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| | APZ42_018703 | F-box DNA helicase 1. (949 aa) |
| | EOG090X0906 | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (341 aa) |
| | APZ42_015316 | DNA repair protein RAD51. (317 aa) |
| | APZ42_028758 | E3 ubiquitin-protein ligase RAD18. (538 aa) |
| | APZ42_034386 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (703 aa) |
| | APZ42_018756 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (405 aa) |
| | APZ42_031507 | Breast and ovarian cancer sususceptibility protein. (952 aa) |
| | APZ42_017653 | Putative PAX-interacting protein 1. (1621 aa) |
| | APZ42_013319 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (520 aa) |
| | APZ42_026821 | Sister chromatid cohesion protein DCC1. (381 aa) |
| | APZ42_022013 | DNA repair protein RAD52. (385 aa) |
| | APZ42_016878 | DNA replication factor Cdt1. (705 aa) |
| | APZ42_022277 | Non-specific serine/threonine protein kinase. (2957 aa) |
| | APZ42_022372 | ATP-dependent DNA Helicase Q5-like protein. (1046 aa) |
| | APZ42_011418 | Replication protein A 32 kDa subunit. (268 aa) |
| | APZ42_031749 | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | APZ42_017973 | Meiotic recombination protein DMC1/LIM15. (358 aa) |
| | APZ42_019871 | Cell cycle checkpoint control protein; Belongs to the rad9 family. (404 aa) |
| | Fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa) |
| | APZ42_012437 | Replication factor C subunit 3. (328 aa) |
| | APZ42_027423 | DNA helicase; Belongs to the MCM family. (835 aa) |
| | APZ42_032613 | Replication protein A 14 kDa subunit. (111 aa) |
| | APZ42_026085 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (423 aa) |
| | APZ42_033980 | Replication factor C subunit 1. (1083 aa) |
| | EOG090X0G8U | DNA replication complex GINS protein PSF3. (202 aa) |
| | APZ42_015890 | Origin recognition complex subunit 3. (707 aa) |
| | APZ42_022929 | DNA polymerase. (1088 aa) |
| | APZ42_028709 | Meiosis-specific with OB domain-containing protein. (462 aa) |
| | APZ42_015342 | DNA helicase; Belongs to the MCM family. (843 aa) |
| | APZ42_001454 | Putative Oligonucleotide/oligosaccharide-binding fold-containing protein 1/sw. (194 aa) |
| | APZ42_015424 | Origin recognition complex subunit. (801 aa) |
| | APZ42_021862 | Putative DNA polymerase epsilon subunit 4. (128 aa) |
| | APZ42_014921 | Microcephalin. (599 aa) |
| | APZ42_013589 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa) |
| | APZ42_022932 | Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (985 aa) |
| | APZ42_028289 | Sensitized chromosome inheritance modifier. (747 aa) |
| | APZ42_010923 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa) |
| | APZ42_011399 | Chromosome transmission fidelity protein. (111 aa) |
| | APZ42_026407 | Meiotic recombination protein DMC1/LIM15. (323 aa) |
| | APZ42_009263 | Cell division control protein 6. (141 aa) |
| | APZ42_006332 | Putative DNA helicase bloom's syndrome protein A. (251 aa) |
| | APZ42_001557 | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (327 aa) |
| | APZ42_020922 | Chromosome transmission fidelity protein 18. (926 aa) |
| | APZ42_020612 | DNA replication ATP-dependent helicase/nuclease DNA2. (765 aa) |
| | APZ42_004333 | Replication factor C subunit 3. (331 aa) |
| | APZ42_028882 | DNA ligase. (816 aa) |
| | APZ42_032382 | Cell cycle checkpoint protein RAD1. (387 aa) |
| | APZ42_026490 | ATM/Rad3 and Mei-41-like protein; Belongs to the PI3/PI4-kinase family. (2568 aa) |
| | APZ42_015744 | Ovarian-specific serine/threonine-protein kinase Lok; Belongs to the protein kinase superfamily. (429 aa) |
| | APZ42_015932 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (662 aa) |
| | APZ42_014340 | Myotrophin. (770 aa) |
| | APZ42_013658 | BRCT domain-containing protein. (1286 aa) |
| | APZ42_012388 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | APZ42_011513 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1075 aa) |
| | APZ42_011549 | Geminin. (202 aa) |
