(27 nodes) Mixed, incl. Small GTPase Rho, and Ephrin signaling network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EOG090X0EJY	Rho GDP-dissociation inhibitor 2. (203 aa)
	APZ42_019019	Cytoplasmic protein NCK1. (474 aa)
	APZ42_027313	Ras-related and estrogen-regulated growth inhibitor protein. (277 aa)
	APZ42_033256	Putative Rho guanine nucleotide exchange factor 7. (611 aa)
	APZ42_014495	Ras GTP-binding protein RhoL. (184 aa)
	APZ42_022105	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (770 aa)
	APZ42_026236	Ras-related C3 botulinum toxin substrate. (192 aa)
	APZ42_018359	Putative Rho-related GTP-binding protein RhoU. (308 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_020242	Nuclear cap-binding protein subunit. (313 aa)
	APZ42_021092	G protein-coupled receptor kinase interacting ArfGAP. (670 aa)
	APZ42_017917	Epidermal growth factor receptor substrate 15 1-like protein. (1834 aa)
	APZ42_024117	Rad, Gem/Kir family member 3. (593 aa)
	APZ42_026048	Putative Active breakpoint cluster region-related protein. (1145 aa)
	APZ42_024809	Non-specific serine/threonine protein kinase. (829 aa)
	APZ42_022107	Putative SH3 domain-containing RING finger protein 3. (805 aa)
	APZ42_027332	Unconventional myosin-IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2198 aa)
	APZ42_011802	Non-specific serine/threonine protein kinase. (595 aa)
	APZ42_016307	Non-specific serine/threonine protein kinase. (547 aa)
	APZ42_015191	Rho-related BTB domain-containing protein 2. (718 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_002146	Ras family protein member 10B. (230 aa)
	APZ42_028326	Ras GTPase-activating IQGAP3-like protein. (1613 aa)
	APZ42_025128	Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (2017 aa)
	APZ42_024503	Ras-related C3 botulinum toxin substrate. (195 aa)
	APZ42_018141	SLIT-ROBO Rho GTPase-activating protein 1. (672 aa)
	APZ42_017145	Uncharacterized protein. (1021 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002146	APZ42_004669	A0A164IH38	A0A164GWT3	Ras family protein member 10B.	Ras GTP-binding protein Rho1.	0.584
APZ42_002146	APZ42_011802	A0A164IH38	A0A0P6EQN6	Ras family protein member 10B.	Non-specific serine/threonine protein kinase.	0.673
APZ42_002146	APZ42_012615	A0A164IH38	A0A0P5KP21	Ras family protein member 10B.	Rho-related GTP-binding protein RhoF.	0.584
APZ42_002146	APZ42_014495	A0A164IH38	A0A0P5EG34	Ras family protein member 10B.	Ras GTP-binding protein RhoL.	0.566
APZ42_002146	APZ42_015191	A0A164IH38	A0A162P9H3	Ras family protein member 10B.	Rho-related BTB domain-containing protein 2.	0.566
APZ42_002146	APZ42_016307	A0A164IH38	A0A0P6HYT2	Ras family protein member 10B.	Non-specific serine/threonine protein kinase.	0.673
APZ42_002146	APZ42_017145	A0A164IH38	A0A164ZP02	Ras family protein member 10B.	Uncharacterized protein.	0.805
APZ42_002146	APZ42_017917	A0A164IH38	A0A0P5T7E4	Ras family protein member 10B.	Epidermal growth factor receptor substrate 15 1-like protein.	0.949
APZ42_002146	APZ42_018141	A0A164IH38	A0A164ZBB9	Ras family protein member 10B.	SLIT-ROBO Rho GTPase-activating protein 1.	0.559
APZ42_002146	APZ42_018359	A0A164IH38	A0A0P5J9Z3	Ras family protein member 10B.	Putative Rho-related GTP-binding protein RhoU.	0.566
APZ42_002146	APZ42_019019	A0A164IH38	A0A0P4XJV0	Ras family protein member 10B.	Cytoplasmic protein NCK1.	0.595
APZ42_002146	APZ42_021092	A0A164IH38	A0A0P5PSR0	Ras family protein member 10B.	G protein-coupled receptor kinase interacting ArfGAP.	0.494
APZ42_002146	APZ42_022105	A0A164IH38	A0A0P5F335	Ras family protein member 10B.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.612
APZ42_002146	APZ42_022107	A0A164IH38	A0A0P5YEQ6	Ras family protein member 10B.	Putative SH3 domain-containing RING finger protein 3.	0.704
APZ42_002146	APZ42_024503	A0A164IH38	A0A164TX58	Ras family protein member 10B.	Ras-related C3 botulinum toxin substrate.	0.566
APZ42_002146	APZ42_024809	A0A164IH38	A0A0P5WNT8	Ras family protein member 10B.	Non-specific serine/threonine protein kinase.	0.673
APZ42_002146	APZ42_025128	A0A164IH38	A0A164TF05	Ras family protein member 10B.	Dedicator of cytokinesis protein 5; Belongs to the DOCK family.	0.639
APZ42_002146	APZ42_026048	A0A164IH38	A0A0P5TLH6	Ras family protein member 10B.	Putative Active breakpoint cluster region-related protein.	0.615
APZ42_002146	APZ42_026236	A0A164IH38	A0A0P5IN29	Ras family protein member 10B.	Ras-related C3 botulinum toxin substrate.	0.566
APZ42_002146	APZ42_027332	A0A164IH38	A0A0P5ZFF5	Ras family protein member 10B.	Unconventional myosin-IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.788