(35 nodes) Autophagy - other, and Mitochondrion disassembly network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_032732	WD repeat domain phosphoinositide-interacting protein 4. (348 aa)
	APZ42_026848	Serine/threonine-protein kinase ULK2. (869 aa)
	APZ42_017319	TBC1 domain family member 13. (671 aa)
	APZ42_019530	Nuclear receptor-binding factor 2. (220 aa)
	APZ42_021015	Autophagy-related protein 16-1. (378 aa)
	EOG090X0BB3	Autophagy protein 5; Involved in autophagic vesicle formation. (271 aa)
	APZ42_030931	Microtubule-associated proteins 1A/1B light chain 3A. (123 aa)
	APZ42_030853	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
	APZ42_019859	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (700 aa)
	APZ42_011181	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (454 aa)
	APZ42_012857	Autophagy-related protein 101. (222 aa)
	APZ42_014338	WD repeat domain phosphoinositide-interacting protein 2. (444 aa)
	EOG090X0AKX	Autophagy-related protein 3. (318 aa)
	APZ42_030312	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (758 aa)
	APZ42_020812	Ubiquitin-conjugating enzyme ATG10-like protein. (211 aa)
	APZ42_019518	BCL2/adenovirus E1B 19 kDa protein-interacting protein. (203 aa)
	APZ42_018829	RB1-inducible coiled-coil protein. (1116 aa)
	APZ42_014549	Phosphoinositide 3-kinase regulatory subunit 4. (1359 aa)
	APZ42_011510	Uncharacterized protein. (563 aa)
	APZ42_008992	Protein kinase domain-containing protein. (99 aa)
	EOG090X048D	Beclin-1-like protein. (441 aa)
	APZ42_033673	Autophagy-related 8a. (237 aa)
	APZ42_033416	Serine/threonine-protein kinase ULK3; Belongs to the protein kinase superfamily. (487 aa)
	APZ42_030693	Autophagy protein 5; Involved in autophagic vesicle formation. (71 aa)
	APZ42_029279	Autophagy-related 8a. (117 aa)
	APZ42_028571	Activating molecule in BECN1-regulated autophagy 1-like protein. (1394 aa)
	APZ42_026924	N_BRCA1_IG domain-containing protein. (227 aa)
	APZ42_025083	Autophagy-related protein 2 A. (1562 aa)
	APZ42_025084	Autophagy-related protein 2 A. (429 aa)
	APZ42_021580	Putative FUN14 domain-containing protein 1. (120 aa)
	APZ42_020991	Autophagy-related protein 16-1. (212 aa)
	APZ42_021131	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (230 aa)
	APZ42_020223	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (149 aa)
	APZ42_019653	Beclin 1-associated autophagy-related key regulator. (462 aa)
	APZ42_017964	Phosphatidylinositol 3-kinase catalytic subunit type 3. (910 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_008992	APZ42_011181	A0A164EA56	A0A0P5Z0K4	Protein kinase domain-containing protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.962
APZ42_008992	APZ42_012857	A0A164EA56	A0A0P5ZK01	Protein kinase domain-containing protein.	Autophagy-related protein 101.	0.909
APZ42_008992	APZ42_014338	A0A164EA56	A0A0P6D3J7	Protein kinase domain-containing protein.	WD repeat domain phosphoinositide-interacting protein 2.	0.867
APZ42_008992	APZ42_014549	A0A164EA56	A0A162PQ88	Protein kinase domain-containing protein.	Phosphoinositide 3-kinase regulatory subunit 4.	0.965
APZ42_008992	APZ42_017964	A0A164EA56	A0A164ZGM4	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.966
APZ42_008992	APZ42_018829	A0A164EA56	A0A162CPY9	Protein kinase domain-containing protein.	RB1-inducible coiled-coil protein.	0.960
APZ42_008992	APZ42_019530	A0A164EA56	A0A0P5B9R7	Protein kinase domain-containing protein.	Nuclear receptor-binding factor 2.	0.866
APZ42_008992	APZ42_019653	A0A164EA56	A0A164YCB1	Protein kinase domain-containing protein.	Beclin 1-associated autophagy-related key regulator.	0.893
APZ42_008992	APZ42_019859	A0A164EA56	A0A0P5SQA0	Protein kinase domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.516
APZ42_008992	APZ42_020991	A0A164EA56	A0A164WWB9	Protein kinase domain-containing protein.	Autophagy-related protein 16-1.	0.773
APZ42_008992	APZ42_021015	A0A164EA56	A0A0P5CB86	Protein kinase domain-containing protein.	Autophagy-related protein 16-1.	0.773
APZ42_008992	APZ42_021131	A0A164EA56	A0A164X197	Protein kinase domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.801
APZ42_008992	APZ42_021580	A0A164EA56	A0A164WJP9	Protein kinase domain-containing protein.	Putative FUN14 domain-containing protein 1.	0.725
APZ42_008992	APZ42_025083	A0A164EA56	A0A164TG66	Protein kinase domain-containing protein.	Autophagy-related protein 2 A.	0.907
APZ42_008992	APZ42_025084	A0A164EA56	A0A164TGA1	Protein kinase domain-containing protein.	Autophagy-related protein 2 A.	0.907
APZ42_008992	APZ42_028571	A0A164EA56	A0A164Q5X1	Protein kinase domain-containing protein.	Activating molecule in BECN1-regulated autophagy 1-like protein.	0.594
APZ42_008992	APZ42_029279	A0A164EA56	A0A164PTL5	Protein kinase domain-containing protein.	Autophagy-related 8a.	0.873
APZ42_008992	APZ42_030312	A0A164EA56	A0A0P6GFI4	Protein kinase domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.967
APZ42_008992	APZ42_030693	A0A164EA56	A0A164NHN9	Protein kinase domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.771
APZ42_008992	APZ42_030853	A0A164EA56	A0A0P5S5Q6	Protein kinase domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.801