20 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4CY92_TRYCC	Tryparedoxin peroxidase, putative. (113 aa)
	Q4D2Z9_TRYCC	Tryparedoxin peroxidase. (199 aa)
	Q4D1B8_TRYCC	Tryparedoxin, putative. (144 aa)
	Q4D080_TRYCC	Aspartate aminotransferase. (404 aa)
	Q4E5N8_TRYCC	Alanine aminotransferase, putative. (497 aa)
	Q4E2N8_TRYCC	Alanine aminotransferase, putative. (493 aa)
	Q4E2N6_TRYCC	Alanine aminotransferase, putative. (497 aa)
	Q4DL41_TRYCC	Reductase, putative. (325 aa)
	Q4D301_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4D1B9_TRYCC	Tryparedoxin, putative. (193 aa)
	Q4CX87_TRYCC	Tryparedoxin peroxidase, putative. (226 aa)
	Q4CVR5_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CT43_TRYCC	Trypanothione reductase, putative. (492 aa)
	Q4CRK6_TRYCC	Aspartate aminotransferase. (404 aa)
	Q4CMQ7_TRYCC	Trypanothione reductase, putative. (388 aa)
	Q4CML2_TRYCC	Glucose-6-phosphate dehydrogenase, putative. (279 aa)
	Q4CM56_TRYCC	Tryparedoxin peroxidase, putative. (199 aa)
	Q4CL55_TRYCC	Trypanothione reductase, putative. (189 aa)
	Q4E5P0_TRYCC	Alanine aminotransferase, putative. (493 aa)
	TRS	Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family. (647 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CL55_TRYCC	Q4CM56_TRYCC	Q4CL55	Q4CM56	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CML2_TRYCC	Q4CL55	Q4CML2	Trypanothione reductase, putative.	Glucose-6-phosphate dehydrogenase, putative.	0.667
Q4CL55_TRYCC	Q4CRK6_TRYCC	Q4CL55	Q4CRK6	Trypanothione reductase, putative.	Aspartate aminotransferase.	0.415
Q4CL55_TRYCC	Q4CVR5_TRYCC	Q4CL55	Q4CVR5	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CX87_TRYCC	Q4CL55	Q4CX87	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4CY92_TRYCC	Q4CL55	Q4CY92	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4D080_TRYCC	Q4CL55	Q4D080	Trypanothione reductase, putative.	Aspartate aminotransferase.	0.415
Q4CL55_TRYCC	Q4D1B8_TRYCC	Q4CL55	Q4D1B8	Trypanothione reductase, putative.	Tryparedoxin, putative.	0.805
Q4CL55_TRYCC	Q4D1B9_TRYCC	Q4CL55	Q4D1B9	Trypanothione reductase, putative.	Tryparedoxin, putative.	0.805
Q4CL55_TRYCC	Q4D2Z9_TRYCC	Q4CL55	Q4D2Z9	Trypanothione reductase, putative.	Tryparedoxin peroxidase.	0.885
Q4CL55_TRYCC	Q4D301_TRYCC	Q4CL55	Q4D301	Trypanothione reductase, putative.	Tryparedoxin peroxidase, putative.	0.885
Q4CL55_TRYCC	Q4DL41_TRYCC	Q4CL55	Q4DL41	Trypanothione reductase, putative.	Reductase, putative.	0.614
Q4CL55_TRYCC	TRS	Q4CL55	Q9GT49	Trypanothione reductase, putative.	Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.	0.642
Q4CM56_TRYCC	Q4CL55_TRYCC	Q4CM56	Q4CL55	Tryparedoxin peroxidase, putative.	Trypanothione reductase, putative.	0.885
Q4CM56_TRYCC	Q4CMQ7_TRYCC	Q4CM56	Q4CMQ7	Tryparedoxin peroxidase, putative.	Trypanothione reductase, putative.	0.885
Q4CM56_TRYCC	Q4CT43_TRYCC	Q4CM56	Q4CT43	Tryparedoxin peroxidase, putative.	Trypanothione reductase, putative.	0.885
Q4CM56_TRYCC	Q4D1B8_TRYCC	Q4CM56	Q4D1B8	Tryparedoxin peroxidase, putative.	Tryparedoxin, putative.	0.804
Q4CM56_TRYCC	Q4D1B9_TRYCC	Q4CM56	Q4D1B9	Tryparedoxin peroxidase, putative.	Tryparedoxin, putative.	0.804
Q4CM56_TRYCC	TRS	Q4CM56	Q9GT49	Tryparedoxin peroxidase, putative.	Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.	0.960
Q4CML2_TRYCC	Q4CL55_TRYCC	Q4CML2	Q4CL55	Glucose-6-phosphate dehydrogenase, putative.	Trypanothione reductase, putative.	0.667