STRINGSTRING
Q4E5P5_TRYCC Q4E5P5_TRYCC CYP51 CYP51 Q4CPP0_TRYCC Q4CPP0_TRYCC Q4CNG3_TRYCC Q4CNG3_TRYCC Q4CN65_TRYCC Q4CN65_TRYCC Q4CN58_TRYCC Q4CN58_TRYCC Q4CMU6_TRYCC Q4CMU6_TRYCC Q4CMH3_TRYCC Q4CMH3_TRYCC Q4CMF1_TRYCC Q4CMF1_TRYCC Q4CLA9_TRYCC Q4CLA9_TRYCC Q4CKK4_TRYCC Q4CKK4_TRYCC Q4E2R7_TRYCC Q4E2R7_TRYCC ALP3 ALP3 Q4D0N7_TRYCC Q4D0N7_TRYCC Q4D192_TRYCC Q4D192_TRYCC Q4D193_TRYCC Q4D193_TRYCC ALP1 ALP1 Q4D3A5_TRYCC Q4D3A5_TRYCC Q4D3A7_TRYCC Q4D3A7_TRYCC Q4D3P5_TRYCC Q4D3P5_TRYCC Q4D5C2_TRYCC Q4D5C2_TRYCC Q4D5P4_TRYCC Q4D5P4_TRYCC Q4D634_TRYCC Q4D634_TRYCC Q4D729_TRYCC Q4D729_TRYCC Q4D7Y4_TRYCC Q4D7Y4_TRYCC Q4DDL6_TRYCC Q4DDL6_TRYCC Q4DDX3_TRYCC Q4DDX3_TRYCC Q4DEL1_TRYCC Q4DEL1_TRYCC Q4DFA6_TRYCC Q4DFA6_TRYCC Q4DGP8_TRYCC Q4DGP8_TRYCC Q4DHV6_TRYCC Q4DHV6_TRYCC Q4DIF6_TRYCC Q4DIF6_TRYCC Q4DNV7_TRYCC Q4DNV7_TRYCC Q4DNV8_TRYCC Q4DNV8_TRYCC Q4DP98_TRYCC Q4DP98_TRYCC Q4DQ27_TRYCC Q4DQ27_TRYCC Q4DQI9_TRYCC Q4DQI9_TRYCC Q4DQP2_TRYCC Q4DQP2_TRYCC Q4DRI4_TRYCC Q4DRI4_TRYCC Q4DRI5_TRYCC Q4DRI5_TRYCC Q4DSJ2_TRYCC Q4DSJ2_TRYCC Q4DV71_TRYCC Q4DV71_TRYCC Q4DW03_TRYCC Q4DW03_TRYCC Q4DWV8_TRYCC Q4DWV8_TRYCC Q4DX96_TRYCC Q4DX96_TRYCC Q4DY23_TRYCC Q4DY23_TRYCC Q4DZE6_TRYCC Q4DZE6_TRYCC Q4E0J7_TRYCC Q4E0J7_TRYCC Q4E0Q0_TRYCC Q4E0Q0_TRYCC Q4E156_TRYCC Q4E156_TRYCC Q4E2P2_TRYCC Q4E2P2_TRYCC Q4D080_TRYCC Q4D080_TRYCC Q4E2S6_TRYCC Q4E2S6_TRYCC Q4E2Y7_TRYCC Q4E2Y7_TRYCC Q4E3F7_TRYCC Q4E3F7_TRYCC Q4E3P5_TRYCC Q4E3P5_TRYCC Q4E3S6_TRYCC Q4E3S6_TRYCC Q4E5I4_TRYCC Q4E5I4_TRYCC Q4E5I9_TRYCC Q4E5I9_TRYCC Q4E5M4_TRYCC Q4E5M4_TRYCC Q4CPZ0_TRYCC Q4CPZ0_TRYCC Q4CR18_TRYCC Q4CR18_TRYCC Q4CRK6_TRYCC Q4CRK6_TRYCC Q4CS04_TRYCC Q4CS04_TRYCC Q4CS05_TRYCC Q4CS05_TRYCC Q4CTW9_TRYCC Q4CTW9_TRYCC Q4CTX0_TRYCC Q4CTX0_TRYCC Q4CTX1_TRYCC Q4CTX1_TRYCC Q4CTX2_TRYCC Q4CTX2_TRYCC Q4CTX9_TRYCC Q4CTX9_TRYCC Q4CTY0_TRYCC Q4CTY0_TRYCC Q4CV00_TRYCC Q4CV00_TRYCC Q4CVH4_TRYCC Q4CVH4_TRYCC Q4CVJ5_TRYCC Q4CVJ5_TRYCC Q4CXR1_TRYCC Q4CXR1_TRYCC Q4CYQ7_TRYCC Q4CYQ7_TRYCC Q4CYQ8_TRYCC Q4CYQ8_TRYCC Q4D004_TRYCC Q4D004_TRYCC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q4E5P5_TRYCCCytochrome C oxidase subunit IV, putative. (334 aa)
CYP51Sterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). Favors C4 dimethylated substrates, the substrate preference order is 24- methylenedihydrolanosterol > 24,25-dihydrolanosterol > lanosterol > obtusifoliol > norlanosterol; Belongs to the cytochrome P450 family. (481 aa)
Q4CPP0_TRYCCCo-chaperone GrpE, putative; Belongs to the GrpE family. (219 aa)
Q4CNG3_TRYCCCo-chaperone GrpE, putative; Belongs to the GrpE family. (219 aa)
Q4CN65_TRYCCPhosphoglycerate kinase, putative. (201 aa)
Q4CN58_TRYCCActin, putative. (154 aa)
Q4CMU6_TRYCCCysteine peptidase, putative; Belongs to the peptidase C1 family. (467 aa)
Q4CMH3_TRYCCProtein disulfide isomerase, putative. (163 aa)
Q4CMF1_TRYCCHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
Q4CLA9_TRYCCActin, putative; Belongs to the actin family. (288 aa)
Q4CKK4_TRYCCActin, putative. (178 aa)
Q4E2R7_TRYCCCarboxypeptidase, putative. (503 aa)
ALP3Actin-like protein 3; Belongs to the actin family. (426 aa)
Q4D0N7_TRYCC69 kDa paraflagellar rod protein, putative. (359 aa)
Q4D192_TRYCCPhosphoglycerate kinase. (588 aa)
Q4D193_TRYCCPhosphoglycerate kinase. (419 aa)
ALP1Actin-like protein 1; Belongs to the actin family. (390 aa)
Q4D3A5_TRYCCKinetoplastid membrane protein KMP-11. (76 aa)
Q4D3A7_TRYCCKinetoplastid membrane protein KMP-11, putative. (91 aa)
Q4D3P5_TRYCCPhosphotransferase. (471 aa)
Q4D5C2_TRYCCGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
Q4D5P4_TRYCC40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (273 aa)
