(84 nodes) ATPase, AAA-type, core network (Trypanosoma cruzi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4CLP1_TRYCC	ATP-dependent Clp protease subunit, heat shock protein 100, putative. (256 aa)
	Q4CNM5_TRYCC	ATP-dependent Clp protease subunit, heat shock protein 100 (HSP100), putative. (603 aa)
	Q4CNM9_TRYCC	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family. (127 aa)
	Q4CRW0_TRYCC	ATP-dependent Clp protease subunit, heat shock protein 78, putative. (368 aa)
	Q4CSQ7_TRYCC	Peroxisome assembly protein, putative. (873 aa)
	Q4CVL6_TRYCC	AAA ATPase, putative. (783 aa)
	Q4CWN3_TRYCC	Replication factor C, subunit 2, putative. (347 aa)
	Q4CXI9_TRYCC	Katanin, putative; Belongs to the AAA ATPase family. (239 aa)
	Q4CYY6_TRYCC	ATPase domain protein, putative; Belongs to the AAA ATPase family. (534 aa)
	Q4CZ68_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (487 aa)
	Q4D0B1_TRYCC	ATP-dependent chaperone, putative; Belongs to the AAA ATPase family. (468 aa)
	Q4D0B9_TRYCC	Proteasome regulatory ATPase subunit 2, putative; Belongs to the AAA ATPase family. (437 aa)
	Q4D0R7_TRYCC	Vesicular-fusion ATPase-like protein, putative. (880 aa)
	Q4D0R9_TRYCC	Vesicular transport protein (CDC48 homologue), putative. (162 aa)
	Q4D2L7_TRYCC	ATPase_AAA_core domain-containing protein. (1187 aa)
	Q4D2V5_TRYCC	Replication factor C, subunit 3, putative. (355 aa)
	Q4D3U6_TRYCC	ATP-dependent chaperone, putative; Belongs to the AAA ATPase family. (468 aa)
	Q4D459_TRYCC	Replication factor C, subunit 4, putative. (144 aa)
	Q4D4L1_TRYCC	Cell division cycle protein, putative. (658 aa)
	Q4D4Y6_TRYCC	Katanin-like protein, putative; Belongs to the AAA ATPase family. (923 aa)
	Q4D5H5_TRYCC	Cell division cycle protein, putative. (737 aa)
	Q4D5M4_TRYCC	Peroxisome biogenesis factor 1, putative. (913 aa)
	Q4D5R2_TRYCC	Vesicle-fusing ATPase, putative. (726 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (592 aa)
	Q4D6V7_TRYCC	AAA domain-containing protein. (673 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (558 aa)
	Q4D903_TRYCC	AAA domain-containing protein. (448 aa)
	Q4D9C2_TRYCC	Katanin, putative. (211 aa)
	Q4D9H9_TRYCC	ATP-dependent chaperone, putative. (537 aa)
	Q4D9J1_TRYCC	Proteasome regulatory ATPase subunit 1, putative; Belongs to the AAA ATPase family. (437 aa)
	Q4D9R1_TRYCC	Vesicle-fusing ATPase, putative. (726 aa)
	Q4DA27_TRYCC	Peroxisome assembly protein, putative. (955 aa)
	Q4DAV1_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative. (712 aa)
	Q4DB43_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (520 aa)
	Q4DBP0_TRYCC	ATP-dependent zinc metallopeptidase, putative. (891 aa)
	Q4DDA7_TRYCC	AAA domain-containing protein. (1008 aa)
	Q4DDZ4_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (339 aa)
	Q4DEP1_TRYCC	Heat shock protein HslVU, ATPase subunit HslU, putative. (474 aa)
	Q4DEY4_TRYCC	ATP-dependent zinc metallopeptidase, putative; Belongs to the AAA ATPase family. (683 aa)
	Q4DFA0_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (339 aa)
	Q4DFV8_TRYCC	Vesicular transport protein (CDC48 homologue), putative; Belongs to the AAA ATPase family. (248 aa)
	Q4DH19_TRYCC	ATPase, putative. (628 aa)
	Q4DHH6_TRYCC	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family. (398 aa)
	KATNAL2-2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (588 aa)
	Q4DJU4_TRYCC	ATP-dependent zinc metallopeptidase, putative; Belongs to the AAA ATPase family. (682 aa)
	KATNA1-2	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (681 aa)
	Q4DM81_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (576 aa)
	Q4DMG4_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative; Belongs to the AAA ATPase family. (657 aa)
	Q4DMU3_TRYCC	Replication factor C, subunit 2, putative. (347 aa)
	Q4DNR1_TRYCC	Replication factor C, subunit 4, putative. (340 aa)
	Q4DNT6_TRYCC	Vacuolar transport protein 4A, putative; Belongs to the AAA ATPase family. (448 aa)
	Q4DQD6_TRYCC	Vesicular transport protein (CDC48 homologue), putative; Belongs to the AAA ATPase family. (663 aa)
	Q4DQD8_TRYCC	Vesicular-fusion ATPase-like protein, putative. (880 aa)
	Q4DRN5_TRYCC	Heat shock protein HslVU, ATPase subunit HslU, putative. (490 aa)
	Q4DRV9_TRYCC	ATPase domain protein, putative; Belongs to the AAA ATPase family. (572 aa)
	Q4DS46_TRYCC	ATPase_AAA_core domain-containing protein. (1185 aa)
