112 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4CVD1_TRYCC	Uncharacterized protein. (262 aa)
	Q4CWE0_TRYCC	CNH domain-containing protein. (854 aa)
	Q4CX12_TRYCC	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (746 aa)
	Q4CX75_TRYCC	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (417 aa)
	Q4CXL5_TRYCC	Uncharacterized protein. (143 aa)
	Q4CXX0_TRYCC	Uncharacterized protein. (428 aa)
	Q4CXY9_TRYCC	Syntaxin, putative. (229 aa)
	Q4CY34_TRYCC	Uncharacterized protein. (443 aa)
	Q4CYA3_TRYCC	GB1/RHD3-type G domain-containing protein. (410 aa)
	Q4CYJ1_TRYCC	Target SNARE, putative. (316 aa)
	Q4CYY0_TRYCC	RING-type domain-containing protein. (1332 aa)
	Q4CZ64_TRYCC	Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (229 aa)
	Q4CZQ1_TRYCC	Vesicle-associated membrane protein, putative; Belongs to the syntaxin family. (297 aa)
	Q4D090_TRYCC	Syntaxin, putative. (260 aa)
	Q4D0M7_TRYCC	Uncharacterized protein. (219 aa)
	Q4D1R8_TRYCC	Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (344 aa)
	Q4D318_TRYCC	Small GTP-binding protein, putative; Belongs to the small GTPase superfamily. SAR1 family. (194 aa)
	Q4D3C4_TRYCC	Nonspecific lipid-transfer protein, putative. (264 aa)
	Q4D434_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa)
	Q4CNX7_TRYCC	SNARE protein, putative. (237 aa)
	Q4D450_TRYCC	Uncharacterized protein. (227 aa)
	Q4D470_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (337 aa)
	Q4CNP5_TRYCC	Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (577 aa)
	ASNA_TRYCC	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (359 aa)
	Q4CMQ3_TRYCC	Phospholipid-transporting ATPase, putative. (273 aa)
	Q4CMH5_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (75 aa)
	Q4CMH4_TRYCC	DUF2012 domain-containing protein. (254 aa)
	Q4CMD6_TRYCC	ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. SAR1 family. (164 aa)
	Q4CM93_TRYCC	Syntaxin, putative. (266 aa)
	Q4CL59_TRYCC	Vacuolar assembly protein vps41, putative. (569 aa)
	Q4CKP6_TRYCC	Uncharacterized protein. (413 aa)
	Q4D4K7_TRYCC	Uncharacterized protein. (107 aa)
	Q4D4Z2_TRYCC	J domain-containing protein. (777 aa)
	Q4D518_TRYCC	Sec16_C domain-containing protein. (1482 aa)
	Q4D5N6_TRYCC	ER membrane protein complex subunit 3. (242 aa)
	Q4D5R9_TRYCC	CNH domain-containing protein. (989 aa)
	Q4D5U9_TRYCC	ER membrane protein complex subunit 3. (242 aa)
	Q4D6B0_TRYCC	RING-type domain-containing protein. (1815 aa)
	Q4D6I2_TRYCC	CNH domain-containing protein. (969 aa)
	Q4D726_TRYCC	Golgi SNARE protein-like, putative. (238 aa)
	Q4D7P4_TRYCC	Uncharacterized protein. (434 aa)
	Q4D890_TRYCC	Paraflagellar rod protein, putative. (195 aa)
	Q4D8X0_TRYCC	Target SNARE, putative. (316 aa)
	Q4D911_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1356 aa)
	Q4D922_TRYCC	DUF3395 domain-containing protein. (396 aa)
	Q4D942_TRYCC	Vacuolar assembly protein vps41, putative. (291 aa)
	Q4D9H5_TRYCC	Uncharacterized protein. (540 aa)
	Q4DC34_TRYCC	CNH domain-containing protein. (309 aa)
	Q4DCA3_TRYCC	Vesicle-associated membrane protein, putative; Belongs to the syntaxin family. (297 aa)
	Q4DCG0_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (286 aa)
	Q4DCM5_TRYCC	CRAL-TRIO domain-containing protein. (523 aa)
