(31 nodes) Mixed, incl. Protein O-linked mannosylation, and Ubiquitin-dependent protein catabolic process via the N-end rule pathway network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	APZ42_012430	Solute carrier family 13 member 4. (608 aa)
	APZ42_015607	N-terminal asparagine amidohydrolase protein. (309 aa)
	APZ42_018255	Tetratricopeptide repeat protein 7A. (863 aa)
	APZ42_020499	Protein-serine/threonine kinase. (419 aa)
	APZ42_014475	Protein O-mannosyl-transferase 1. (807 aa)
	APZ42_023710	Protein O-mannosyl-transferase 1. (730 aa)
	APZ42_013021	Putative Nucleoside diphosphate-linked moiety X motif. (202 aa)
	APZ42_015045	Transmembrane emp24 domain-containing protein; Belongs to the EMP24/GP25L family. (438 aa)
	APZ42_023715	Protein O-mannosyl-transferase 2. (737 aa)
	APZ42_014832	E3 ubiquitin-protein ligase HECTD1. (3106 aa)
	APZ42_015198	Beta-1,4-glucuronyltransferase 1. (544 aa)
	APZ42_015502	Putative G-protein coupled receptor 158. (815 aa)
	APZ42_015503	G-protein-coupled receptor 158. (508 aa)
	EOG090X02H3	EOG090X02H3. (241 aa)
	APZ42_012308	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1433 aa)
	APZ42_012330	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (580 aa)
	APZ42_004558	I'M NOT DEAD yet protein. (109 aa)
	APZ42_001719	I'M NOT DEAD yet protein. (74 aa)
	APZ42_034301	Glutaminyl-peptide cyclotransferase. (340 aa)
	APZ42_033295	G-protein-coupled receptor. (551 aa)
	APZ42_033306	Uncharacterized protein. (120 aa)
	APZ42_030756	Transmembrane protein 5. (401 aa)
	APZ42_030682	Protein N-terminal asparagine amidohydrolase. (343 aa)
	APZ42_026305	I'M NOT DEAD yet protein. (240 aa)
	APZ42_025866	Nt_Gln_amidase domain-containing protein. (142 aa)
	APZ42_024806	Protein EFR3 B. (812 aa)
	APZ42_023957	Glycosyltransferase protein LARGE1. (684 aa)
	APZ42_023704	Protein O-mannosyl-transferase 2. (710 aa)
	APZ42_023404	Putative Hyccin. (214 aa)
	APZ42_023171	Putative Beta-1,4-glucuronyltransferase 1. (590 aa)
	APZ42_018099	Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family. (388 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_004558	APZ42_026305	A0A164GZD6	A0A164SCK4	I'M NOT DEAD yet protein.	I'M NOT DEAD yet protein.	0.536
APZ42_012308	APZ42_012330	A0A162RYI8	A0A162RYM8	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.936
APZ42_012308	APZ42_014832	A0A162RYI8	A0A162NX99	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase HECTD1.	0.565
APZ42_012330	APZ42_012308	A0A162RYM8	A0A162RYI8	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.936
APZ42_012330	APZ42_014832	A0A162RYM8	A0A162NX99	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase HECTD1.	0.565
APZ42_013021	APZ42_015045	A0A0P5V7Z0	A0A0P5XZ56	Putative Nucleoside diphosphate-linked moiety X motif.	Transmembrane emp24 domain-containing protein; Belongs to the EMP24/GP25L family.	0.524
APZ42_013021	APZ42_018255	A0A0P5V7Z0	A0A0P5DUN1	Putative Nucleoside diphosphate-linked moiety X motif.	Tetratricopeptide repeat protein 7A.	0.424
APZ42_013021	APZ42_020499	A0A0P5V7Z0	A0A0P5FS44	Putative Nucleoside diphosphate-linked moiety X motif.	Protein-serine/threonine kinase.	0.681
APZ42_013021	APZ42_023171	A0A0P5V7Z0	A0A164V5W6	Putative Nucleoside diphosphate-linked moiety X motif.	Putative Beta-1,4-glucuronyltransferase 1.	0.416
APZ42_013021	APZ42_023957	A0A0P5V7Z0	A0A164UCF2	Putative Nucleoside diphosphate-linked moiety X motif.	Glycosyltransferase protein LARGE1.	0.571
APZ42_013021	APZ42_025866	A0A0P5V7Z0	A0A164SPH0	Putative Nucleoside diphosphate-linked moiety X motif.	Nt_Gln_amidase domain-containing protein.	0.557
APZ42_013021	APZ42_034301	A0A0P5V7Z0	A0A164K8P2	Putative Nucleoside diphosphate-linked moiety X motif.	Glutaminyl-peptide cyclotransferase.	0.571
APZ42_014475	APZ42_015198	A0A0P5HFP5	A0A162P9A4	Protein O-mannosyl-transferase 1.	Beta-1,4-glucuronyltransferase 1.	0.584
APZ42_014475	APZ42_023704	A0A0P5HFP5	A0A164UR08	Protein O-mannosyl-transferase 1.	Protein O-mannosyl-transferase 2.	0.872
APZ42_014475	APZ42_023710	A0A0P5HFP5	A0A0P5U0B2	Protein O-mannosyl-transferase 1.	Protein O-mannosyl-transferase 1.	0.873
APZ42_014475	APZ42_023715	A0A0P5HFP5	A0A162DGU6	Protein O-mannosyl-transferase 1.	Protein O-mannosyl-transferase 2.	0.870
APZ42_014475	APZ42_023957	A0A0P5HFP5	A0A164UCF2	Protein O-mannosyl-transferase 1.	Glycosyltransferase protein LARGE1.	0.522
APZ42_014475	APZ42_030756	A0A0P5HFP5	A0A164NB09	Protein O-mannosyl-transferase 1.	Transmembrane protein 5.	0.570
APZ42_014832	APZ42_012308	A0A162NX99	A0A162RYI8	E3 ubiquitin-protein ligase HECTD1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.565
APZ42_014832	APZ42_012330	A0A162NX99	A0A162RYM8	E3 ubiquitin-protein ligase HECTD1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.565