STRINGSTRING
Q4CLL4_TRYCC Q4CLL4_TRYCC Q4CQR0_TRYCC Q4CQR0_TRYCC Q4CR40_TRYCC Q4CR40_TRYCC Q4CR96_TRYCC Q4CR96_TRYCC Q4CRT0_TRYCC Q4CRT0_TRYCC Q4CUG6_TRYCC Q4CUG6_TRYCC Q4CVK9_TRYCC Q4CVK9_TRYCC PURA2_TRYCC PURA2_TRYCC Q4CXJ7_TRYCC Q4CXJ7_TRYCC Q4CYT2_TRYCC Q4CYT2_TRYCC Q4CZI8_TRYCC Q4CZI8_TRYCC Q4D397_TRYCC Q4D397_TRYCC Q4D4A3_TRYCC Q4D4A3_TRYCC Q4D6V2_TRYCC Q4D6V2_TRYCC Q4D6Z4_TRYCC Q4D6Z4_TRYCC Q4D711_TRYCC Q4D711_TRYCC Q4D818_TRYCC Q4D818_TRYCC Q4D879_TRYCC Q4D879_TRYCC Q4D9I0_TRYCC Q4D9I0_TRYCC Q4D9Z4_TRYCC Q4D9Z4_TRYCC Q4DAJ9_TRYCC Q4DAJ9_TRYCC Q4DBH5_TRYCC Q4DBH5_TRYCC ITPA1_TRYCC ITPA1_TRYCC Q4DCB6_TRYCC Q4DCB6_TRYCC Q4DCU1_TRYCC Q4DCU1_TRYCC Q4DEE6_TRYCC Q4DEE6_TRYCC GMPR GMPR Q4DFS6_TRYCC Q4DFS6_TRYCC Q4DGA3_TRYCC Q4DGA3_TRYCC Q4DIR4_TRYCC Q4DIR4_TRYCC Q4DJ30_TRYCC Q4DJ30_TRYCC Q4DKC9_TRYCC Q4DKC9_TRYCC Q4DLI9_TRYCC Q4DLI9_TRYCC PURA1_TRYCC PURA1_TRYCC Q4DLV1_TRYCC Q4DLV1_TRYCC Q4DM24_TRYCC Q4DM24_TRYCC Q4DM82_TRYCC Q4DM82_TRYCC Q4DNZ4_TRYCC Q4DNZ4_TRYCC Q4DPB1_TRYCC Q4DPB1_TRYCC Q4DQV0_TRYCC Q4DQV0_TRYCC Q4DRC4_TRYCC Q4DRC4_TRYCC ITPA2_TRYCC ITPA2_TRYCC Q4DSS9_TRYCC Q4DSS9_TRYCC Q4DUS4_TRYCC Q4DUS4_TRYCC Q4DVM8_TRYCC Q4DVM8_TRYCC Q4DWB4_TRYCC Q4DWB4_TRYCC Q4DXL6_TRYCC Q4DXL6_TRYCC Q4DXL7_TRYCC Q4DXL7_TRYCC Q4DXW9_TRYCC Q4DXW9_TRYCC Q4DYD7_TRYCC Q4DYD7_TRYCC Q4DZ57_TRYCC Q4DZ57_TRYCC Q4E006_TRYCC Q4E006_TRYCC Q4E0S4_TRYCC Q4E0S4_TRYCC Q4E0Y5_TRYCC Q4E0Y5_TRYCC Q4E0Y6_TRYCC Q4E0Y6_TRYCC Q4E1D4_TRYCC Q4E1D4_TRYCC GMPR-2 GMPR-2 Q4E1S6_TRYCC Q4E1S6_TRYCC Q4E1U3_TRYCC Q4E1U3_TRYCC Q4E256_TRYCC Q4E256_TRYCC Q4E4D6_TRYCC Q4E4D6_TRYCC Q4E4G2_TRYCC Q4E4G2_TRYCC Q4E4R9_TRYCC Q4E4R9_TRYCC Q4E627_TRYCC Q4E627_TRYCC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q4CLL4_TRYCCAMP deaminase, putative. (249 aa)
Q4CQR0_TRYCCPhosphodiesterase. (929 aa)
Q4CR40_TRYCCSerine/threonine protein kinase, putative. (250 aa)
Q4CR96_TRYCCRibonucleoside-diphosphate reductase large chain, putative. (236 aa)
Q4CRT0_TRYCCInosine-adenosine-guanosine-nucleoside hydrolase, putative. (326 aa)
Q4CUG6_TRYCCInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (512 aa)
Q4CVK9_TRYCCAdenosine kinase, putative. (346 aa)
PURA2_TRYCCAdenylosuccinate synthetase 2; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). (616 aa)
Q4CXJ7_TRYCCAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (462 aa)
Q4CYT2_TRYCCAdenosine kinase, putative. (359 aa)
Q4CZI8_TRYCCPhosphoribosylpyrophosphate synthetase, putative. (184 aa)
Q4D397_TRYCCPhosphodiesterase. (924 aa)
Q4D4A3_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (218 aa)
Q4D6V2_TRYCCRibonucleoside-diphosphate reductase small chain, putative. (337 aa)
Q4D6Z4_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (260 aa)
Q4D711_TRYCCGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (452 aa)
Q4D818_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (198 aa)
Q4D879_TRYCCAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (181 aa)
Q4D9I0_TRYCCPhosphoribosylpyrophosphate synthetase, putative. (390 aa)
Q4D9Z4_TRYCCPyruvate kinase; Belongs to the pyruvate kinase family. (499 aa)
Q4DAJ9_TRYCCAMP deaminase, putative. (901 aa)
