(37 nodes) Mixed, incl. Nuclear receptor activity, and Regulation of gene expression by Hypoxia-inducible Factor network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_031217	Oxysterols receptor LXR-alpha. (385 aa)
	APZ42_019391	ATP-binding cassette sub-family A member. (2089 aa)
	APZ42_027305	Peroxisome proliferator-activated receptor delta. (722 aa)
	APZ42_010864	Nuclear receptor subfamily 4 group A member. (579 aa)
	APZ42_027303	Retinoid x receptor. (699 aa)
	APZ42_018392	Arginine N-methyltransferase 8 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (364 aa)
	APZ42_020117	Aryl hydrocarbon receptor-interacting protein AIP722. (338 aa)
	APZ42_024580	Retinoid x receptor. (463 aa)
	APZ42_012187	Retinoid x receptor. (402 aa)
	APZ42_032642	Nuclear hormone receptor HR96. (522 aa)
	APZ42_018150	ATP-binding cassette sub-family A member. (1956 aa)
	APZ42_013799	Estrogen-related receptor splice variant. (599 aa)
	DapmaFtz-F1	Nuclear receptor subfamily 6 group A member 1. (777 aa)
	APZ42_022790	Uncharacterized protein. (1061 aa)
	APZ42_031134	Uncharacterized protein. (1044 aa)
	APZ42_015929	Histone-arginine methyltransferase CARMER; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (586 aa)
	APZ42_014763	Bile acid receptor. (657 aa)
	APZ42_013603	Putative Neuronal PAS domain-containing protein. (957 aa)
	APZ42_012948	Putative Hypoxia inducible factor-1 alpha. (440 aa)
	APZ42_003079	Putative ATP-binding cassette sub-family A member 1. (91 aa)
	APZ42_031138	Uncharacterized protein. (315 aa)
	APZ42_031130	Uncharacterized protein. (752 aa)
	APZ42_030165	Uncharacterized protein. (124 aa)
	APZ42_027338	Putative CREB-binding protein. (2063 aa)
	APZ42_027025	CREB-binding-like protein. (545 aa)
	APZ42_022480	BHLH domain-containing protein. (132 aa)
	APZ42_022531	Upstream stimulatory factor 2-like protein. (431 aa)
	APZ42_021359	Transcription factor HNF-4. (544 aa)
	APZ42_020897	Neuronal PAS domain-containing protein. (87 aa)
	APZ42_020564	Single-minded 1-A. (897 aa)
	APZ42_019968	Estrogen receptor beta. (399 aa)
	APZ42_019389	ABC protein, subfamily ABCA. (2282 aa)
	APZ42_016876	Bile acid receptor. (1102 aa)
	APZ42_016264	Uncharacterized protein. (267 aa)
	APZ42_016247	Uncharacterized protein. (789 aa)
	RXR	Retinoic acid receptor RXR-alpha-A. (400 aa)
	DmagArnt2	Aryl hydrocarbone receptor nuclear translocator. (668 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_003079	APZ42_012187	A0A164HUI0	A0A0P5WD63	Putative ATP-binding cassette sub-family A member 1.	Retinoid x receptor.	0.562
APZ42_003079	APZ42_014763	A0A164HUI0	A0A162PLH6	Putative ATP-binding cassette sub-family A member 1.	Bile acid receptor.	0.637
APZ42_003079	APZ42_016876	A0A164HUI0	A0A165A840	Putative ATP-binding cassette sub-family A member 1.	Bile acid receptor.	0.563
APZ42_003079	APZ42_024580	A0A164HUI0	A0A0P5VI40	Putative ATP-binding cassette sub-family A member 1.	Retinoid x receptor.	0.562
APZ42_003079	APZ42_027303	A0A164HUI0	A0A0P5F6Q5	Putative ATP-binding cassette sub-family A member 1.	Retinoid x receptor.	0.562
APZ42_003079	APZ42_027305	A0A164HUI0	A0A0P5CZ96	Putative ATP-binding cassette sub-family A member 1.	Peroxisome proliferator-activated receptor delta.	0.562
APZ42_003079	APZ42_031217	A0A164HUI0	A0A0P4YJK8	Putative ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-alpha.	0.637
APZ42_003079	APZ42_032642	A0A164HUI0	A0A0P5XKS8	Putative ATP-binding cassette sub-family A member 1.	Nuclear hormone receptor HR96.	0.562
APZ42_003079	RXR	A0A164HUI0	A1XQQ1	Putative ATP-binding cassette sub-family A member 1.	Retinoic acid receptor RXR-alpha-A.	0.630
APZ42_010864	APZ42_015929	A0A0P5E5N7	A0A162NGK6	Nuclear receptor subfamily 4 group A member.	Histone-arginine methyltransferase CARMER; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.575
APZ42_010864	APZ42_016876	A0A0P5E5N7	A0A165A840	Nuclear receptor subfamily 4 group A member.	Bile acid receptor.	0.895
APZ42_010864	APZ42_020897	A0A0P5E5N7	A0A164X507	Nuclear receptor subfamily 4 group A member.	Neuronal PAS domain-containing protein.	0.588
APZ42_010864	APZ42_022531	A0A0P5E5N7	A0A164VK34	Nuclear receptor subfamily 4 group A member.	Upstream stimulatory factor 2-like protein.	0.588
APZ42_010864	APZ42_022790	A0A0P5E5N7	A0A162C899	Nuclear receptor subfamily 4 group A member.	Uncharacterized protein.	0.615
APZ42_010864	APZ42_027025	A0A0P5E5N7	A0A164RS38	Nuclear receptor subfamily 4 group A member.	CREB-binding-like protein.	0.615
APZ42_010864	APZ42_027338	A0A0P5E5N7	A0A164RHI9	Nuclear receptor subfamily 4 group A member.	Putative CREB-binding protein.	0.615
APZ42_010864	APZ42_031130	A0A0P5E5N7	A0A164N3C0	Nuclear receptor subfamily 4 group A member.	Uncharacterized protein.	0.760
APZ42_010864	APZ42_031134	A0A0P5E5N7	A0A162DC36	Nuclear receptor subfamily 4 group A member.	Uncharacterized protein.	0.779
APZ42_010864	APZ42_031138	A0A0P5E5N7	A0A164N356	Nuclear receptor subfamily 4 group A member.	Uncharacterized protein.	0.779
APZ42_010864	DapmaFtz-F1	A0A0P5E5N7	A0A0P6F3X0	Nuclear receptor subfamily 4 group A member.	Nuclear receptor subfamily 6 group A member 1.	0.632