV8	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.457
Q4CM74_TRYCC	Q4DY23_TRYCC	Q4CM74	Q4DY23	Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	Alcohol dehydrogenase, putative.	0.735