(41 nodes) Carboxy-terminal domain protein kinase complex network (Trypanosoma cruzi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4DH85_TRYCC	Protein kinase, putative. (1647 aa)
	Q4D326_TRYCC	Helicase-like protein, putative. (953 aa)
	Q4D2J9_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4DCW6_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4DF08_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4CVA8_TRYCC	Helicase-like protein, putative. (837 aa)
	Q4CW45_TRYCC	Protein kinase, putative. (403 aa)
	Q4CWS7_TRYCC	Uncharacterized protein. (602 aa)
	Q4CYH2_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4CZ36_TRYCC	TFIIH basal transcription factor complex helicase subunit, putative. (804 aa)
	Q4D1Y3_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4E2L5_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4E0I1_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4E0H6_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4DZD5_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4DZD0_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4DY61_TRYCC	DNA repair and transcription factor protein, putative. (356 aa)
	Q4DY33_TRYCC	Cyclin 9, putative. (280 aa)
	Q4DVN7_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4DRP6_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4DRM6_TRYCC	Protein kinase, putative. (786 aa)
	Q4DC69_TRYCC	Protein kinase, putative. (403 aa)
	Q4D9N4_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4D8X8_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4D8Q9_TRYCC	Protein kinase, putative. (339 aa)
	Q4D8C5_TRYCC	DNA repair helicase and transcription factor protein, putative. (925 aa)
	Q4DCU9_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4D8B2_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4D838_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4DM60_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (220 aa)
	Q4DKL9_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4E3H3_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (339 aa)
	Q4E401_TRYCC	Protein kinase, putative. (788 aa)
	Q4DI73_TRYCC	Kinase, putative. (177 aa)
	Q4DHR0_TRYCC	DNA repair helicase and transcription factor protein, putative. (925 aa)
	Q4CTB9_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (312 aa)
	Q4CRF3_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)
	Q4CMV3_TRYCC	TFIIH basal transcription factor complex helicase subunit, putative. (452 aa)
	Q4CLX8_TRYCC	Protein kinase, putative; Belongs to the protein kinase superfamily. (338 aa)
	Q4D5K3_TRYCC	DNA repair helicase, putative. (778 aa)
	Q4D3P9_TRYCC	Protein kinase, putative. (933 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CLX8_TRYCC	Q4CMV3_TRYCC	Q4CLX8	Q4CMV3	Protein kinase, putative; Belongs to the protein kinase superfamily.	TFIIH basal transcription factor complex helicase subunit, putative.	0.548
Q4CLX8_TRYCC	Q4CZ36_TRYCC	Q4CLX8	Q4CZ36	Protein kinase, putative; Belongs to the protein kinase superfamily.	TFIIH basal transcription factor complex helicase subunit, putative.	0.548
Q4CLX8_TRYCC	Q4D5K3_TRYCC	Q4CLX8	Q4D5K3	Protein kinase, putative; Belongs to the protein kinase superfamily.	DNA repair helicase, putative.	0.492
Q4CLX8_TRYCC	Q4D8C5_TRYCC	Q4CLX8	Q4D8C5	Protein kinase, putative; Belongs to the protein kinase superfamily.	DNA repair helicase and transcription factor protein, putative.	0.492
Q4CLX8_TRYCC	Q4DHR0_TRYCC	Q4CLX8	Q4DHR0	Protein kinase, putative; Belongs to the protein kinase superfamily.	DNA repair helicase and transcription factor protein, putative.	0.492
Q4CLX8_TRYCC	Q4DY61_TRYCC	Q4CLX8	Q4DY61	Protein kinase, putative; Belongs to the protein kinase superfamily.	DNA repair and transcription factor protein, putative.	0.698
Q4CMV3_TRYCC	Q4CLX8_TRYCC	Q4CMV3	Q4CLX8	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4CRF3_TRYCC	Q4CMV3	Q4CRF3	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4CTB9_TRYCC	Q4CMV3	Q4CTB9	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4CYH2_TRYCC	Q4CMV3	Q4CYH2	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4CZ36_TRYCC	Q4CMV3	Q4CZ36	TFIIH basal transcription factor complex helicase subunit, putative.	TFIIH basal transcription factor complex helicase subunit, putative.	0.900
Q4CMV3_TRYCC	Q4D1Y3_TRYCC	Q4CMV3	Q4D1Y3	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4D2J9_TRYCC	Q4CMV3	Q4D2J9	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4D5K3_TRYCC	Q4CMV3	Q4D5K3	TFIIH basal transcription factor complex helicase subunit, putative.	DNA repair helicase, putative.	0.967
Q4CMV3_TRYCC	Q4D838_TRYCC	Q4CMV3	Q4D838	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4D8B2_TRYCC	Q4CMV3	Q4D8B2	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4D8C5_TRYCC	Q4CMV3	Q4D8C5	TFIIH basal transcription factor complex helicase subunit, putative.	DNA repair helicase and transcription factor protein, putative.	0.967
Q4CMV3_TRYCC	Q4D8Q9_TRYCC	Q4CMV3	Q4D8Q9	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative.	0.548
Q4CMV3_TRYCC	Q4D8X8_TRYCC	Q4CMV3	Q4D8X8	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548
Q4CMV3_TRYCC	Q4D9N4_TRYCC	Q4CMV3	Q4D9N4	TFIIH basal transcription factor complex helicase subunit, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.548