(24 nodes) Death Receptor Signaling network (Trypanosoma cruzi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4E649_TRYCC	Uncharacterized protein. (671 aa)
	Q4CKN0_TRYCC	Uncharacterized protein. (425 aa)
	Q4CMV5_TRYCC	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (372 aa)
	Q4CSA5_TRYCC	WD_REPEATS_REGION domain-containing protein. (438 aa)
	Q4CUF7_TRYCC	Mucin-associated surface protein (MASP), putative. (444 aa)
	Q4CX04_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (209 aa)
	Q4CXN0_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (211 aa)
	Q4CXZ1_TRYCC	WD_REPEATS_REGION domain-containing protein. (438 aa)
	Q4CZS8_TRYCC	Uncharacterized protein. (728 aa)
	Q4D1T6_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (150 aa)
	Q4D6K0_TRYCC	Ubiquitin-like protein, putative. (624 aa)
	Q4DEG8_TRYCC	Mucin-associated surface protein (MASP), putative. (603 aa)
	Q4DEM3_TRYCC	Uncharacterized protein. (728 aa)
	Q4DF61_TRYCC	Mucin-associated surface protein (MASP), putative. (532 aa)
	Q4DGS4_TRYCC	Ubiquitin-like protein, putative. (622 aa)
	Q4DH09_TRYCC	Mucin-associated surface protein (MASP), putative. (336 aa)
	Q4DSQ4_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (150 aa)
	Q4DT71_TRYCC	Uncharacterized protein. (440 aa)
	Q4DTN2_TRYCC	Activated protein kinase C receptor, putative. (318 aa)
	Q4DW77_TRYCC	Mucin-associated surface protein (MASP), putative. (364 aa)
	Q4DXI4_TRYCC	Uncharacterized protein. (440 aa)
	Q4E0Z2_TRYCC	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (372 aa)
	Q4E1I6_TRYCC	Mucin-associated surface protein (MASP), putative. (433 aa)
	Q4E3X8_TRYCC	Mucin-associated surface protein (MASP), putative. (325 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CMV5_TRYCC	Q4CZS8_TRYCC	Q4CMV5	Q4CZS8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.981
Q4CMV5_TRYCC	Q4DEM3_TRYCC	Q4CMV5	Q4DEM3	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.981
Q4CSA5_TRYCC	Q4CX04_TRYCC	Q4CSA5	Q4CX04	WD_REPEATS_REGION domain-containing protein.	Ubiquitin/ribosomal protein S27a, putative.	0.756
Q4CSA5_TRYCC	Q4CXN0_TRYCC	Q4CSA5	Q4CXN0	WD_REPEATS_REGION domain-containing protein.	Ubiquitin/ribosomal protein S27a, putative.	0.756
Q4CSA5_TRYCC	Q4D1T6_TRYCC	Q4CSA5	Q4D1T6	WD_REPEATS_REGION domain-containing protein.	Ubiquitin/ribosomal protein S27a, putative.	0.756
Q4CSA5_TRYCC	Q4D6K0_TRYCC	Q4CSA5	Q4D6K0	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like protein, putative.	0.756
Q4CSA5_TRYCC	Q4DGS4_TRYCC	Q4CSA5	Q4DGS4	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like protein, putative.	0.756
Q4CSA5_TRYCC	Q4DSQ4_TRYCC	Q4CSA5	Q4DSQ4	WD_REPEATS_REGION domain-containing protein.	Ubiquitin/ribosomal protein S27a, putative.	0.756
Q4CX04_TRYCC	Q4CSA5_TRYCC	Q4CX04	Q4CSA5	Ubiquitin/ribosomal protein S27a, putative.	WD_REPEATS_REGION domain-containing protein.	0.756
Q4CX04_TRYCC	Q4CXZ1_TRYCC	Q4CX04	Q4CXZ1	Ubiquitin/ribosomal protein S27a, putative.	WD_REPEATS_REGION domain-containing protein.	0.756
Q4CX04_TRYCC	Q4D1T6_TRYCC	Q4CX04	Q4D1T6	Ubiquitin/ribosomal protein S27a, putative.	Ubiquitin/ribosomal protein S27a, putative.	0.900
Q4CX04_TRYCC	Q4DSQ4_TRYCC	Q4CX04	Q4DSQ4	Ubiquitin/ribosomal protein S27a, putative.	Ubiquitin/ribosomal protein S27a, putative.	0.979
Q4CX04_TRYCC	Q4DT71_TRYCC	Q4CX04	Q4DT71	Ubiquitin/ribosomal protein S27a, putative.	Uncharacterized protein.	0.756
Q4CX04_TRYCC	Q4DTN2_TRYCC	Q4CX04	Q4DTN2	Ubiquitin/ribosomal protein S27a, putative.	Activated protein kinase C receptor, putative.	0.984
Q4CX04_TRYCC	Q4DXI4_TRYCC	Q4CX04	Q4DXI4	Ubiquitin/ribosomal protein S27a, putative.	Uncharacterized protein.	0.756
Q4CXN0_TRYCC	Q4CSA5_TRYCC	Q4CXN0	Q4CSA5	Ubiquitin/ribosomal protein S27a, putative.	WD_REPEATS_REGION domain-containing protein.	0.756
Q4CXN0_TRYCC	Q4CXZ1_TRYCC	Q4CXN0	Q4CXZ1	Ubiquitin/ribosomal protein S27a, putative.	WD_REPEATS_REGION domain-containing protein.	0.756
Q4CXN0_TRYCC	Q4DT71_TRYCC	Q4CXN0	Q4DT71	Ubiquitin/ribosomal protein S27a, putative.	Uncharacterized protein.	0.756
Q4CXN0_TRYCC	Q4DTN2_TRYCC	Q4CXN0	Q4DTN2	Ubiquitin/ribosomal protein S27a, putative.	Activated protein kinase C receptor, putative.	0.925
Q4CXN0_TRYCC	Q4DXI4_TRYCC	Q4CXN0	Q4DXI4	Ubiquitin/ribosomal protein S27a, putative.	Uncharacterized protein.	0.756