(76 nodes) Autophagy network (Trypanosoma cruzi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4D7S0_TRYCC	Uncharacterized protein. (675 aa)
	Q4D706_TRYCC	Ubiquitin activating E1 enzyme, putative. (762 aa)
	Q4D6R1_TRYCC	EF-hand domain-containing protein. (136 aa)
	Q4D6K0_TRYCC	Ubiquitin-like protein, putative. (624 aa)
	Q4D6D8_TRYCC	DJ-1_PfpI domain-containing protein. (198 aa)
	Q4D5K1_TRYCC	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (357 aa)
	Q4D586_TRYCC	DJ-1_PfpI domain-containing protein. (198 aa)
	Q4D4U9_TRYCC	EF-hand domain-containing protein. (136 aa)
	Q4D450_TRYCC	Uncharacterized protein. (227 aa)
	Q4D2Q9_TRYCC	Phosphatidylinositol kinase domain protein, putative; Belongs to the PI3/PI4-kinase family. (4095 aa)
	Q4D1T6_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (150 aa)
	Q4D0R2_TRYCC	Intraflagellar transport protein IFT88, putative. (213 aa)
	Q4D0M7_TRYCC	Uncharacterized protein. (219 aa)
	Q4D0B5_TRYCC	Uncharacterized protein. (249 aa)
	Q4D085_TRYCC	Uncharacterized protein. (500 aa)
	Q4CXN0_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (211 aa)
	Q4CX04_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (209 aa)
	Q4CWL8_TRYCC	Uncharacterized protein. (386 aa)
	Q4CW55_TRYCC	WD_REPEATS_REGION domain-containing protein. (1457 aa)
	Q4CW21_TRYCC	Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family. (392 aa)
	Q4CW12_TRYCC	Uncharacterized protein. (449 aa)
	Q4DPQ9_TRYCC	Peroxisome targeting signal 1 receptor, putative. (668 aa)
	Q4DNQ2_TRYCC	Uncharacterized protein. (227 aa)
	Q4DNI0_TRYCC	Small GTPase, putative. (355 aa)
	Q4DLI0_TRYCC	Phosphoglycerate mutase-like protein, putative. (281 aa)
	Q4DKY5_TRYCC	SNF7-like protein, putative. (218 aa)
	Q4DJR5_TRYCC	Phosphatidylinositol kinase domain protein, putative; Belongs to the PI3/PI4-kinase family. (4234 aa)
	Q4DHD6_TRYCC	WD_REPEATS_REGION domain-containing protein. (547 aa)
	Q4DGX9_TRYCC	Uncharacterized protein. (427 aa)
	Q4DGX5_TRYCC	Autophagy-related protein 3. (270 aa)
	Q4DGS4_TRYCC	Ubiquitin-like protein, putative. (622 aa)
	Q4DG40_TRYCC	Casein kinase II, putative; Belongs to the protein kinase superfamily. (345 aa)
	Q4DFC9_TRYCC	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (328 aa)
	Q4DET4_TRYCC	Uncharacterized protein. (446 aa)
	Q4DDQ7_TRYCC	Phosphoglycerate mutase-like protein, putative. (320 aa)
	Q4DBK8_TRYCC	Uncharacterized protein. (427 aa)
	Q4DBK4_TRYCC	Autophagy-related protein 3. (270 aa)
	Q4D9W3_TRYCC	APG6 domain-containing protein. (898 aa)
	Q4D9G7_TRYCC	Peroxisome targeting signal 1 receptor, putative. (674 aa)
	Q4D9F6_TRYCC	WD_REPEATS_REGION domain-containing protein. (1533 aa)
	Q4CL16_TRYCC	Phosphatidylinositol kinase domain protein, putative. (129 aa)
	Q4CLA1_TRYCC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	Q4CMF5_TRYCC	WD_REPEATS_REGION domain-containing protein. (1021 aa)
	Q4CMM8_TRYCC	Small GTPase, putative. (355 aa)
	Q4CN56_TRYCC	Uncharacterized protein. (197 aa)
	Q4CNV7_TRYCC	Intraflagellar transport protein IFT88, putative. (284 aa)
	Q4CQM1_TRYCC	SNF7-like protein, putative. (218 aa)
	Q4CQN8_TRYCC	Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family. (287 aa)
	Q4CSX2_TRYCC	Casein kinase II, alpha chain, putative; Belongs to the protein kinase superfamily. (408 aa)
	Q4CUT6_TRYCC	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (279 aa)
	Q4CV45_TRYCC	Uncharacterized protein. (1373 aa)
	Q4CV52_TRYCC	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (328 aa)
	Q4E4P6_TRYCC	Raptor_N domain-containing protein. (1297 aa)
	Q4E4K7_TRYCC	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (681 aa)
	Q4E3B1_TRYCC	Uncharacterized protein. (215 aa)
	Q4E340_TRYCC	Casein kinase II, alpha chain, putative; Belongs to the protein kinase superfamily. (405 aa)
	Q4E0D5_TRYCC	Raptor_N domain-containing protein. (367 aa)
