(6 nodes) Retromer complex network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EOG090X0GN3	Sorting nexin-12. (161 aa)
	APZ42_017011	Sorting nexin-2. (527 aa)
	EOG090X00QE	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (811 aa)
	APZ42_018524	60S ribosomal export protein NMD3. (541 aa)
	APZ42_025807	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (183 aa)
	EOG090X05H4	Vacuolar protein sorting-associated protein 26. (370 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_017011	APZ42_025807	A0A0P5ME33	A0A162EEN0	Sorting nexin-2.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.989
APZ42_017011	EOG090X00QE	A0A0P5ME33	A0A0P5P8Q8	Sorting nexin-2.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.990
APZ42_017011	EOG090X05H4	A0A0P5ME33	A0A164UXL5	Sorting nexin-2.	Vacuolar protein sorting-associated protein 26.	0.984
APZ42_017011	EOG090X0GN3	A0A0P5ME33	A0A0P5FHN5	Sorting nexin-2.	Sorting nexin-12.	0.656
APZ42_018524	APZ42_025807	A0A0P5T322	A0A162EEN0	60S ribosomal export protein NMD3.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.824
APZ42_018524	EOG090X00QE	A0A0P5T322	A0A0P5P8Q8	60S ribosomal export protein NMD3.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.856
APZ42_018524	EOG090X05H4	A0A0P5T322	A0A164UXL5	60S ribosomal export protein NMD3.	Vacuolar protein sorting-associated protein 26.	0.775
APZ42_018524	EOG090X0GN3	A0A0P5T322	A0A0P5FHN5	60S ribosomal export protein NMD3.	Sorting nexin-12.	0.987
APZ42_025807	APZ42_017011	A0A162EEN0	A0A0P5ME33	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin-2.	0.989
APZ42_025807	APZ42_018524	A0A162EEN0	A0A0P5T322	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	60S ribosomal export protein NMD3.	0.824
APZ42_025807	EOG090X00QE	A0A162EEN0	A0A0P5P8Q8	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.999
APZ42_025807	EOG090X05H4	A0A162EEN0	A0A164UXL5	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Vacuolar protein sorting-associated protein 26.	0.999
APZ42_025807	EOG090X0GN3	A0A162EEN0	A0A0P5FHN5	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin-12.	0.892
EOG090X00QE	APZ42_017011	A0A0P5P8Q8	A0A0P5ME33	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Sorting nexin-2.	0.990
EOG090X00QE	APZ42_018524	A0A0P5P8Q8	A0A0P5T322	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	60S ribosomal export protein NMD3.	0.856
EOG090X00QE	APZ42_025807	A0A0P5P8Q8	A0A162EEN0	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.999
EOG090X00QE	EOG090X05H4	A0A0P5P8Q8	A0A164UXL5	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Vacuolar protein sorting-associated protein 26.	0.999
EOG090X00QE	EOG090X0GN3	A0A0P5P8Q8	A0A0P5FHN5	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Sorting nexin-12.	0.993
EOG090X05H4	APZ42_017011	A0A164UXL5	A0A0P5ME33	Vacuolar protein sorting-associated protein 26.	Sorting nexin-2.	0.984
EOG090X05H4	APZ42_018524	A0A164UXL5	A0A0P5T322	Vacuolar protein sorting-associated protein 26.	60S ribosomal export protein NMD3.	0.775