(39 nodes) Mixed, incl. ERAD pathway, and UBX domain network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_011342	E3 ubiquitin-protein ligase RNF139. (684 aa)
	APZ42_017153	Ataxin 3 variant ref. (325 aa)
	APZ42_029534	Putative Ubiquitin conjugation factor E4 A. (1068 aa)
	APZ42_028966	UBX domain-containing protein 4. (453 aa)
	APZ42_021695	Ubiquitin thioesterase OTU1. (311 aa)
	EOG090X03TK	E3 ubiquitin-protein ligase synoviolin. (569 aa)
	APZ42_025760	Spermatogenesis-associated 5 protein 1-like protein. (808 aa)
	APZ42_029247	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (253 aa)
	APZ42_031953	Endoplasmic reticulum lectin 1. (537 aa)
	APZ42_020232	Spermatogenesis-associated protein 5 protein 1. (705 aa)
	APZ42_030898	Cytochrome c oxidase assembly factor 7. (216 aa)
	APZ42_016086	Sel-1. (778 aa)
	APZ42_020501	UBX domain-containing protein 6. (432 aa)
	APZ42_023581	FAS-associated factor 1. (665 aa)
	APZ42_016494	UBX domain-containing protein 1. (317 aa)
	APZ42_013628	Fidgetin protein 1; Belongs to the AAA ATPase family. (618 aa)
	APZ42_029250	Uncharacterized protein. (417 aa)
	APZ42_014101	Pachytene checkpoint protein 2; Belongs to the AAA ATPase family. (418 aa)
	APZ42_032869	UBX domain-containing protein 7. (477 aa)
	APZ42_028072	NSFL1 cofactor p47. (374 aa)
	APZ42_015793	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (261 aa)
	APZ42_013800	Erlin-1. (329 aa)
	APZ42_012975	Ubiquitin conjugation factor E4 A. (982 aa)
	APZ42_011458	BTB/POZ domain-containing protein. (656 aa)
	APZ42_008911	Ubiquitin fusion degradation protein 1. (122 aa)
	APZ42_000771	Ubiquitin fusion degradation protein 1. (86 aa)
	APZ42_034336	Ubiquitin-associated domain-containing protein 2. (358 aa)
	APZ42_034075	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family. (779 aa)
	APZ42_032466	Ubiquitin 7-like protein. (400 aa)
	APZ42_030315	E3 ubiquitin-protein ligase RNF185. (191 aa)
	APZ42_028169	RING finger protein 145. (748 aa)
	APZ42_026192	Nuclear protein localization protein 4. (622 aa)
	APZ42_025808	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein. (309 aa)
	EOG090X06HD	Peptide-N-asparagine amidase. (492 aa)
	APZ42_024318	Tether containing UBX domain for GLUT4. (435 aa)
	APZ42_022982	FAS-associated factor 2-B. (466 aa)
	APZ42_022229	Phospholipase A-2-activating protein. (784 aa)
	APZ42_018430	Uncharacterized protein. (644 aa)
	APZ42_017198	Nuclear valosin-containing protein. (889 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000771	APZ42_011342	A0A164JE78	A0A0P5DXJ9	Ubiquitin fusion degradation protein 1.	E3 ubiquitin-protein ligase RNF139.	0.490
APZ42_000771	APZ42_012975	A0A164JE78	A0A162RAS4	Ubiquitin fusion degradation protein 1.	Ubiquitin conjugation factor E4 A.	0.903
APZ42_000771	APZ42_013628	A0A164JE78	A0A0P5ZTB2	Ubiquitin fusion degradation protein 1.	Fidgetin protein 1; Belongs to the AAA ATPase family.	0.787
APZ42_000771	APZ42_014101	A0A164JE78	A0A0P6G1C5	Ubiquitin fusion degradation protein 1.	Pachytene checkpoint protein 2; Belongs to the AAA ATPase family.	0.787
APZ42_000771	APZ42_015793	A0A164JE78	A0A162NB43	Ubiquitin fusion degradation protein 1.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.948
APZ42_000771	APZ42_016086	A0A164JE78	A0A0P5Z7N7	Ubiquitin fusion degradation protein 1.	Sel-1.	0.424
APZ42_000771	APZ42_016494	A0A164JE78	A0A0P5ZSV9	Ubiquitin fusion degradation protein 1.	UBX domain-containing protein 1.	0.596
APZ42_000771	APZ42_017198	A0A164JE78	A0A164ZR26	Ubiquitin fusion degradation protein 1.	Nuclear valosin-containing protein.	0.787
APZ42_000771	APZ42_020232	A0A164JE78	A0A0P5WCT2	Ubiquitin fusion degradation protein 1.	Spermatogenesis-associated protein 5 protein 1.	0.963
APZ42_000771	APZ42_020501	A0A164JE78	A0A0P5Z862	Ubiquitin fusion degradation protein 1.	UBX domain-containing protein 6.	0.601
APZ42_000771	APZ42_021695	A0A164JE78	A0A0P5S8Z6	Ubiquitin fusion degradation protein 1.	Ubiquitin thioesterase OTU1.	0.952
APZ42_000771	APZ42_022229	A0A164JE78	A0A164W5U9	Ubiquitin fusion degradation protein 1.	Phospholipase A-2-activating protein.	0.963
APZ42_000771	APZ42_022982	A0A164JE78	A0A164VCX0	Ubiquitin fusion degradation protein 1.	FAS-associated factor 2-B.	0.980
APZ42_000771	APZ42_023581	A0A164JE78	A0A0P5ZCT5	Ubiquitin fusion degradation protein 1.	FAS-associated factor 1.	0.982
APZ42_000771	APZ42_024318	A0A164JE78	A0A164UME8	Ubiquitin fusion degradation protein 1.	Tether containing UBX domain for GLUT4.	0.493
APZ42_000771	APZ42_025760	A0A164JE78	A0A0P5TN74	Ubiquitin fusion degradation protein 1.	Spermatogenesis-associated 5 protein 1-like protein.	0.963
APZ42_000771	APZ42_026192	A0A164JE78	A0A164SEF1	Ubiquitin fusion degradation protein 1.	Nuclear protein localization protein 4.	0.999
APZ42_000771	APZ42_028072	A0A164JE78	A0A162D7N3	Ubiquitin fusion degradation protein 1.	NSFL1 cofactor p47.	0.958
APZ42_000771	APZ42_028169	A0A164JE78	A0A164QJE8	Ubiquitin fusion degradation protein 1.	RING finger protein 145.	0.467
APZ42_000771	APZ42_029247	A0A164JE78	A0A0P5U053	Ubiquitin fusion degradation protein 1.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.960