	Q4DEU2_TRYCC	Vacuolar assembly protein vps41, putative. (134 aa)
	Q4DF21_TRYCC	Syntaxin, putative. (302 aa)
	Q4DFA3_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (237 aa)
	Q4DFA4_TRYCC	DUF2012 domain-containing protein. (257 aa)
	Q4DFI8_TRYCC	CRAL-TRIO domain-containing protein. (301 aa)
	Q4DG63_TRYCC	Protein transport protein Sec23, putative. (998 aa)
	Q4DGD2_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa)
	SEY1_TRYCC	Protein SEY1 homolog; Probable GTP-binding protein that may be involved in cell development; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (877 aa)
	Q4DHQ6_TRYCC	Golgi vesicular membrane trafficking protein, putative. (121 aa)
	Q4DHU5_TRYCC	Syntaxin, putative. (302 aa)
	Q4DIZ3_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (237 aa)
	Q4DK29_TRYCC	Syntaxin 5, putative. (330 aa)
	Q4DK31_TRYCC	Protein transport protein sec13, putative; Belongs to the WD repeat SEC13 family. (376 aa)
	Q4DKL0_TRYCC	Sec16_C domain-containing protein. (1482 aa)
	Q4DKZ2_TRYCC	SNF-7-like protein, putative. (221 aa)
	Q4DL81_TRYCC	TPR_REGION domain-containing protein. (315 aa)
	Q4DLE8_TRYCC	Uncharacterized protein. (1141 aa)
	Q4DMJ0_TRYCC	Protein transport protein sec13, putative; Belongs to the WD repeat SEC13 family. (322 aa)
	Q4DMW3_TRYCC	CNH domain-containing protein. (989 aa)
	Q4DNQ2_TRYCC	Uncharacterized protein. (227 aa)
	Q4DNY3_TRYCC	Paraflagellar rod protein, putative. (741 aa)
	Q4DP28_TRYCC	Vesicle-associated membrane protein, putative; Belongs to the synaptobrevin family. (205 aa)
	Q4DPI7_TRYCC	TPR_REGION domain-containing protein. (315 aa)
	Q4DPV1_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1259 aa)
	Q4DR29_TRYCC	Uncharacterized protein. (117 aa)
	Q4DRE9_TRYCC	Uncharacterized protein. (215 aa)
	Q4DRI6_TRYCC	Uncharacterized protein. (219 aa)
	Q4DS29_TRYCC	Uncharacterized protein. (1140 aa)
	Q4DS88_TRYCC	Vesicle-associated membrane protein, putative; Belongs to the synaptobrevin family. (205 aa)
	Q4DSA9_TRYCC	Uncharacterized protein. (507 aa)
	Q4DSB3_TRYCC	Vesicle transport v-SNARE 11, putative. (234 aa)
	Q4DSB4_TRYCC	Vesicle transport v-SNARE 11, putative. (278 aa)
	Q4DST2_TRYCC	Arf-GAP domain-containing protein. (318 aa)
	Q4DT76_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1217 aa)
	Q4DTI7_TRYCC	EMC1_C domain-containing protein. (809 aa)
	Q4DU40_TRYCC	Arf-GAP domain-containing protein. (318 aa)
	Q4DUB4_TRYCC	CRAL-TRIO domain-containing protein. (301 aa)
	Q4DVU8_TRYCC	CRAL-TRIO domain-containing protein. (316 aa)
	Q4DW51_TRYCC	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (220 aa)
	Q4DWA2_TRYCC	Golgi vesicular membrane trafficking protein, putative. (121 aa)
	Q4DXI9_TRYCC	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1217 aa)
	Q4DXS9_TRYCC	Golgi SNARE protein-like, putative. (238 aa)
	Q4DYJ5_TRYCC	t-SNARE coiled-coil homology domain-containing protein. (320 aa)
	Q4DZ79_TRYCC	CRAL-TRIO domain-containing protein. (292 aa)
	Q4E0C4_TRYCC	Clathrin coat assembly protein, putative. (500 aa)
	Q4E0N8_TRYCC	Uncharacterized protein. (428 aa)
	Q4E0U6_TRYCC	Uncharacterized protein. (143 aa)
	Q4E1B5_TRYCC	SEP domain-containing protein. (339 aa)
	Q4E2V6_TRYCC	Syntaxin 5, putative. (330 aa)
	Q4E2V8_TRYCC	Protein transport protein sec13, putative; Belongs to the WD repeat SEC13 family. (376 aa)
