28 items (Trypanosoma cruzi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q4CRB1_TRYCC	Major vault protein, putative. (610 aa)
	Q4DFA6_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (376 aa)
	Q4DFG3_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (554 aa)
	Q4DHF8_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (387 aa)
	Q4DL41_TRYCC	Reductase, putative. (325 aa)
	Q4DQI9_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (181 aa)
	Q4DQP2_TRYCC	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	Q4DTM3_TRYCC	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (680 aa)
	Q4DV71_TRYCC	Protein disulfide isomerase, putative. (141 aa)
	Q4DVV3_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	Q4DY79_TRYCC	Short chain dehydrogenase/reductase, putative. (413 aa)
	Q4DY80_TRYCC	Short chain dehydrogenase/reductase, putative. (485 aa)
	Q4DYS1_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (504 aa)
	Q4DZ74_TRYCC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	Q4E156_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (209 aa)
	Q4E3F7_TRYCC	Protein disulfide-isomerase. (481 aa)
	Q4D118_TRYCC	Heat shock protein 70, putative. (249 aa)
	Q4CMH3_TRYCC	Protein disulfide isomerase, putative. (163 aa)
	Q4CUA0_TRYCC	Heat shock protein 70, putative. (291 aa)
	MVP_TRYCC	Major vault protein; Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport (By similarity). (838 aa)
	Q4CYD6_TRYCC	Major vault protein, putative. (214 aa)
	Q4D004_TRYCC	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (263 aa)
	Q4D4U6_TRYCC	Aldehyde dehydrogenase, putative. (194 aa)
	Q4D6R4_TRYCC	Aldehyde dehydrogenase, putative. (219 aa)
	Q4D6Y4_TRYCC	Heat shock protein 70, putative. (70 aa)
	Q4DA05_TRYCC	Short chain dehydrogenase/reductase, putative. (594 aa)
	Q4DA06_TRYCC	Short chain dehydrogenase/reductase, putative. (485 aa)
	Q4DCP7_TRYCC	Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (342 aa)

Your Current Organism:

Trypanosoma cruzi

NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q4CMH3_TRYCC	Q4CUA0_TRYCC	Q4CMH3	Q4CUA0	Protein disulfide isomerase, putative.	Heat shock protein 70, putative.	0.872
Q4CMH3_TRYCC	Q4DQP2_TRYCC	Q4CMH3	Q4DQP2	Protein disulfide isomerase, putative.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.545
Q4CRB1_TRYCC	Q4CYD6_TRYCC	Q4CRB1	Q4CYD6	Major vault protein, putative.	Major vault protein, putative.	0.589
Q4CUA0_TRYCC	Q4CMH3_TRYCC	Q4CUA0	Q4CMH3	Heat shock protein 70, putative.	Protein disulfide isomerase, putative.	0.872
Q4CUA0_TRYCC	Q4D004_TRYCC	Q4CUA0	Q4D004	Heat shock protein 70, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.604
Q4CUA0_TRYCC	Q4D118_TRYCC	Q4CUA0	Q4D118	Heat shock protein 70, putative.	Heat shock protein 70, putative.	0.827
Q4CUA0_TRYCC	Q4D6Y4_TRYCC	Q4CUA0	Q4D6Y4	Heat shock protein 70, putative.	Heat shock protein 70, putative.	0.648
Q4CUA0_TRYCC	Q4DFA6_TRYCC	Q4CUA0	Q4DFA6	Heat shock protein 70, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.604
Q4CUA0_TRYCC	Q4DQI9_TRYCC	Q4CUA0	Q4DQI9	Heat shock protein 70, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.872
Q4CUA0_TRYCC	Q4DQP2_TRYCC	Q4CUA0	Q4DQP2	Heat shock protein 70, putative.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.796
Q4CUA0_TRYCC	Q4DTM3_TRYCC	Q4CUA0	Q4DTM3	Heat shock protein 70, putative.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.650
Q4CUA0_TRYCC	Q4DV71_TRYCC	Q4CUA0	Q4DV71	Heat shock protein 70, putative.	Protein disulfide isomerase, putative.	0.604
Q4CUA0_TRYCC	Q4E156_TRYCC	Q4CUA0	Q4E156	Heat shock protein 70, putative.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.872
Q4CUA0_TRYCC	Q4E3F7_TRYCC	Q4CUA0	Q4E3F7	Heat shock protein 70, putative.	Protein disulfide-isomerase.	0.872
Q4CYD6_TRYCC	Q4CRB1_TRYCC	Q4CYD6	Q4CRB1	Major vault protein, putative.	Major vault protein, putative.	0.589
Q4D004_TRYCC	Q4CUA0_TRYCC	Q4D004	Q4CUA0	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	Heat shock protein 70, putative.	0.604
Q4D004_TRYCC	Q4DQI9_TRYCC	Q4D004	Q4DQI9	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.438
Q4D004_TRYCC	Q4E3F7_TRYCC	Q4D004	Q4E3F7	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase.	0.447
Q4D118_TRYCC	Q4CUA0_TRYCC	Q4D118	Q4CUA0	Heat shock protein 70, putative.	Heat shock protein 70, putative.	0.827
Q4D118_TRYCC	Q4DQP2_TRYCC	Q4D118	Q4DQP2	Heat shock protein 70, putative.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.721