(52 nodes) Mixed, incl. Notch signaling pathway, and Growth factor receptor cysteine-rich domain superfamily network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_033022	Uncharacterized protein. (801 aa)
	APZ42_014221	Fibrillin-1. (2648 aa)
	APZ42_022249	Uncharacterized protein. (494 aa)
	APZ42_019025	Gamma-secretase subunit PEN-2. (101 aa)
	APZ42_026609	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (378 aa)
	APZ42_023831	Gamma-secretase subunit Aph-1b. (340 aa)
	APZ42_030672	Putative Homeodomain transcription factor. (873 aa)
	APZ42_022973	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (1667 aa)
	APZ42_031773	Neurogenic protein mastermind. (1345 aa)
	APZ42_025705	Putative Fibrillin-1. (1861 aa)
	APZ42_017443	Rhomboid 5 (RHBDF2), mRNA protein. (1665 aa)
	APZ42_027527	Neurogenic locus notch protein. (2566 aa)
	APZ42_015818	Putative Fibulin 1 and. (278 aa)
	APZ42_027608	Protein numb. (531 aa)
	APZ42_026628	Tetraspanin. (281 aa)
	APZ42_015430	Soldier-specific protein-1. (262 aa)
	APZ42_001912	Fibulin 1 and. (222 aa)
	APZ42_029401	Uncharacterized protein. (2113 aa)
	APZ42_028694	Disintegrin and metalloproteinase domain-containing protein 10. (585 aa)
	APZ42_025180	Putative Bifocal. (1125 aa)
	APZ42_025136	Delta-like protein. (148 aa)
	APZ42_023741	Thrombospondin. (1191 aa)
	APZ42_015395	Tissue inhibitor of metalloproteases. (244 aa)
	APZ42_014550	Protein sickie-like protein. (1933 aa)
	APZ42_014241	Uncharacterized protein. (1288 aa)
	APZ42_013401	Putative Complement component C1q receptor. (1255 aa)
	APZ42_013015	ADAM 17 Protease. (750 aa)
	APZ42_012740	Uncharacterized protein. (675 aa)
	APZ42_010236	Uncharacterized protein. (166 aa)
	APZ42_002555	Delta-like protein. (102 aa)
	APZ42_001983	Uncharacterized protein. (500 aa)
	APZ42_001737	Thyroglobulin type-1 domain-containing protein. (266 aa)
	APZ42_000788	Putative Recombining binding protein suppressor of hairless. (118 aa)
	APZ42_034059	Chitin-binding type-2 domain-containing protein. (636 aa)
	APZ42_032936	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (646 aa)
	APZ42_032773	Fibulin-5. (1994 aa)
	APZ42_031983	Uncharacterized protein. (1246 aa)
	APZ42_030990	Disintegrin and metalloproteinase domain-containing protein. (912 aa)
	APZ42_029432	Uncharacterized protein. (1751 aa)
	APZ42_029283	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (366 aa)
	APZ42_028781	Putative Fibulin 1 and. (261 aa)
	APZ42_026767	Nicastrin. (700 aa)
	APZ42_026814	Fibulin-5. (772 aa)
	APZ42_026872	Myosin-rhogap-like protein. (617 aa)
	APZ42_026713	Fibrillin-1-like protein. (647 aa)
	APZ42_023950	E3 ubiquitin-protein ligase. (872 aa)
	APZ42_022374	Uncharacterized protein. (2240 aa)
	APZ42_022683	Von Willebrand factor D and EGF domain-containing protein. (1392 aa)
	APZ42_022064	Delta-like protein. (797 aa)
	APZ42_021103	Uncharacterized protein. (814 aa)
	APZ42_018760	Uncharacterized protein. (1687 aa)
	APZ42_016321	Deltex protein. (238 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000788	APZ42_001737	A0A164JDM5	A0A164IS78	Putative Recombining binding protein suppressor of hairless.	Thyroglobulin type-1 domain-containing protein.	0.578
APZ42_000788	APZ42_001912	A0A164JDM5	A0A162CZM6	Putative Recombining binding protein suppressor of hairless.	Fibulin 1 and.	0.716
APZ42_000788	APZ42_001983	A0A164JDM5	A0A164ILE7	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.716
APZ42_000788	APZ42_002555	A0A164JDM5	A0A164I721	Putative Recombining binding protein suppressor of hairless.	Delta-like protein.	0.716
APZ42_000788	APZ42_010236	A0A164JDM5	A0A164DHM4	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.578
APZ42_000788	APZ42_013401	A0A164JDM5	A0A162QYS0	Putative Recombining binding protein suppressor of hairless.	Putative Complement component C1q receptor.	0.651
APZ42_000788	APZ42_014221	A0A164JDM5	A0A0N8C5D1	Putative Recombining binding protein suppressor of hairless.	Fibrillin-1.	0.716
APZ42_000788	APZ42_014241	A0A164JDM5	A0A162Q5F4	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.716
APZ42_000788	APZ42_014550	A0A164JDM5	A0A162PPX1	Putative Recombining binding protein suppressor of hairless.	Protein sickie-like protein.	0.665
APZ42_000788	APZ42_015430	A0A164JDM5	A0A0P6GF57	Putative Recombining binding protein suppressor of hairless.	Soldier-specific protein-1.	0.716
APZ42_000788	APZ42_015818	A0A164JDM5	A0A0P5YVL4	Putative Recombining binding protein suppressor of hairless.	Putative Fibulin 1 and.	0.716
APZ42_000788	APZ42_018760	A0A164JDM5	A0A164YSQ4	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.716
APZ42_000788	APZ42_021103	A0A164JDM5	A0A164WZ75	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.716
APZ42_000788	APZ42_022064	A0A164JDM5	A0A164W012	Putative Recombining binding protein suppressor of hairless.	Delta-like protein.	0.828
APZ42_000788	APZ42_022249	A0A164JDM5	A0A0N8DPI5	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.716
APZ42_000788	APZ42_022374	A0A164JDM5	A0A164VFT6	Putative Recombining binding protein suppressor of hairless.	Uncharacterized protein.	0.578
APZ42_000788	APZ42_022683	A0A164JDM5	A0A164VQU0	Putative Recombining binding protein suppressor of hairless.	Von Willebrand factor D and EGF domain-containing protein.	0.716
APZ42_000788	APZ42_022973	A0A164JDM5	A0A0P5TGJ2	Putative Recombining binding protein suppressor of hairless.	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family.	0.828
APZ42_000788	APZ42_023741	A0A164JDM5	A0A162DFK5	Putative Recombining binding protein suppressor of hairless.	Thrombospondin.	0.716
APZ42_000788	APZ42_025136	A0A164JDM5	A0A162DDU3	Putative Recombining binding protein suppressor of hairless.	Delta-like protein.	0.716