	Q4E4A5_TRYCC	F-box domain-containing protein. (1150 aa)
	Q4E571_TRYCC	MSP domain-containing protein. (234 aa)
	Q4CU37_TRYCC	Vacuolar assembly protein vps41, putative. (1084 aa)
	Q4CVD2_TRYCC	V-SNARE domain-containing protein. (278 aa)
	Q4CPV9_TRYCC	MSP domain-containing protein. (234 aa)
	Q4CQ17_TRYCC	Bac_surface_Ag domain-containing protein. (479 aa)
	Q4CQX2_TRYCC	Bac_surface_Ag domain-containing protein. (479 aa)
	Q4CRX2_TRYCC	Clathrin coat assembly protein, putative. (500 aa)
	Q4CTS6_TRYCC	Syntaxin, putative. (260 aa)
	Q4CTX6_TRYCC	Uncharacterized protein. (540 aa)
	Q4CTY4_TRYCC	Protein transport protein Sec24C, putative. (276 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNA_TRYCC	Q4D4K7_TRYCC	Q4CNH2	Q4D4K7	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Uncharacterized protein.	0.550
ASNA_TRYCC	Q4D5N6_TRYCC	Q4CNH2	Q4D5N6	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	ER membrane protein complex subunit 3.	0.561
ASNA_TRYCC	Q4D5U9_TRYCC	Q4CNH2	Q4D5U9	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	ER membrane protein complex subunit 3.	0.561
ASNA_TRYCC	Q4DK29_TRYCC	Q4CNH2	Q4DK29	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Syntaxin 5, putative.	0.825
ASNA_TRYCC	Q4E2V6_TRYCC	Q4CNH2	Q4E2V6	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Syntaxin 5, putative.	0.825
Q4CKP6_TRYCC	Q4DST2_TRYCC	Q4CKP6	Q4DST2	Uncharacterized protein.	Arf-GAP domain-containing protein.	0.400
Q4CKP6_TRYCC	Q4DU40_TRYCC	Q4CKP6	Q4DU40	Uncharacterized protein.	Arf-GAP domain-containing protein.	0.400
Q4CL59_TRYCC	Q4CTS6_TRYCC	Q4CL59	Q4CTS6	Vacuolar assembly protein vps41, putative.	Syntaxin, putative.	0.631
Q4CL59_TRYCC	Q4CVD1_TRYCC	Q4CL59	Q4CVD1	Vacuolar assembly protein vps41, putative.	Uncharacterized protein.	0.643
Q4CL59_TRYCC	Q4CVD2_TRYCC	Q4CL59	Q4CVD2	Vacuolar assembly protein vps41, putative.	V-SNARE domain-containing protein.	0.643
Q4CL59_TRYCC	Q4CWE0_TRYCC	Q4CL59	Q4CWE0	Vacuolar assembly protein vps41, putative.	CNH domain-containing protein.	0.599
Q4CL59_TRYCC	Q4D090_TRYCC	Q4CL59	Q4D090	Vacuolar assembly protein vps41, putative.	Syntaxin, putative.	0.631
Q4CL59_TRYCC	Q4D5R9_TRYCC	Q4CL59	Q4D5R9	Vacuolar assembly protein vps41, putative.	CNH domain-containing protein.	0.599
Q4CL59_TRYCC	Q4D6I2_TRYCC	Q4CL59	Q4D6I2	Vacuolar assembly protein vps41, putative.	CNH domain-containing protein.	0.599
Q4CL59_TRYCC	Q4DC34_TRYCC	Q4CL59	Q4DC34	Vacuolar assembly protein vps41, putative.	CNH domain-containing protein.	0.599
Q4CL59_TRYCC	Q4DIZ3_TRYCC	Q4CL59	Q4DIZ3	Vacuolar assembly protein vps41, putative.	t-SNARE coiled-coil homology domain-containing protein.	0.631
Q4CL59_TRYCC	Q4DMW3_TRYCC	Q4CL59	Q4DMW3	Vacuolar assembly protein vps41, putative.	CNH domain-containing protein.	0.599
Q4CL59_TRYCC	Q4DP28_TRYCC	Q4CL59	Q4DP28	Vacuolar assembly protein vps41, putative.	Vesicle-associated membrane protein, putative; Belongs to the synaptobrevin family.	0.781
Q4CL59_TRYCC	Q4DS88_TRYCC	Q4CL59	Q4DS88	Vacuolar assembly protein vps41, putative.	Vesicle-associated membrane protein, putative; Belongs to the synaptobrevin family.	0.781
Q4CL59_TRYCC	Q4DSA9_TRYCC	Q4CL59	Q4DSA9	Vacuolar assembly protein vps41, putative.	Uncharacterized protein.	0.599