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pfk | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (485 aa) | ||||
Q4CNY1_TRYCC | Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (484 aa) | ||||
Q4CQ52_TRYCC | Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (646 aa) | ||||
Q4CR01_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (453 aa) | ||||
Q4CSB9_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (352 aa) | ||||
Q4CSC4_TRYCC | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (394 aa) | ||||
Q4CSE9_TRYCC | Protein phosphatase; Belongs to the PP2C family. (282 aa) | ||||
PURA2_TRYCC | Adenylosuccinate synthetase 2; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). (616 aa) | ||||
Q4CXU8_TRYCC | Protein phosphatase; Belongs to the PP2C family. (329 aa) | ||||
Q4CZ09_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (453 aa) | ||||
Q4D043_TRYCC | Protein phosphatase; Belongs to the PP2C family. (329 aa) | ||||
Q4D0A7_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa) | ||||
Q4D161_TRYCC | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1198 aa) | ||||
Q4D3A0_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (362 aa) | ||||
Q4D3Y2_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (252 aa) | ||||
Q4D434_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa) | ||||
Q4D526_TRYCC | Glutathione synthetase. (535 aa) | ||||
Q4D6K7_TRYCC | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (323 aa) | ||||
Q4D790_TRYCC | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (323 aa) | ||||
Q4D7R4_TRYCC | Glutathione synthetase. (535 aa) | ||||
Q4D911_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1356 aa) | ||||
Q4D9Z4_TRYCC | Pyruvate kinase; Belongs to the pyruvate kinase family. (499 aa) | ||||
Q4DA33_TRYCC | Phosphoacetylglucosamine mutase. (610 aa) | ||||
Q4DA83_TRYCC | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (645 aa) | ||||
Q4DAY4_TRYCC | Inositol-1-monophosphatase. (363 aa) | ||||
ITPA1_TRYCC | Inosine triphosphate pyrophosphatase 1; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa) | ||||
Q4DDS8_TRYCC | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (401 aa) | ||||
Q4DE37_TRYCC | Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (898 aa) | ||||
Q4DEE6_TRYCC | Phosphomannomutase-like protein, putative; Belongs to the phosphohexose mutase family. (585 aa) | ||||
Q4DG65_TRYCC | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa) | ||||
Q4DG77_TRYCC | Protein phosphatase; Belongs to the PP2C family. (281 aa) | ||||
Q4DGA3_TRYCC | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (221 aa) | ||||
Q4DGD2_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1099 aa) | ||||
Q4DGE8_TRYCC | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1004 aa) | ||||
Q4DGU4_TRYCC | Protein phosphatase; Belongs to the PP2C family. (363 aa) | ||||
Q4DHI5_TRYCC | Phosphoacetylglucosamine mutase. (610 aa) | ||||
Q4DHP2_TRYCC | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (506 aa) | ||||
Q4DK98_TRYCC | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1246 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (393 aa) | ||||
Q4DL91_TRYCC | PPM-type phosphatase domain-containing protein. (1576 aa) | ||||
Q4DLI9_TRYCC | Phosphoglucomutase, putative; Belongs to the phosphohexose mutase family. (600 aa) | ||||
PURA1_TRYCC | Adenylosuccinate synthetase 1; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). (616 aa) | ||||
Q4DNU8_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (533 aa) | ||||
Q4DPN0_TRYCC | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (522 aa) | ||||
Q4DPS5_TRYCC | Inositol-1-monophosphatase. (283 aa) | ||||
Q4DPV1_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1259 aa) | ||||
Q4DQV0_TRYCC | Phosphoglucomutase, putative; Belongs to the phosphohexose mutase family. (600 aa) | ||||
Q4DRC4_TRYCC | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (241 aa) | ||||
ITPA2_TRYCC | Inosine triphosphate pyrophosphatase 2; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa) | ||||
Q4DSF6_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1143 aa) | ||||
Q4DSM1_TRYCC | PPM-type phosphatase domain-containing protein. (1576 aa) | ||||
Q4DT76_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1217 aa) | ||||
Q4DU82_TRYCC | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (672 aa) | ||||
Q4DW49_TRYCC | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (418 aa) | ||||
Q4DX52_TRYCC | Phosphomannomutase-like protein, putative; Belongs to the phosphohexose mutase family. (585 aa) | ||||
Q4DXI9_TRYCC | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1217 aa) | ||||
Q4DXT8_TRYCC | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1207 aa) | ||||
Q4DZ98_TRYCC | Enolase, putative. (429 aa) | ||||
Q4DZU4_TRYCC | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1006 aa) | ||||
Q4E0Q0_TRYCC | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (913 aa) | ||||
Q4E1U3_TRYCC | Pyruvate kinase; Belongs to the pyruvate kinase family. (499 aa) | ||||
Q4E3P5_TRYCC | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (913 aa) | ||||
Q4E4K4_TRYCC | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (330 aa) | ||||
Q4E4L7_TRYCC | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa) | ||||
Q4E4N2_TRYCC | Protein phosphatase, putative. (407 aa) | ||||
Q4E575_TRYCC | Protein phosphatase 2C, putative. (286 aa) | ||||
Q4E576_TRYCC | Protein phosphatase 2C, putative. (316 aa) | ||||
TRS | Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family. (647 aa) |