(29 nodes) AAA ATPase, AAA+ lid domain network (Trypanosoma cruzi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4DHH6_TRYCC	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family. (398 aa)
	KATNAL2-2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (588 aa)
	Q4DQD6_TRYCC	Vesicular transport protein (CDC48 homologue), putative; Belongs to the AAA ATPase family. (663 aa)
	Q4DQD8_TRYCC	Vesicular-fusion ATPase-like protein, putative. (880 aa)
	Q4DTF6_TRYCC	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family. (398 aa)
	Q4DTY3_TRYCC	AAA ATPase, putative. (876 aa)
	Q4DV91_TRYCC	AAA ATPase, putative. (877 aa)
	Q4DVH1_TRYCC	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family. (441 aa)
	Q4DW08_TRYCC	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family. (403 aa)
	Q4DWB5_TRYCC	Transitional endoplasmic reticulum ATPase, putative. (778 aa)
	Q4E0K2_TRYCC	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family. (403 aa)
	Q4E0Q8_TRYCC	ATPase, putative. (1236 aa)
	Q4E303_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative. (712 aa)
	Q4DZM5_TRYCC	Proteasome regulatory ATPase subunit, putative; Belongs to the AAA ATPase family. (404 aa)
	Q4CNM9_TRYCC	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family. (127 aa)
	Q4CSI8_TRYCC	Katanin-like protein, putative; Belongs to the AAA ATPase family. (158 aa)
	Q4CVL6_TRYCC	AAA ATPase, putative. (783 aa)
	Q4CXI9_TRYCC	Katanin, putative; Belongs to the AAA ATPase family. (239 aa)
	Q4D0B9_TRYCC	Proteasome regulatory ATPase subunit 2, putative; Belongs to the AAA ATPase family. (437 aa)
	Q4D0R7_TRYCC	Vesicular-fusion ATPase-like protein, putative. (880 aa)
	Q4D4Y6_TRYCC	Katanin-like protein, putative; Belongs to the AAA ATPase family. (923 aa)
	Q4D5R2_TRYCC	Vesicle-fusing ATPase, putative. (726 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (592 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (558 aa)
	Q4D9J1_TRYCC	Proteasome regulatory ATPase subunit 1, putative; Belongs to the AAA ATPase family. (437 aa)
	Q4D9R1_TRYCC	Vesicle-fusing ATPase, putative. (726 aa)
	Q4DAV1_TRYCC	Mitochondrial ATP-dependent zinc metallopeptidase, putative. (712 aa)
	Q4DBP0_TRYCC	ATP-dependent zinc metallopeptidase, putative. (891 aa)
	Q4DFV8_TRYCC	Vesicular transport protein (CDC48 homologue), putative; Belongs to the AAA ATPase family. (248 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KATNA1	Q4CNM9_TRYCC	Q4D731	Q4CNM9	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.718
KATNA1	Q4DHH6_TRYCC	Q4D731	Q4DHH6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.546
KATNA1	Q4DTF6_TRYCC	Q4D731	Q4DTF6	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.546
KATNA1	Q4DVH1_TRYCC	Q4D731	Q4DVH1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.560
KATNA1	Q4DW08_TRYCC	Q4D731	Q4DW08	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.539
KATNA1	Q4E0K2_TRYCC	Q4D731	Q4E0K2	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.538
KATNAL2	KATNAL2-2	Q4D5V3	Q4DIH8	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.741
KATNAL2	Q4CNM9_TRYCC	Q4D5V3	Q4CNM9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.930
KATNAL2	Q4DHH6_TRYCC	Q4D5V3	Q4DHH6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.930
KATNAL2	Q4DTF6_TRYCC	Q4D5V3	Q4DTF6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.930
KATNAL2	Q4DVH1_TRYCC	Q4D5V3	Q4DVH1	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.931
KATNAL2	Q4DW08_TRYCC	Q4D5V3	Q4DW08	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.929
KATNAL2	Q4E0K2_TRYCC	Q4D5V3	Q4E0K2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.929
KATNAL2	Q4E0Q8_TRYCC	Q4D5V3	Q4E0Q8	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	ATPase, putative.	0.428
KATNAL2-2	KATNAL2	Q4DIH8	Q4D5V3	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.741
KATNAL2-2	Q4CNM9_TRYCC	Q4DIH8	Q4CNM9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.931
KATNAL2-2	Q4DHH6_TRYCC	Q4DIH8	Q4DHH6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.930
KATNAL2-2	Q4DTF6_TRYCC	Q4DIH8	Q4DTF6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.	0.930
KATNAL2-2	Q4DVH1_TRYCC	Q4DIH8	Q4DVH1	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 5, putative; Belongs to the AAA ATPase family.	0.931
KATNAL2-2	Q4DW08_TRYCC	Q4DIH8	Q4DW08	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome regulatory ATPase subunit 3, putative; Belongs to the AAA ATPase family.	0.929