Q4DBH5_TRYCCAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (462 aa)
ITPA1_TRYCCInosine triphosphate pyrophosphatase 1; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
Q4DCB6_TRYCCRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (796 aa)
Q4DCU1_TRYCCPhosphoribosylpyrophosphate synthetase, putative. (390 aa)
Q4DEE6_TRYCCPhosphomannomutase-like protein, putative; Belongs to the phosphohexose mutase family. (585 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (491 aa)
Q4DFS6_TRYCCRibonucleoside-diphosphate reductase small chain, putative. (337 aa)
Q4DGA3_TRYCCHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (221 aa)
Q4DIR4_TRYCCRibose-phosphate pyrophosphokinase, putative. (705 aa)
Q4DJ30_TRYCCAcidocalcisomal exopolyphosphatase, putative. (383 aa)
Q4DKC9_TRYCCReceptor-type adenylate cyclase, putative. (1281 aa)
Q4DLI9_TRYCCPhosphoglucomutase, putative; Belongs to the phosphohexose mutase family. (600 aa)
PURA1_TRYCCAdenylosuccinate synthetase 1; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). (616 aa)
Q4DLV1_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (198 aa)
Q4DM24_TRYCCAcidocalcisomal exopolyphosphatase, putative. (383 aa)
Q4DM82_TRYCCInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (512 aa)
Q4DNZ4_TRYCCAdenine phosphoribosyltransferase, putative. (235 aa)
Q4DPB1_TRYCCGuanylate kinase, putative. (206 aa)
Q4DQV0_TRYCCPhosphoglucomutase, putative; Belongs to the phosphohexose mutase family. (600 aa)
Q4DRC4_TRYCCHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (241 aa)
ITPA2_TRYCCInosine triphosphate pyrophosphatase 2; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
Q4DSS9_TRYCCRibose-phosphate pyrophosphokinase, putative. (705 aa)
Q4DUS4_TRYCCGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (452 aa)
Q4DVM8_TRYCCAdenine phosphoribosyltransferase, putative. (235 aa)
Q4DWB4_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (214 aa)
Q4DXL6_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (241 aa)
Q4DXL7_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (218 aa)
Q4DXW9_TRYCCPhosphoribosylpyrophosphate synthetase, putative. (362 aa)
Q4DYD7_TRYCCPhosphoribosylpyrophosphate synthetase, putative. (400 aa)
Q4DZ57_TRYCCAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (180 aa)
Q4E006_TRYCCPhosphodiesterase. (619 aa)
Q4E0S4_TRYCCAdenosine kinase, putative. (346 aa)
Q4E0Y5_TRYCCPhosphodiesterase. (929 aa)
Q4E0Y6_TRYCCPhosphodiesterase. (918 aa)
Q4E1D4_TRYCCGMP synthase, putative. (657 aa)
GMPR-2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (491 aa)
Q4E1S6_TRYCCAdenylate kinase, putative; Belongs to the adenylate kinase family. (260 aa)
Q4E1U3_TRYCCPyruvate kinase; Belongs to the pyruvate kinase family. (499 aa)
Q4E256_TRYCCNucleoside diphosphate kinase. (153 aa)
Q4E4D6_TRYCCGuanylate kinase, putative. (240 aa)
Q4E4G2_TRYCCAMP deaminase, putative. (1429 aa)
Q4E4R9_TRYCCNucleoside diphosphate kinase, putative. (334 aa)
Q4E627_TRYCCInosine-adenosine-guanosine-nucleoside hydrolase, putative. (326 aa)
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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