(47 nodes) Mixed, incl. Amine ligand-binding receptors, and GTPase complex network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_024868	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (723 aa)
	EOG090X08Y3	Viral iap-associated factor. (284 aa)
	APZ42_032647	Neuropeptide Y receptor type; Belongs to the G-protein coupled receptor 1 family. (550 aa)
	APZ42_014862	Putative Regulator of G-protein signaling 1. (226 aa)
	APZ42_015097	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (589 aa)
	APZ42_028368	5-hydroxytryptamine receptor 2B; Belongs to the G-protein coupled receptor 1 family. (634 aa)
	APZ42_030900	Neuropeptide Y receptor type; Belongs to the G-protein coupled receptor 1 family. (499 aa)
	APZ42_018047	Putative Class A rhodopsin G-protein-coupled receptor GPRnna8; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	APZ42_022515	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (566 aa)
	APZ42_019376	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
	APZ42_034456	Prostaglandin E2 receptor EP4 subtype. (426 aa)
	APZ42_011652	Regulator of G-protein signaling 17. (436 aa)
	APZ42_014497	Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (510 aa)
	APZ42_014481	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (64 aa)
	APZ42_011276	Putative Regulator of G-protein signaling 17. (2818 aa)
	APZ42_011769	Guanine nucleotide-binding protein G(O) subunit alpha 1. (354 aa)
	APZ42_008882	5-hydroxytryptamine receptor 1; Belongs to the G-protein coupled receptor 1 family. (167 aa)
	APZ42_001966	Class A rhodopsin G-protein-coupled receptor gprdop2. (104 aa)
	APZ42_032455	Guanine nucleotide binding protein, beta subunit. (349 aa)
	APZ42_032519	Synembryn. (518 aa)
	APZ42_032384	G_PROTEIN_RECEP_F1_2 domain-containing protein. (323 aa)
	APZ42_032380	Putative Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (488 aa)
	APZ42_031926	Putative Muscarinic acetylcholine receptor DM1. (259 aa)
	APZ42_031924	Putative Muscarinic acetylcholine receptor DM1. (679 aa)
	APZ42_031647	Putative Regulator of G-protein signaling 7. (557 aa)
	APZ42_028645	Putative 5-hydroxytryptamine receptor 1. (413 aa)
	APZ42_028760	Free fatty acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa)
	APZ42_028372	Putative Alpha-2B adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (310 aa)
	APZ42_026781	NPFG-protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (532 aa)
	APZ42_025954	Guanine nucleotide binding protein, beta subunit. (216 aa)
	APZ42_024498	Spermatogenesis-associated 13-like protein. (1403 aa)
	APZ42_024451	G-protein-signaling modulator 2. (661 aa)
	APZ42_024124	NPFG-protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	APZ42_022299	G-protein-coupled receptor No9; Belongs to the G-protein coupled receptor 1 family. (629 aa)
	APZ42_022566	Putative Regulator of G-protein signaling. (783 aa)
	APZ42_021907	Guanine nucleotide binding protein, beta subunit. (153 aa)
	APZ42_021891	Beta-arrestin-2. (844 aa)
	APZ42_021407	G-protein coupled receptor 84; Belongs to the G-protein coupled receptor 1 family. (484 aa)
	APZ42_021405	Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family. (510 aa)
	APZ42_021203	5-hydroxytryptamine receptor 1-like protein. (344 aa)
	APZ42_020935	Putative Muscarinic acetylcholine Receptor, B-type; Belongs to the G-protein coupled receptor 1 family. (909 aa)
	APZ42_020876	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (315 aa)
	APZ42_020451	Guanine nucleotide-binding protein G(I) alpha-1 subunit. (364 aa)
	APZ42_017623	Putative G-protein coupled receptor 101. (549 aa)
	APZ42_016948	Polyprenol reductase. (721 aa)
	APZ42_016373	G_PROTEIN_RECEP_F1_2 domain-containing protein. (385 aa)
	APZ42_016259	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (421 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001966	APZ42_008882	A0A164ILW2	A0A164ECN2	Class A rhodopsin G-protein-coupled receptor gprdop2.	5-hydroxytryptamine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.557
APZ42_001966	APZ42_011769	A0A164ILW2	A0A162SZC2	Class A rhodopsin G-protein-coupled receptor gprdop2.	Guanine nucleotide-binding protein G(O) subunit alpha 1.	0.673
APZ42_001966	APZ42_014481	A0A164ILW2	A0A162PUD0	Class A rhodopsin G-protein-coupled receptor gprdop2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.647
APZ42_001966	APZ42_014497	A0A164ILW2	A0A162PU82	Class A rhodopsin G-protein-coupled receptor gprdop2.	Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.405
APZ42_001966	APZ42_015097	A0A164ILW2	A0A0P5YZI9	Class A rhodopsin G-protein-coupled receptor gprdop2.	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	0.835
APZ42_001966	APZ42_016259	A0A164ILW2	A0A165AIN5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.475
APZ42_001966	APZ42_016373	A0A164ILW2	A0A165ADU2	Class A rhodopsin G-protein-coupled receptor gprdop2.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.524
APZ42_001966	APZ42_017623	A0A164ILW2	A0A164ZZ25	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative G-protein coupled receptor 101.	0.609
APZ42_001966	APZ42_018047	A0A164ILW2	A0A0P6CDF0	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor GPRnna8; Belongs to the G-protein coupled receptor 1 family.	0.648
APZ42_001966	APZ42_019376	A0A164ILW2	A0A0P6HZH0	Class A rhodopsin G-protein-coupled receptor gprdop2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.641
APZ42_001966	APZ42_020451	A0A164ILW2	A0A164XHW3	Class A rhodopsin G-protein-coupled receptor gprdop2.	Guanine nucleotide-binding protein G(I) alpha-1 subunit.	0.673
APZ42_001966	APZ42_020876	A0A164ILW2	A0A164X5L5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.482
APZ42_001966	APZ42_021203	A0A164ILW2	A0A164WVF0	Class A rhodopsin G-protein-coupled receptor gprdop2.	5-hydroxytryptamine receptor 1-like protein.	0.678
APZ42_001966	APZ42_021405	A0A164ILW2	A0A164WNP0	Class A rhodopsin G-protein-coupled receptor gprdop2.	Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family.	0.575
APZ42_001966	APZ42_021407	A0A164ILW2	A0A164WNM4	Class A rhodopsin G-protein-coupled receptor gprdop2.	G-protein coupled receptor 84; Belongs to the G-protein coupled receptor 1 family.	0.764
APZ42_001966	APZ42_021891	A0A164ILW2	A0A164W942	Class A rhodopsin G-protein-coupled receptor gprdop2.	Beta-arrestin-2.	0.604
APZ42_001966	APZ42_021907	A0A164ILW2	A0A164W8L6	Class A rhodopsin G-protein-coupled receptor gprdop2.	Guanine nucleotide binding protein, beta subunit.	0.726
APZ42_001966	APZ42_022515	A0A164ILW2	A0A0P6G8F0	Class A rhodopsin G-protein-coupled receptor gprdop2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.632
APZ42_001966	APZ42_024124	A0A164ILW2	A0A164UGJ8	Class A rhodopsin G-protein-coupled receptor gprdop2.	NPFG-protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family.	0.699
APZ42_001966	APZ42_024868	A0A164ILW2	A0A0P5DLX0	Class A rhodopsin G-protein-coupled receptor gprdop2.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.539