	Q4DZR3_TRYCC	Ubiquitin activating E1 enzyme, putative. (762 aa)
	Q4DYN9_TRYCC	AMPKBI domain-containing protein. (311 aa)
	Q4DYH2_TRYCC	Ubiquitin-conjugating enzyme variant Kua homologue, putative. (270 aa)
	Q4DXC3_TRYCC	Protein kinase, putative. (1341 aa)
	Q4DWZ7_TRYCC	Autophagy-related protein. (289 aa)
	Q4DV83_TRYCC	Autophagy-related protein. (123 aa)
	Q4DV13_TRYCC	Uncharacterized protein. (248 aa)
	Q4DU79_TRYCC	Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family. (907 aa)
	Q4DSR9_TRYCC	APG6 domain-containing protein. (898 aa)
	Q4DSQ4_TRYCC	Ubiquitin/ribosomal protein S27a, putative. (150 aa)
	Q4DRI6_TRYCC	Uncharacterized protein. (219 aa)
	Q4DRG9_TRYCC	WD_REPEATS_REGION domain-containing protein. (547 aa)
	Q4DRE5_TRYCC	Uncharacterized protein. (449 aa)
	Q4DQY0_TRYCC	AMPKBI domain-containing protein. (310 aa)
	Q4DQT1_TRYCC	Autophagy-related protein. (326 aa)
	Q4DQN8_TRYCC	Raptor_N domain-containing protein. (1755 aa)
	Q4DQI1_TRYCC	WD_REPEATS_REGION domain-containing protein. (1533 aa)
	Q4DQE3_TRYCC	Intraflagellar transport protein IFT88, putative. (173 aa)
	Q4DP12_TRYCC	Uncharacterized protein. (446 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CL16_TRYCC	Q4D9G7_TRYCC	Q4CL16	Q4D9G7	Phosphatidylinositol kinase domain protein, putative.	Peroxisome targeting signal 1 receptor, putative.	0.687
Q4CL16_TRYCC	Q4DPQ9_TRYCC	Q4CL16	Q4DPQ9	Phosphatidylinositol kinase domain protein, putative.	Peroxisome targeting signal 1 receptor, putative.	0.687
Q4CL16_TRYCC	Q4DQT1_TRYCC	Q4CL16	Q4DQT1	Phosphatidylinositol kinase domain protein, putative.	Autophagy-related protein.	0.482
Q4CL16_TRYCC	Q4DV83_TRYCC	Q4CL16	Q4DV83	Phosphatidylinositol kinase domain protein, putative.	Autophagy-related protein.	0.482
Q4CL16_TRYCC	Q4DWZ7_TRYCC	Q4CL16	Q4DWZ7	Phosphatidylinositol kinase domain protein, putative.	Autophagy-related protein.	0.482
Q4CLA1_TRYCC	Q4CN56_TRYCC	Q4CLA1	Q4CN56	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.489
Q4CLA1_TRYCC	Q4CSX2_TRYCC	Q4CLA1	Q4CSX2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Casein kinase II, alpha chain, putative; Belongs to the protein kinase superfamily.	0.442
Q4CLA1_TRYCC	Q4D085_TRYCC	Q4CLA1	Q4D085	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.489
Q4CLA1_TRYCC	Q4D450_TRYCC	Q4CLA1	Q4D450	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.784
Q4CLA1_TRYCC	Q4DG40_TRYCC	Q4CLA1	Q4DG40	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Casein kinase II, putative; Belongs to the protein kinase superfamily.	0.442
Q4CLA1_TRYCC	Q4DNQ2_TRYCC	Q4CLA1	Q4DNQ2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.784
Q4CLA1_TRYCC	Q4E340_TRYCC	Q4CLA1	Q4E340	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Casein kinase II, alpha chain, putative; Belongs to the protein kinase superfamily.	0.442
Q4CMF5_TRYCC	Q4CQN8_TRYCC	Q4CMF5	Q4CQN8	WD_REPEATS_REGION domain-containing protein.	Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family.	0.624
Q4CMF5_TRYCC	Q4CW21_TRYCC	Q4CMF5	Q4CW21	WD_REPEATS_REGION domain-containing protein.	Phosphatidylinositol 3-kinase, putative; Belongs to the PI3/PI4-kinase family.	0.624
Q4CMF5_TRYCC	Q4D706_TRYCC	Q4CMF5	Q4D706	WD_REPEATS_REGION domain-containing protein.	Ubiquitin activating E1 enzyme, putative.	0.655
Q4CMF5_TRYCC	Q4D9W3_TRYCC	Q4CMF5	Q4D9W3	WD_REPEATS_REGION domain-containing protein.	APG6 domain-containing protein.	0.715
Q4CMF5_TRYCC	Q4DBK4_TRYCC	Q4CMF5	Q4DBK4	WD_REPEATS_REGION domain-containing protein.	Autophagy-related protein 3.	0.847
Q4CMF5_TRYCC	Q4DGX5_TRYCC	Q4CMF5	Q4DGX5	WD_REPEATS_REGION domain-containing protein.	Autophagy-related protein 3.	0.847
Q4CMF5_TRYCC	Q4DP12_TRYCC	Q4CMF5	Q4DP12	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.969
Q4CMF5_TRYCC	Q4DQT1_TRYCC	Q4CMF5	Q4DQT1	WD_REPEATS_REGION domain-containing protein.	Autophagy-related protein.	0.648