(55 nodes) Mixed, incl. Golgi Associated Vesicle Biogenesis, and Cargo adaptor activity network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_023452	Store-operated calcium entry-associated regulatory factor. (336 aa)
	APZ42_026855	Sorting nexin-17. (460 aa)
	APZ42_031704	AP-3 complex subunit sigma-2. (189 aa)
	APZ42_028247	Arf-GAP domain and FG repeat-containing 1-like protein. (499 aa)
	APZ42_026055	RalBP1-associated Eps domain-containing protein. (592 aa)
	EOG090X0GN3	Sorting nexin-12. (161 aa)
	APZ42_024908	AP-3 complex subunit delta-1. (1215 aa)
	APZ42_011067	Sorting nexin-4. (441 aa)
	APZ42_015608	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	APZ42_024201	AP-1 complex subunit gamma. (912 aa)
	APZ42_017011	Sorting nexin-2. (527 aa)
	APZ42_032183	Putative AP2-associated protein kinase. (692 aa)
	EOG090X00QE	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (811 aa)
	APZ42_018524	60S ribosomal export protein NMD3. (541 aa)
	APZ42_016617	Putative Sorting nexin-5. (352 aa)
	APZ42_015545	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
	APZ42_020788	AP complex subunit beta. (927 aa)
	APZ42_020867	Sorting nexin; Belongs to the sorting nexin family. (540 aa)
	APZ42_020216	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_029329	Putative Huntingtin interacting protein 1. (1369 aa)
	APZ42_026018	Vesicle-associated membrane protein 7. (133 aa)
	APZ42_025807	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (183 aa)
	APZ42_016099	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APZ42_015734	Uncharacterized protein. (263 aa)
	APZ42_015724	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1060 aa)
	APZ42_013830	Putative Stonin-1. (1840 aa)
	APZ42_013654	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	APZ42_011852	Amphiphysin. (341 aa)
	APZ42_011653	Bridging integrator 3. (269 aa)
	APZ42_008838	Putative Sorting nexin-6. (85 aa)
	APZ42_003352	Coactosin-like protein. (162 aa)
	APZ42_003320	Putative Huntingtin-interacting protein 1. (187 aa)
	APZ42_002399	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (349 aa)
	APZ42_001149	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta. (194 aa)
	APZ42_001089	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (118 aa)
	APZ42_000407	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (268 aa)
	APZ42_033656	Sorting nexin-30. (436 aa)
	APZ42_032189	Numb-associated kinase. (400 aa)
	APZ42_031695	Putative RalA-binding protein 1. (636 aa)
	APZ42_028960	Cyclin-G-associated kinase. (824 aa)
	APZ42_028262	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (95 aa)
	APZ42_028067	FCH domain only protein 2. (995 aa)
	APZ42_025631	Putative Amphiphysin. (139 aa)
	APZ42_025349	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2067 aa)
	APZ42_024220	ADP ribosylation factor 6-like protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	EOG090X05H4	Vacuolar protein sorting-associated protein 26. (370 aa)
	APZ42_022618	Sorting nexin; Involved in several stages of intracellular trafficking. (408 aa)
	APZ42_022686	Dynamin. (531 aa)
	APZ42_021745	Protein TBRG4. (602 aa)
	APZ42_021392	NECAP-like protein. (276 aa)
	APZ42_021443	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (415 aa)
	APZ42_019116	Phosphatidylinositol-binding clathrin assembly protein. (431 aa)
	APZ42_016707	Dynamin-binding protein. (1362 aa)
	APZ42_016272	Putative Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (523 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000407	APZ42_001089	A0A164JP86	A0A164J6I4	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.929
APZ42_000407	APZ42_002399	A0A164JP86	A0A164IAD9	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.445
APZ42_000407	APZ42_013654	A0A164JP86	A0A162QPP9	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.462
APZ42_000407	APZ42_015608	A0A164JP86	A0A0P5KQ01	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.929
APZ42_000407	APZ42_015724	A0A164JP86	A0A162NQ33	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.993
APZ42_000407	APZ42_016099	A0A164JP86	A0A162NMK5	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.494
APZ42_000407	APZ42_018911	A0A164JP86	A0A162CQ61	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.504
APZ42_000407	APZ42_020788	A0A164JP86	A0A0P6DXK2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.432
APZ42_000407	APZ42_021443	A0A164JP86	A0A164WPI1	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.696
APZ42_000407	APZ42_024201	A0A164JP86	A0A0P5LLS2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.937
APZ42_000407	APZ42_024908	A0A164JP86	A0A0P5HJ14	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit delta-1.	0.996
APZ42_000407	APZ42_031704	A0A164JP86	A0A0P4XAP2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit sigma-2.	0.988
APZ42_001089	APZ42_000407	A0A164J6I4	A0A164JP86	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.929
APZ42_001089	APZ42_015608	A0A164J6I4	A0A0P5KQ01	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.894
APZ42_001089	APZ42_015724	A0A164J6I4	A0A162NQ33	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.990
APZ42_001089	APZ42_021443	A0A164J6I4	A0A164WPI1	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.544
APZ42_001089	APZ42_024201	A0A164J6I4	A0A0P5LLS2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.905
APZ42_001089	APZ42_024908	A0A164J6I4	A0A0P5HJ14	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit delta-1.	0.995
APZ42_001089	APZ42_031704	A0A164J6I4	A0A0P4XAP2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit sigma-2.	0.982
APZ42_001149	APZ42_002399	A0A164J581	A0A164IAD9	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.568