(34 nodes) Mixed, incl. Protein neddylation, and Protein deneddylation network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	APZ42_026853	WD and tetratricopeptide repeats protein 1. (682 aa)
	APZ42_019270	Von Hippel-Lindau disease tumor suppressor. (187 aa)
	APZ42_013754	COP9 signalosome complex subunit 5. (341 aa)
	APZ42_013635	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (330 aa)
	APZ42_026495	NEDD8-activating enzyme E1 regulatory subunit. (546 aa)
	APZ42_012041	WD repeat-containing protein 76. (584 aa)
	APZ42_019580	Transcription elongation factor B Polypeptide 1; Belongs to the SKP1 family. (114 aa)
	APZ42_016090	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (247 aa)
	APZ42_011507	COP9 signalosome complex subunit 1. (481 aa)
	APZ42_017804	COP9 signalosome complex subunit 4. (407 aa)
	APZ42_013220	Leucine-rich repeat protein 1. (405 aa)
	APZ42_013608	Protein lethal(2)denticleless. (567 aa)
	APZ42_026608	COP9 signalosome complex subunit 3 protein. (481 aa)
	APZ42_031744	RING-box protein 2. (115 aa)
	APZ42_023584	DDB1-and CUL4-associated factor 11. (569 aa)
	EOG090X08T4	COP9 signalosome complex subunit. (310 aa)
	APZ42_026496	Nedd8-activating enzyme E1 catalytic subunit. (438 aa)
	APZ42_015467	Sentrin-specific protease 8. (206 aa)
	EOG090X0JP1	Transcription elongation factor B polypeptide 2. (120 aa)
	APZ42_011393	COP9 signalosome complex subunit 8. (194 aa)
	APZ42_011041	Nedd8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	APZ42_006544	Cullin-5; Belongs to the cullin family. (104 aa)
	APZ42_006396	Cullin-5; Belongs to the cullin family. (280 aa)
	APZ42_001590	DNA damage-binding protein 1. (70 aa)
	APZ42_032633	RING-box protein 1A. (116 aa)
	APZ42_031955	Cullin-2; Belongs to the cullin family. (754 aa)
	EOG090X04DO	COP9 signalosome complex subunit 2. (446 aa)
	APZ42_030527	Uncharacterized protein. (399 aa)
	APZ42_029035	COP9 signalosome complex subunit 7a. (266 aa)
	APZ42_027881	Ubiquitin-like domain-containing protein. (333 aa)
	APZ42_024911	Cullin-5; Belongs to the cullin family. (496 aa)
	APZ42_021218	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (257 aa)
	APZ42_017261	Cullin-4B; Belongs to the cullin family. (781 aa)
	APZ42_017612	RBR-type E3 ubiquitin transferase. (453 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001590	APZ42_011041	A0A164IVK8	A0A162T4X2	DNA damage-binding protein 1.	Nedd8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.	0.721
APZ42_001590	APZ42_011393	A0A164IVK8	A0A162SMT5	DNA damage-binding protein 1.	COP9 signalosome complex subunit 8.	0.867
APZ42_001590	APZ42_011507	A0A164IVK8	A0A0P5RA23	DNA damage-binding protein 1.	COP9 signalosome complex subunit 1.	0.951
APZ42_001590	APZ42_012041	A0A164IVK8	A0A0P5K982	DNA damage-binding protein 1.	WD repeat-containing protein 76.	0.976
APZ42_001590	APZ42_013608	A0A164IVK8	A0A0P5XY43	DNA damage-binding protein 1.	Protein lethal(2)denticleless.	0.980
APZ42_001590	APZ42_013635	A0A164IVK8	A0A0P5CHX6	DNA damage-binding protein 1.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.656
APZ42_001590	APZ42_013754	A0A164IVK8	A0A0N8D7N5	DNA damage-binding protein 1.	COP9 signalosome complex subunit 5.	0.913
APZ42_001590	APZ42_016090	A0A164IVK8	A0A0P5P6Z1	DNA damage-binding protein 1.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.681
APZ42_001590	APZ42_017261	A0A164IVK8	A0A164ZS10	DNA damage-binding protein 1.	Cullin-4B; Belongs to the cullin family.	0.987
APZ42_001590	APZ42_017804	A0A164IVK8	A0A0P5SRQ1	DNA damage-binding protein 1.	COP9 signalosome complex subunit 4.	0.883
APZ42_001590	APZ42_019580	A0A164IVK8	A0A0P5N527	DNA damage-binding protein 1.	Transcription elongation factor B Polypeptide 1; Belongs to the SKP1 family.	0.457
APZ42_001590	APZ42_021218	A0A164IVK8	A0A164WV97	DNA damage-binding protein 1.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.720
APZ42_001590	APZ42_023584	A0A164IVK8	A0A0P6FC03	DNA damage-binding protein 1.	DDB1-and CUL4-associated factor 11.	0.953
APZ42_001590	APZ42_026495	A0A164IVK8	A0A0P5DZX1	DNA damage-binding protein 1.	NEDD8-activating enzyme E1 regulatory subunit.	0.708
APZ42_001590	APZ42_026496	A0A164IVK8	A0A162DB39	DNA damage-binding protein 1.	Nedd8-activating enzyme E1 catalytic subunit.	0.705
APZ42_001590	APZ42_026608	A0A164IVK8	A0A0P5Y2J5	DNA damage-binding protein 1.	COP9 signalosome complex subunit 3 protein.	0.869
APZ42_001590	APZ42_026853	A0A164IVK8	A0A0N7ZM69	DNA damage-binding protein 1.	WD and tetratricopeptide repeats protein 1.	0.970
APZ42_001590	APZ42_027881	A0A164IVK8	A0A164QZP1	DNA damage-binding protein 1.	Ubiquitin-like domain-containing protein.	0.881
APZ42_001590	APZ42_029035	A0A164IVK8	A0A164PZ43	DNA damage-binding protein 1.	COP9 signalosome complex subunit 7a.	0.785
APZ42_001590	APZ42_031744	A0A164IVK8	A0A0P6BUL0	DNA damage-binding protein 1.	RING-box protein 2.	0.919