	Q4DSH8_TRYCC	AAA domain-containing protein. (945 aa)
	Q4DTF6_TRYCC	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family. (398 aa)
	Q4DTH5_TRYCC	ATP-dependent Clp protease subunit, heat shock protein 78, putative. (802 aa)
	Q4DTN1_TRYCC	AAA domain-containing protein. (644 aa)
	KATNA1-3	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (681 aa)
	Q4DTV3_TRYCC	Peroxisome biogenesis factor 1, putative. (913 aa)
	Q4DTY3_TRYCC	AAA ATPase, putative. (876 aa)
	Q4DUG6_TRYCC	Replication factor C, subunit 3, putative. (355 aa)
	Q4DV91_TRYCC	AAA ATPase, putative. (877 aa)
	Q4DVH1_TRYCC	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family. (441 aa)
	Q4DVU0_TRYCC	AAA domain-containing protein; Belongs to the AAA ATPase family. (520 aa)
	Q4DW08_TRYCC	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family. (403 aa)
	Q4DW61_TRYCC	ATPase, putative. (628 aa)
	Q4DWB5_TRYCC	Transitional endoplasmic reticulum ATPase, putative. (778 aa)
	Q4DWK0_TRYCC	AAA ATPase, putative. (1214 aa)
	Q4DXC6_TRYCC	ATPase protein, putative; Belongs to the AAA ATPase family. (618 aa)
	Q4DYA7_TRYCC	AAA domain-containing protein. (673 aa)
	Q4DZM5_TRYCC	Proteasome regulatory ATPase subunit, putative; Belongs to the AAA ATPase family. (404 aa)
	Q4DZT3_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative; Belongs to the AAA ATPase family. (657 aa)
	Q4E0K2_TRYCC	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family. (403 aa)
	Q4E0Q8_TRYCC	ATPase, putative. (1236 aa)
	Q4E1K2_TRYCC	AAA domain-containing protein. (1008 aa)
	Q4E303_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative. (712 aa)
	Q4E408_TRYCC	Heat shock protein HslVU, ATPase subunit HslU, putative. (490 aa)
	Q4E4K9_TRYCC	ATPase, putative. (667 aa)
	Q4E554_TRYCC	AAA ATPase, putative. (1214 aa)
	Q4E5H7_TRYCC	ATP-dependent zinc metallopeptidase, putative; Belongs to the AAA ATPase family. (564 aa)
	Q4E658_TRYCC	Katanin-like protein, putative; Belongs to the AAA ATPase family. (444 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KATNA1	Q4CNM9_TRYCC	Q4D731	Q4CNM9	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.718
KATNA1	Q4CYY6_TRYCC	Q4D731	Q4CYY6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	ATPase domain protein, putative; Belongs to the AAA ATPase family.	0.405
KATNA1	Q4D4L1_TRYCC	Q4D731	Q4D4L1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Cell division cycle protein, putative.	0.403
KATNA1	Q4DHH6_TRYCC	Q4D731	Q4DHH6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.546
KATNA1	Q4DRV9_TRYCC	Q4D731	Q4DRV9	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	ATPase domain protein, putative; Belongs to the AAA ATPase family.	0.406
KATNA1	Q4DTF6_TRYCC	Q4D731	Q4DTF6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.546
KATNA1	Q4DVH1_TRYCC	Q4D731	Q4DVH1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.560
KATNA1	Q4DW08_TRYCC	Q4D731	Q4DW08	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.539
KATNA1	Q4E0K2_TRYCC	Q4D731	Q4E0K2	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.538
KATNA1-2	Q4CNM9_TRYCC	Q4DLN7	Q4CNM9	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.558
KATNA1-2	Q4CYY6_TRYCC	Q4DLN7	Q4CYY6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	ATPase domain protein, putative; Belongs to the AAA ATPase family.	0.404
KATNA1-2	Q4D0R7_TRYCC	Q4DLN7	Q4D0R7	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Vesicular-fusion ATPase-like protein, putative.	0.405
KATNA1-2	Q4D4L1_TRYCC	Q4DLN7	Q4D4L1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Cell division cycle protein, putative.	0.412
KATNA1-2	Q4DH19_TRYCC	Q4DLN7	Q4DH19	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	ATPase, putative.	0.405
KATNA1-2	Q4DHH6_TRYCC	Q4DLN7	Q4DHH6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.548
KATNA1-2	Q4DQD8_TRYCC	Q4DLN7	Q4DQD8	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Vesicular-fusion ATPase-like protein, putative.	0.404
KATNA1-2	Q4DRV9_TRYCC	Q4DLN7	Q4DRV9	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	ATPase domain protein, putative; Belongs to the AAA ATPase family.	0.407
KATNA1-2	Q4DTF6_TRYCC	Q4DLN7	Q4DTF6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.548
KATNA1-2	Q4DVH1_TRYCC	Q4DLN7	Q4DVH1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.561
KATNA1-2	Q4DW08_TRYCC	Q4DLN7	Q4DW08	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.545