(32 nodes) Transcription initiation from RNA polymerase II promoter network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	APZ42_015392	Transcription initiation factor TFIID subunit 8. (292 aa)
	APZ42_016450	Putative Transcription initiation factor TFIID subunit 4. (997 aa)
	APZ42_014754	Transcription initiation factor IIa subunit 1. (325 aa)
	APZ42_017207	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (280 aa)
	APZ42_027379	Transcription initiation factor TFIID subunit 6. (601 aa)
	EOG090X0BPM	CDK-activating kinase assembly factor MAT1. (344 aa)
	EOG090X0HZC	Transcription initiation factor TFIID subunit 12. (136 aa)
	APZ42_010999	General transcription factor IIE subunit 1. (422 aa)
	APZ42_014299	General transcription factor IIH subunit. (427 aa)
	APZ42_032789	Transcription initiation factor iib general transcription factor tfiib. (308 aa)
	APZ42_027296	Transcription initiation factor TFIID subunit 7. (376 aa)
	APZ42_018611	TFIIH basal transcription factor complex helicase XPD subunit. (760 aa)
	APZ42_028327	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (379 aa)
	APZ42_032266	Transcription initiation factor IIA subunit 2. (159 aa)
	APZ42_015656	Putative Transcription initiation factor TFIID subunit 3. (928 aa)
	EOG090X080D	EOG090X080D; Belongs to the cyclin family. (328 aa)
	APZ42_015388	TFIIH basal transcription factor complex helicase XPB subunit. (797 aa)
	APZ42_014775	TATA box binding protein-related factor. (236 aa)
	APZ42_011202	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (280 aa)
	APZ42_002910	Putative TATA box binding protein-related factor. (97 aa)
	APZ42_034382	Transcription initiation factor IIB. (319 aa)
	APZ42_029692	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
	APZ42_026818	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
	APZ42_026689	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (197 aa)
	APZ42_024009	Putative Transcription initiation factor TFIID subunit 2. (1846 aa)
	APZ42_024207	Transcription initiation factor TFIID subunit 5. (678 aa)
	APZ42_021138	General transcription factor IIH subunit 1. (567 aa)
	APZ42_021147	Putative Transcription initiation factor TFIID subunit 11. (261 aa)
	APZ42_019925	TATA box binding protein tbp-associated factor. (142 aa)
	APZ42_019453	Putative WD repeat-containing protein 3. (566 aa)
	APZ42_019320	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (546 aa)
	APZ42_016542	Transcription initiation factor TFIID subunit 1. (1826 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002910	APZ42_010999	A0A164HYK9	A0A0P5LGD3	Putative TATA box binding protein-related factor.	General transcription factor IIE subunit 1.	0.968
APZ42_002910	APZ42_011202	A0A164HYK9	A0A162SGS6	Putative TATA box binding protein-related factor.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.895
APZ42_002910	APZ42_014299	A0A164HYK9	A0A0P5VYR5	Putative TATA box binding protein-related factor.	General transcription factor IIH subunit.	0.941
APZ42_002910	APZ42_014754	A0A164HYK9	A0A0P4YM85	Putative TATA box binding protein-related factor.	Transcription initiation factor IIa subunit 1.	0.963
APZ42_002910	APZ42_015388	A0A164HYK9	A0A162PFH9	Putative TATA box binding protein-related factor.	TFIIH basal transcription factor complex helicase XPB subunit.	0.957
APZ42_002910	APZ42_015392	A0A164HYK9	A0A0N8AQ44	Putative TATA box binding protein-related factor.	Transcription initiation factor TFIID subunit 8.	0.957
APZ42_002910	APZ42_015656	A0A164HYK9	A0A162NTQ4	Putative TATA box binding protein-related factor.	Putative Transcription initiation factor TFIID subunit 3.	0.923
APZ42_002910	APZ42_016450	A0A164HYK9	A0A0P4YEW1	Putative TATA box binding protein-related factor.	Putative Transcription initiation factor TFIID subunit 4.	0.966
APZ42_002910	APZ42_016542	A0A164HYK9	A0A165AHB0	Putative TATA box binding protein-related factor.	Transcription initiation factor TFIID subunit 1.	0.966
APZ42_002910	APZ42_017207	A0A164HYK9	A0A0P4ZEP6	Putative TATA box binding protein-related factor.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.895
APZ42_002910	APZ42_018611	A0A164HYK9	A0A0P5YAY8	Putative TATA box binding protein-related factor.	TFIIH basal transcription factor complex helicase XPD subunit.	0.947
APZ42_002910	APZ42_019320	A0A164HYK9	A0A164YHV0	Putative TATA box binding protein-related factor.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.965
APZ42_002910	APZ42_019453	A0A164HYK9	A0A164Y5Z6	Putative TATA box binding protein-related factor.	Putative WD repeat-containing protein 3.	0.905
APZ42_002910	APZ42_019925	A0A164HYK9	A0A164XUE7	Putative TATA box binding protein-related factor.	TATA box binding protein tbp-associated factor.	0.965
APZ42_002910	APZ42_021138	A0A164HYK9	A0A164X0Z8	Putative TATA box binding protein-related factor.	General transcription factor IIH subunit 1.	0.950
APZ42_002910	APZ42_021147	A0A164HYK9	A0A164X125	Putative TATA box binding protein-related factor.	Putative Transcription initiation factor TFIID subunit 11.	0.965
APZ42_002910	APZ42_024009	A0A164HYK9	A0A164UE43	Putative TATA box binding protein-related factor.	Putative Transcription initiation factor TFIID subunit 2.	0.966
APZ42_002910	APZ42_024207	A0A164HYK9	A0A164UJL5	Putative TATA box binding protein-related factor.	Transcription initiation factor TFIID subunit 5.	0.905
APZ42_002910	APZ42_026689	A0A164HYK9	A0A164S3J2	Putative TATA box binding protein-related factor.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.875
APZ42_002910	APZ42_026818	A0A164HYK9	A0A164RYY7	Putative TATA box binding protein-related factor.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.875