Q4D634_TRYCCParaflagellar rod protein 3, putative. (589 aa)
Q4D729_TRYCCHslvu complex proteolytic subunit-like, putative. (209 aa)
Q4D7Y4_TRYCCKinetoplastid membrane protein KMP-11, putative. (92 aa)
Q4DDL6_TRYCCHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
Q4DDX3_TRYCCCalreticulin. (401 aa)
Q4DEL1_TRYCCHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
Q4DFA6_TRYCCProtein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (376 aa)
Q4DGP8_TRYCCPhosphoglycerate kinase. (527 aa)
Q4DHV6_TRYCCAminotransferase, putative. (437 aa)
Q4DIF6_TRYCC69 kDa paraflagellar rod protein, putative. (600 aa)
Q4DNV7_TRYCCPhosphoglycerate kinase. (503 aa)
Q4DNV8_TRYCCPhosphoglycerate kinase. (419 aa)
Q4DP98_TRYCCPhosphoglycerate kinase, putative. (115 aa)
Q4DQ27_TRYCCPhosphotransferase. (471 aa)
Q4DQI9_TRYCCProtein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (181 aa)
Q4DQP2_TRYCCTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
Q4DRI4_TRYCCFlagellar calcium-binding protein, putative. (181 aa)
Q4DRI5_TRYCCFlagellar calcium-binding protein, putative. (211 aa)
Q4DSJ2_TRYCCCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1103 aa)
Q4DV71_TRYCCProtein disulfide isomerase, putative. (141 aa)
Q4DW03_TRYCCCysteine peptidase, putative; Belongs to the peptidase C1 family. (467 aa)
Q4DWV8_TRYCCGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
Q4DX96_TRYCCPhosphoglycerate kinase. (527 aa)
Q4DY23_TRYCCAlcohol dehydrogenase, putative. (392 aa)
Q4DZE6_TRYCCLanosterol synthase, putative; Belongs to the terpene cyclase/mutase family. (902 aa)
Q4E0J7_TRYCCCysteine peptidase, putative; Belongs to the peptidase C1 family. (467 aa)
Q4E0Q0_TRYCCPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (913 aa)
Q4E156_TRYCCProtein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (209 aa)
Q4E2P2_TRYCCCytochrome C oxidase subunit IV, putative. (334 aa)
Q4D080_TRYCCAspartate aminotransferase. (404 aa)
Q4E2S6_TRYCCPhosphoglycerate kinase. (906 aa)
Q4E2Y7_TRYCCLanosterol synthase, putative; Belongs to the terpene cyclase/mutase family. (902 aa)
Q4E3F7_TRYCCProtein disulfide-isomerase. (481 aa)
Q4E3P5_TRYCCPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (913 aa)
Q4E3S6_TRYCCCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1101 aa)
Q4E5I4_TRYCCCitrate synthase; Belongs to the citrate synthase family. (472 aa)
Q4E5I9_TRYCCAlcohol dehydrogenase, putative. (392 aa)
Q4E5M4_TRYCCCysteine peptidase, putative; Belongs to the peptidase C1 family. (322 aa)
Q4CPZ0_TRYCCCalreticulin. (401 aa)
Q4CR18_TRYCCGlutamate dehydrogenase, putative. (383 aa)
Q4CRK6_TRYCCAspartate aminotransferase. (404 aa)
Q4CS04_TRYCCFlagellar calcium-binding protein, putative. (108 aa)
Q4CS05_TRYCCFlagellar calcium-binding protein, putative. (211 aa)
Q4CTW9_TRYCCFlagellar calcium-binding protein, putative. (79 aa)
Q4CTX0_TRYCCFlagellar calcium-binding protein, putative. (211 aa)
Q4CTX1_TRYCCFlagellar calcium-binding protein, putative. (211 aa)
Q4CTX2_TRYCCFlagellar calcium-binding protein, putative. (211 aa)
Q4CTX9_TRYCCCysteine peptidase, putative. (181 aa)
Q4CTY0_TRYCCCysteine peptidase, putative. (175 aa)
Q4CV00_TRYCCCysteine peptidase, putative; Belongs to the peptidase C1 family. (426 aa)
Q4CVH4_TRYCCGlutamate dehydrogenase, putative. (211 aa)
Q4CVJ5_TRYCCCitrate synthase; Belongs to the citrate synthase family. (472 aa)
Q4CXR1_TRYCCHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (62 aa)
Q4CYQ7_TRYCCActin, putative. (114 aa)
Q4CYQ8_TRYCCActin, putative. (376 aa)
Q4D004_TRYCCProtein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (263 aa)
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.