(17 nodes) Mixed, incl. tRNA threonylcarbamoyladenosine metabolic process, and Anoctamin network (Daphnia magna)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	APZ42_022153	Coiled-coil domain-containing protein 85A. (530 aa)
	APZ42_011819	TP53-regulating kinase. (221 aa)
	APZ42_026672	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (334 aa)
	APZ42_014548	Anoctamin. (991 aa)
	APZ42_021767	Anoctamin. (457 aa)
	APZ42_030115	Putative Kanadaptin. (429 aa)
	APZ42_027934	Transmembrane protein. (510 aa)
	APZ42_031515	EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family. (168 aa)
	APZ42_014058	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis. (300 aa)
	APZ42_011203	DTW domain-containing protein 1. (132 aa)
	APZ42_000031	DTW domain-containing protein 2. (170 aa)
	APZ42_031230	Putative O-sialoglycoprotein endopeptidase 2. (78 aa)
	APZ42_031218	O-sialoglycoprotein endopeptidase 2. (222 aa)
	APZ42_022936	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (303 aa)
	APZ42_021415	Putative EKC/KEOPS complex subunit LAGE3. (104 aa)
	APZ42_017896	YrdC domain-containing protein. (226 aa)
	APZ42_016951	Anoctamin. (387 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000031	APZ42_011203	A0A164JYW7	A0A162SH06	DTW domain-containing protein 2.	DTW domain-containing protein 1.	0.560
APZ42_000031	APZ42_014058	A0A164JYW7	A0A162Q9T5	DTW domain-containing protein 2.	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	0.560
APZ42_011203	APZ42_000031	A0A162SH06	A0A164JYW7	DTW domain-containing protein 1.	DTW domain-containing protein 2.	0.560
APZ42_011203	APZ42_014058	A0A162SH06	A0A162Q9T5	DTW domain-containing protein 1.	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	0.559
APZ42_011203	APZ42_022153	A0A162SH06	A0A0P4YCZ2	DTW domain-containing protein 1.	Coiled-coil domain-containing protein 85A.	0.572
APZ42_011203	APZ42_022936	A0A162SH06	A0A164VBM1	DTW domain-containing protein 1.	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.	0.497
APZ42_011819	APZ42_014058	A0A0P5FEP4	A0A162Q9T5	TP53-regulating kinase.	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	0.886
APZ42_011819	APZ42_017896	A0A0P5FEP4	A0A164ZE56	TP53-regulating kinase.	YrdC domain-containing protein.	0.582
APZ42_011819	APZ42_021415	A0A0P5FEP4	A0A164WNG0	TP53-regulating kinase.	Putative EKC/KEOPS complex subunit LAGE3.	0.946
APZ42_011819	APZ42_026672	A0A0P5FEP4	A0A0P5ZB64	TP53-regulating kinase.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.998
APZ42_011819	APZ42_031218	A0A0P5FEP4	A0A164N1T7	TP53-regulating kinase.	O-sialoglycoprotein endopeptidase 2.	0.967
APZ42_011819	APZ42_031230	A0A0P5FEP4	A0A164N1R9	TP53-regulating kinase.	Putative O-sialoglycoprotein endopeptidase 2.	0.967
APZ42_011819	APZ42_031515	A0A0P5FEP4	A0A162DBC8	TP53-regulating kinase.	EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family.	0.998
APZ42_014058	APZ42_000031	A0A162Q9T5	A0A164JYW7	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	DTW domain-containing protein 2.	0.560
APZ42_014058	APZ42_011203	A0A162Q9T5	A0A162SH06	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	DTW domain-containing protein 1.	0.559
APZ42_014058	APZ42_011819	A0A162Q9T5	A0A0P5FEP4	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	TP53-regulating kinase.	0.886
APZ42_014058	APZ42_022936	A0A162Q9T5	A0A164VBM1	Probable ribosome biogenesis protein APZ42_014058; Probable pre-rRNA processing protein involved in ribosome biogenesis.	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.	0.586
APZ42_016951	APZ42_021767	A0A165A9A3	A0A162C9P1	Anoctamin.	Anoctamin.	0.948
APZ42_017896	APZ42_011819	A0A164ZE56	A0A0P5FEP4	YrdC domain-containing protein.	TP53-regulating kinase.	0.582
APZ42_017896	APZ42_021415	A0A164ZE56	A0A164WNG0	YrdC domain-containing protein.	Putative EKC/KEOPS complex subunit LAGE3.	0.572