(16 nodes) Mixed, incl. The canonical retinoid cycle in rods (twilight vision), and Villin/Gelsolin network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_030077	Epidermal growth factor receptor kinase substrate 8 2-like protein. (829 aa)
	APZ42_011834	Harmonin usher syndrome protein pdz domain-containing protein. (475 aa)
	APZ42_028239	Fascin. (508 aa)
	APZ42_014449	Myosin-rhogap protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (513 aa)
	APZ42_012813	Putative Usher Syndrome type-1G protein. (359 aa)
	APZ42_012792	Gelsolin. (937 aa)
	APZ42_011821	Myosin-XV-like protein. (292 aa)
	APZ42_032699	Putative Glutaredoxin domain-containing cysteine-rich protein 1. (469 aa)
	APZ42_032294	Villin-1. (680 aa)
	APZ42_029504	Twinfilin. (320 aa)
	APZ42_027647	Putative Myosin-XV. (102 aa)
	APZ42_026765	MAGUK p55 subfamily member 6; Belongs to the MAGUK family. (1302 aa)
	APZ42_025082	Putative Myosin-XV. (115 aa)
	APZ42_024646	Putative Myosin-XV. (114 aa)
	APZ42_022323	Myosin 10A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3016 aa)
	APZ42_016911	ANK_REP_REGION domain-containing protein. (1525 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_011821	APZ42_011834	A0A162T104	A0A0P5CI63	Myosin-XV-like protein.	Harmonin usher syndrome protein pdz domain-containing protein.	0.705
APZ42_011821	APZ42_012813	A0A162T104	A0A162RD95	Myosin-XV-like protein.	Putative Usher Syndrome type-1G protein.	0.783
APZ42_011821	APZ42_016911	A0A162T104	A0A165A8I3	Myosin-XV-like protein.	ANK_REP_REGION domain-containing protein.	0.482
APZ42_011821	APZ42_028239	A0A162T104	A0A0P5Y7P1	Myosin-XV-like protein.	Fascin.	0.416
APZ42_011821	APZ42_029504	A0A162T104	A0A164PMP6	Myosin-XV-like protein.	Twinfilin.	0.428
APZ42_011821	APZ42_030077	A0A162T104	A0A0N8AG32	Myosin-XV-like protein.	Epidermal growth factor receptor kinase substrate 8 2-like protein.	0.416
APZ42_011821	APZ42_032699	A0A162T104	A0A164LTM9	Myosin-XV-like protein.	Putative Glutaredoxin domain-containing cysteine-rich protein 1.	0.417
APZ42_011834	APZ42_011821	A0A0P5CI63	A0A162T104	Harmonin usher syndrome protein pdz domain-containing protein.	Myosin-XV-like protein.	0.705
APZ42_011834	APZ42_012813	A0A0P5CI63	A0A162RD95	Harmonin usher syndrome protein pdz domain-containing protein.	Putative Usher Syndrome type-1G protein.	0.984
APZ42_011834	APZ42_014449	A0A0P5CI63	A0A162PVU0	Harmonin usher syndrome protein pdz domain-containing protein.	Myosin-rhogap protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.705
APZ42_011834	APZ42_016911	A0A0P5CI63	A0A165A8I3	Harmonin usher syndrome protein pdz domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.619
APZ42_011834	APZ42_022323	A0A0P5CI63	A0A164VFL2	Harmonin usher syndrome protein pdz domain-containing protein.	Myosin 10A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.705
APZ42_011834	APZ42_024646	A0A0P5CI63	A0A164TVN3	Harmonin usher syndrome protein pdz domain-containing protein.	Putative Myosin-XV.	0.705
APZ42_011834	APZ42_025082	A0A0P5CI63	A0A164TH60	Harmonin usher syndrome protein pdz domain-containing protein.	Putative Myosin-XV.	0.705
APZ42_011834	APZ42_026765	A0A0P5CI63	A0A164RXY4	Harmonin usher syndrome protein pdz domain-containing protein.	MAGUK p55 subfamily member 6; Belongs to the MAGUK family.	0.547
APZ42_011834	APZ42_027647	A0A0P5CI63	A0A164R5Q6	Harmonin usher syndrome protein pdz domain-containing protein.	Putative Myosin-XV.	0.705
APZ42_011834	APZ42_032699	A0A0P5CI63	A0A164LTM9	Harmonin usher syndrome protein pdz domain-containing protein.	Putative Glutaredoxin domain-containing cysteine-rich protein 1.	0.513
APZ42_012792	APZ42_016911	A0A162REA6	A0A165A8I3	Gelsolin.	ANK_REP_REGION domain-containing protein.	0.557
APZ42_012792	APZ42_026765	A0A162REA6	A0A164RXY4	Gelsolin.	MAGUK p55 subfamily member 6; Belongs to the MAGUK family.	0.557
APZ42_012792	APZ42_029504	A0A162REA6	A0A164PMP6	Gelsolin.	Twinfilin.	0.746