| | APZ42_010927 | Replication factor C subunit 2. (288 aa) |
| | APZ42_010931 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (267 aa) |
| | APZ42_007681 | Uncharacterized protein. (112 aa) |
| | APZ42_005704 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (188 aa) |
| | APZ42_004672 | Cell division control protein 6. (115 aa) |
| | APZ42_003354 | Toprim domain-containing protein. (101 aa) |
| | APZ42_003073 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (165 aa) |
| | APZ42_002493 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (161 aa) |
| | APZ42_002389 | Uncharacterized protein. (147 aa) |
| | APZ42_000083 | Replication factor C subunit 4. (98 aa) |
| | APZ42_034515 | DNA repair protein RAD50; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (1342 aa) |
| | APZ42_034379 | DNA helicase; Belongs to the MCM family. (732 aa) |
| | APZ42_034445 | Putative MCM8, Minichromosome maintenance complex component 8; Belongs to the MCM family. (593 aa) |
| | APZ42_034246 | Putative DNA helicase bloom's syndrome protein A. (1291 aa) |
| | APZ42_034201 | Putative Cell cycle checkpoint protein RAD17. (298 aa) |
| | APZ42_033992 | Putative RecQ-mediated instability protein 1. (548 aa) |
| | APZ42_033270 | Origin recognition complex subunit 2. (340 aa) |
| | APZ42_033198 | DNA polymerase delta small subunit. (444 aa) |
| | APZ42_033162 | ResIII domain-containing protein. (262 aa) |
| | APZ42_032566 | Putative Cuticular protein 30F. (851 aa) |
| | APZ42_031776 | Putative TIMEOUT/TIM-2 protein. (509 aa) |
| | APZ42_031777 | Putative TIMEOUT/TIM-2 protein. (605 aa) |
| | APZ42_031574 | Reverse transcriptase domain-containing protein. (490 aa) |
| | APZ42_031273 | Replication factor C subunit 2. (344 aa) |
| | APZ42_031186 | CCHC-type domain-containing protein. (505 aa) |
| | APZ42_031140 | Bloom Syndrome-like protein. (415 aa) |
| | APZ42_031137 | Bloom Syndrome-like protein. (639 aa) |
| | APZ42_030620 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa) |
| | APZ42_030443 | Putative Nibrin. (610 aa) |
| | APZ42_030168 | Putative DNA polymerase epsilon subunit 3. (141 aa) |
| | APZ42_029471 | Uncharacterized protein. (1081 aa) |
| | APZ42_028351 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (698 aa) |
| | APZ42_028355 | Mini-chromosome maintenance complex-binding protein. (611 aa) |
| | APZ42_027677 | Peptidase A2 domain-containing protein. (1144 aa) |
| | APZ42_027270 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (248 aa) |
| | APZ42_027254 | DNA topoisomerase 2-binding protein 1. (1369 aa) |
| | APZ42_027291 | DNA polymerase. (1463 aa) |
| | APZ42_027299 | Tudor domain-containing protein 3. (602 aa) |
| | APZ42_025523 | Uncharacterized protein. (1608 aa) |
| | APZ42_025209 | DNA helicase; Belongs to the MCM family. (738 aa) |
| | APZ42_024502 | Exonuclease 3'-5' domain-containing protein 2; Belongs to the nanos family. (773 aa) |
| | APZ42_023915 | Uncharacterized protein. (938 aa) |
| | APZ42_023583 | DNA helicase RecQ4. (1242 aa) |
| | APZ42_023587 | Origin recognition complex subunit. (417 aa) |
| | APZ42_022104 | Putative Breast cancer type 2 susceptibility protein. (1569 aa) |
| | APZ42_021873 | DNA helicase; Belongs to the MCM family. (811 aa) |
| | APZ42_021373 | DNA repair protein RAD50. (157 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa) |
| | APZ42_021143 | DNA polymerase delta subunit 3. (448 aa) |
| | APZ42_019954 | Cell division control protein 45. (581 aa) |
| | APZ42_019611 | Putative Xeroderma pigmentosum D. (1045 aa) |
| | APZ42_019144 | Serine/threonine-protein kinase GRP. (213 aa) |
| | APZ42_019138 | ATPase_AAA_core domain-containing protein. (897 aa) |
| | APZ42_018837 | Mutator-like protein. (1075 aa) |
| | APZ42_018195 | Putative DNA topoisomerase 2-binding protein 1. (881 aa) |
| | APZ42_018111 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | APZ42_016631 | WD repeat and HMG-box DNA-binding protein 1. (1029 aa) |
| | APZ42_016194 | Uncharacterized protein. (128 aa) |
