(11 nodes) Amyloid-beta formation, and Lateral inhibition network (Daphnia magna)

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	APZ42_019025	Gamma-secretase subunit PEN-2. (101 aa)
	APZ42_023831	Gamma-secretase subunit Aph-1b. (340 aa)
	APZ42_022973	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (1667 aa)
	APZ42_027608	Protein numb. (531 aa)
	APZ42_025136	Delta-like protein. (148 aa)
	APZ42_013401	Putative Complement component C1q receptor. (1255 aa)
	APZ42_032936	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (646 aa)
	APZ42_031983	Uncharacterized protein. (1246 aa)
	APZ42_029283	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (366 aa)
	APZ42_026767	Nicastrin. (700 aa)
	APZ42_022064	Delta-like protein. (797 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_013401	APZ42_019025	A0A162QYS0	A0A0P5JXM2	Putative Complement component C1q receptor.	Gamma-secretase subunit PEN-2.	0.529
APZ42_013401	APZ42_022064	A0A162QYS0	A0A164W012	Putative Complement component C1q receptor.	Delta-like protein.	0.570
APZ42_013401	APZ42_022973	A0A162QYS0	A0A0P5TGJ2	Putative Complement component C1q receptor.	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family.	0.522
APZ42_013401	APZ42_023831	A0A162QYS0	A0A0P5T543	Putative Complement component C1q receptor.	Gamma-secretase subunit Aph-1b.	0.778
APZ42_013401	APZ42_025136	A0A162QYS0	A0A162DDU3	Putative Complement component C1q receptor.	Delta-like protein.	0.522
APZ42_013401	APZ42_026767	A0A162QYS0	A0A164RX61	Putative Complement component C1q receptor.	Nicastrin.	0.783
APZ42_013401	APZ42_027608	A0A162QYS0	A0A0P5ZRL2	Putative Complement component C1q receptor.	Protein numb.	0.786
APZ42_013401	APZ42_029283	A0A162QYS0	A0A164PTR6	Putative Complement component C1q receptor.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.698
APZ42_013401	APZ42_032936	A0A162QYS0	A0A164LJ80	Putative Complement component C1q receptor.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.522
APZ42_019025	APZ42_013401	A0A0P5JXM2	A0A162QYS0	Gamma-secretase subunit PEN-2.	Putative Complement component C1q receptor.	0.529
APZ42_019025	APZ42_022064	A0A0P5JXM2	A0A164W012	Gamma-secretase subunit PEN-2.	Delta-like protein.	0.707
APZ42_019025	APZ42_022973	A0A0P5JXM2	A0A0P5TGJ2	Gamma-secretase subunit PEN-2.	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family.	0.707
APZ42_019025	APZ42_023831	A0A0P5JXM2	A0A0P5T543	Gamma-secretase subunit PEN-2.	Gamma-secretase subunit Aph-1b.	0.994
APZ42_019025	APZ42_025136	A0A0P5JXM2	A0A162DDU3	Gamma-secretase subunit PEN-2.	Delta-like protein.	0.568
APZ42_019025	APZ42_026767	A0A0P5JXM2	A0A164RX61	Gamma-secretase subunit PEN-2.	Nicastrin.	0.999
APZ42_019025	APZ42_029283	A0A0P5JXM2	A0A164PTR6	Gamma-secretase subunit PEN-2.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.980
APZ42_019025	APZ42_031983	A0A0P5JXM2	A0A164MG04	Gamma-secretase subunit PEN-2.	Uncharacterized protein.	0.529
APZ42_019025	APZ42_032936	A0A0P5JXM2	A0A164LJ80	Gamma-secretase subunit PEN-2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.568
APZ42_022064	APZ42_013401	A0A164W012	A0A162QYS0	Delta-like protein.	Putative Complement component C1q receptor.	0.570
APZ42_022064	APZ42_019025	A0A164W012	A0A0P5JXM2	Delta-like protein.	Gamma-secretase subunit PEN-2.	0.707