(74 nodes) Mixed, incl. Cellular amino acid catabolic process, and Alpha-amino acid biosynthetic process network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_033870	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (547 aa)
	APZ42_012423	Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family. (495 aa)
	APZ42_027073	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (167 aa)
	APZ42_018780	Glutamine synthetase. (366 aa)
	APZ42_034177	Gasp. (333 aa)
	APZ42_018096	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial. (431 aa)
	APZ42_028234	Sarcosine dehydrogenase, mitochondrial. (904 aa)
	APZ42_013431	Aromatic-L-amino-acid decarboxylase. (475 aa)
	APZ42_033283	Alpha-aminoadipic semialdehyde synthase, mitochondrial. (952 aa)
	APZ42_015422	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa)
	APZ42_016440	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (278 aa)
	APZ42_019023	Trimethyllysine dioxygenase, mitochondrial. (421 aa)
	APZ42_022182	Glycine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. (288 aa)
	APZ42_033483	Phosphoserine phosphatase. (224 aa)
	APZ42_029167	Putative Transferase CAF17, mitochondrial. (327 aa)
	APZ42_018846	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (543 aa)
	APZ42_021785	Phosphoserine aminotransferase. (362 aa)
	APZ42_026541	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
	APZ42_030079	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (404 aa)
	APZ42_004213	Putative Retinal dehydrogenase 1. (109 aa)
	APZ42_019999	Glutamate synthase. (2078 aa)
	APZ42_019312	Alanine aminotransferase 2. (325 aa)
	APZ42_003025	Pyr_redox_2 domain-containing protein. (170 aa)
	APZ42_026291	4-trimethylaminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (470 aa)
	APZ42_003967	Putative Glycine cleavage system H protein. (49 aa)
	APZ42_015062	Cysteine sulfinic acid decarboxylase. (141 aa)
	APZ42_013661	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (468 aa)
	APZ42_013338	Fatty-acid amide hydrolase 2. (164 aa)
	APZ42_013122	Serine--pyruvate aminotransferase. (392 aa)
	APZ42_012624	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (275 aa)
	APZ42_012148	Phenoloxidase subunit A3. (587 aa)
	APZ42_011666	Asparagine synthetase domain-containing protein. (575 aa)
	APZ42_010997	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1. (475 aa)
	APZ42_009258	Putative Glycine dehydrogenase. (99 aa)
	APZ42_007862	TauD domain-containing protein. (98 aa)
	APZ42_004944	Uncharacterized protein. (152 aa)
	APZ42_004464	Putative Retinal dehydrogenase 1. (91 aa)
	APZ42_004423	DNA ligase 1. (146 aa)
	APZ42_004016	Aldehyde dehydrogenase family 7 member A1. (73 aa)
	APZ42_003286	Glutamine synthetase; Belongs to the glutamine synthetase family. (238 aa)
	APZ42_003276	Ornithine aminotransferase-like protein. (249 aa)
	APZ42_003220	Putative Phosphoserine aminotransferase. (131 aa)
	APZ42_003043	Uncharacterized protein. (111 aa)
	APZ42_002595	Putative Glutamate synthase. (154 aa)
	APZ42_002451	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (197 aa)
	APZ42_002154	Delta-1-pyrroline-5-carboxylate dehydrogenase-like protein. (189 aa)
	APZ42_002107	Putative Glutamate synthase. (143 aa)
	APZ42_001985	Putative Glycine dehydrogenase. (249 aa)
	APZ42_000249	Uncharacterized protein. (113 aa)
	APZ42_033975	L-asparaginase. (742 aa)
	APZ42_032137	Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
	APZ42_030703	Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (454 aa)
	APZ42_028025	Alanine--glyoxylate aminotransferase. (226 aa)
	APZ42_027074	Sarcosine dehydrogenase, mitochondrial. (941 aa)
	APZ42_026943	Putative Aldehyde dehydrogenase family 7 member A1; Belongs to the aldehyde dehydrogenase family. (496 aa)
