37 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4DHP0_TRYCC	Phosphatase 2C, putative. (382 aa)
	Q4DHF8_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (387 aa)
	Q4DG65_TRYCC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa)
	Q4DFG3_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (554 aa)
	Q4DFA6_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (376 aa)
	Q4DDX3_TRYCC	Calreticulin. (401 aa)
	Q4DCP7_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (342 aa)
	Q4D6R4_TRYCC	Aldehyde dehydrogenase, putative. (219 aa)
	Q4D620_TRYCC	Glucose-regulated protein 78, putative; Belongs to the heat shock protein 70 family. (651 aa)
	Q4D4U6_TRYCC	Aldehyde dehydrogenase, putative. (194 aa)
	Q4D301_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4D2Z9_TRYCC	Tryparedoxin peroxidase. (199 aa)
	Q4D004_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (263 aa)
	Q4CZ29_TRYCC	Thiol-dependent reductase 1, putative; Belongs to the GST superfamily. (445 aa)
	Q4CY92_TRYCC	Tryparedoxin peroxidase, putative. (113 aa)
	Q4CX87_TRYCC	Tryparedoxin peroxidase, putative. (226 aa)
	Q4CVR5_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CU94_TRYCC	Mannose-1-phosphate guanyltransferase, putative. (383 aa)
	Q4CSC4_TRYCC	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (394 aa)
	Q4CQS1_TRYCC	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (263 aa)
	Q4CQA8_TRYCC	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (263 aa)
	Q4CPZ0_TRYCC	Calreticulin. (401 aa)
	Q4CMK4_TRYCC	Mannose-1-phosphate guanyltransferase, putative. (383 aa)
	Q4CMH3_TRYCC	Protein disulfide isomerase, putative. (163 aa)
	Q4CM56_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CLA1_TRYCC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	Q4DZ74_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	Q4E0F6_TRYCC	Eukaryotic initiation factor 4a, putative; Belongs to the DEAD box helicase family. (438 aa)
	Q4E156_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (209 aa)
	IF4A_TRYCC	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (404 aa)
	Q4E3F7_TRYCC	Protein disulfide-isomerase. (481 aa)
	Q4E4L7_TRYCC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
	Q4DYS1_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (504 aa)
	Q4DVV3_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	Q4DV71_TRYCC	Protein disulfide isomerase, putative. (141 aa)
	Q4DQI9_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (181 aa)
	Q4DKI7_TRYCC	Thiol-dependent reductase 1, putative; Belongs to the GST superfamily. (445 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IF4A_TRYCC	Q4E0F6_TRYCC	Q4E162	Q4E0F6	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic initiation factor 4a, putative; Belongs to the DEAD box helicase family.	0.900
Q4CLA1_TRYCC	Q4CMH3_TRYCC	Q4CLA1	Q4CMH3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative.	0.523
Q4CLA1_TRYCC	Q4CSC4_TRYCC	Q4CLA1	Q4CSC4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.493
Q4CLA1_TRYCC	Q4D004_TRYCC	Q4CLA1	Q4D004	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.407
Q4CLA1_TRYCC	Q4D620_TRYCC	Q4CLA1	Q4D620	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Glucose-regulated protein 78, putative; Belongs to the heat shock protein 70 family.	0.898
Q4CLA1_TRYCC	Q4DFA6_TRYCC	Q4CLA1	Q4DFA6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.407
Q4CLA1_TRYCC	Q4DQI9_TRYCC	Q4CLA1	Q4DQI9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.523
Q4CLA1_TRYCC	Q4DV71_TRYCC	Q4CLA1	Q4DV71	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative.	0.407
Q4CLA1_TRYCC	Q4DYS1_TRYCC	Q4CLA1	Q4DYS1	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family.	0.490
Q4CLA1_TRYCC	Q4E156_TRYCC	Q4CLA1	Q4E156	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.523
Q4CLA1_TRYCC	Q4E3F7_TRYCC	Q4CLA1	Q4E3F7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein disulfide-isomerase.	0.523
Q4CM56_TRYCC	Q4CMH3_TRYCC	Q4CM56	Q4CMH3	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative.	0.665
Q4CM56_TRYCC	Q4CSC4_TRYCC	Q4CM56	Q4CSC4	Tryparedoxin peroxidase, putative.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.525
Q4CM56_TRYCC	Q4D004_TRYCC	Q4CM56	Q4D004	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.665
Q4CM56_TRYCC	Q4DFA6_TRYCC	Q4CM56	Q4DFA6	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.665
Q4CM56_TRYCC	Q4DQI9_TRYCC	Q4CM56	Q4DQI9	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.665
Q4CM56_TRYCC	Q4DV71_TRYCC	Q4CM56	Q4DV71	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative.	0.665
Q4CM56_TRYCC	Q4E156_TRYCC	Q4CM56	Q4E156	Tryparedoxin peroxidase, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.665
Q4CM56_TRYCC	Q4E3F7_TRYCC	Q4CM56	Q4E3F7	Tryparedoxin peroxidase, putative.	Protein disulfide-isomerase.	0.666
Q4CMH3_TRYCC	Q4CLA1_TRYCC	Q4CMH3	Q4CLA1	Protein disulfide isomerase, putative.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.523