	APZ42_025987	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (576 aa)
	APZ42_025545	Haloacid dehalogenase-like hydrolase domain-containing protein 3. (113 aa)
	APZ42_024494	L-allo-threonine aldolase. (389 aa)
	APZ42_024553	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (539 aa)
	APZ42_024453	Trimethyllysine dioxygenase, mitochondrial. (428 aa)
	APZ42_023746	Glutaminase kidney. (306 aa)
	APZ42_023678	Apoptosis-inducing factor 3. (590 aa)
	APZ42_022327	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (839 aa)
	APZ42_022792	Glutamate decarboxylase. (513 aa)
	APZ42_022152	Aromatic-L-amino-acid decarboxylase. (524 aa)
	APZ42_021035	Trimethyllysine dioxygenase, mitochondrial. (433 aa)
	APZ42_020917	Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa)
	APZ42_020541	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (530 aa)
	APZ42_020615	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (460 aa)
	APZ42_019194	Alanine--glyoxylate aminotransferase. (146 aa)
	APZ42_018089	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1006 aa)
	APZ42_017446	Aminoglycoside phosphotransferase domain-containing protein 1. (271 aa)
	APZ42_017553	Uncharacterized protein. (246 aa)
	APZ42_016804	D-aspartate oxidase. (344 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000249	APZ42_002107	A0A164JT98	A0A164II36	Uncharacterized protein.	Putative Glutamate synthase.	0.909
APZ42_000249	APZ42_002154	A0A164JT98	A0A164IGV6	Uncharacterized protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase-like protein.	0.546
APZ42_000249	APZ42_002451	A0A164JT98	A0A164I942	Uncharacterized protein.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.544
APZ42_000249	APZ42_002595	A0A164JT98	A0A164I660	Uncharacterized protein.	Putative Glutamate synthase.	0.909
APZ42_000249	APZ42_003025	A0A164JT98	A0A162CXJ8	Uncharacterized protein.	Pyr_redox_2 domain-containing protein.	0.909
APZ42_000249	APZ42_003043	A0A164JT98	A0A164HVF3	Uncharacterized protein.	Uncharacterized protein.	0.639
APZ42_000249	APZ42_003276	A0A164JT98	A0A164HNE6	Uncharacterized protein.	Ornithine aminotransferase-like protein.	0.510
APZ42_000249	APZ42_003286	A0A164JT98	A0A164HN34	Uncharacterized protein.	Glutamine synthetase; Belongs to the glutamine synthetase family.	0.661
APZ42_000249	APZ42_003967	A0A164JT98	A0A162F172	Uncharacterized protein.	Putative Glycine cleavage system H protein.	0.549
APZ42_000249	APZ42_004016	A0A164JT98	A0A164HAW7	Uncharacterized protein.	Aldehyde dehydrogenase family 7 member A1.	0.546
APZ42_000249	APZ42_004213	A0A164JT98	A0A162C147	Uncharacterized protein.	Putative Retinal dehydrogenase 1.	0.549
APZ42_000249	APZ42_004423	A0A164JT98	A0A164H2M3	Uncharacterized protein.	DNA ligase 1.	0.598
APZ42_000249	APZ42_004464	A0A164JT98	A0A164H1G0	Uncharacterized protein.	Putative Retinal dehydrogenase 1.	0.546
APZ42_000249	APZ42_004944	A0A164JT98	A0A164GR97	Uncharacterized protein.	Uncharacterized protein.	0.598
APZ42_000249	APZ42_011666	A0A164JT98	A0A162SX85	Uncharacterized protein.	Asparagine synthetase domain-containing protein.	0.792
APZ42_000249	APZ42_012423	A0A164JT98	A0A0N8CZK6	Uncharacterized protein.	Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family.	0.549
APZ42_000249	APZ42_013338	A0A164JT98	A0A162QX08	Uncharacterized protein.	Fatty-acid amide hydrolase 2.	0.453
APZ42_000249	APZ42_013661	A0A164JT98	A0A162QQA6	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.562
APZ42_000249	APZ42_015422	A0A164JT98	A0A0P5KBS5	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.562
APZ42_000249	APZ42_016804	A0A164JT98	A0A165A6D6	Uncharacterized protein.	D-aspartate oxidase.	0.545