(16 nodes) Mixed, incl. Role of ABL in ROBO-SLIT signaling, and Filopodium tip network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_019241	Defective proboscis extension response. (326 aa)
	APZ42_022004	Putative Tyrosine-protein kinase Btk29A. (1513 aa)
	APZ42_015024	Defective proboscis extension response. (341 aa)
	APZ42_031673	Dpr-interacting protein beta. (475 aa)
	APZ42_031696	Wrapper. (485 aa)
	APZ42_026702	Membrane glycoprotein lig-1. (379 aa)
	APZ42_021527	SLIT protein. (152 aa)
	APZ42_012592	Putative Roundabout 2. (1460 aa)
	APZ42_030114	Ena/VASP-like protein. (436 aa)
	APZ42_028159	SLIT protein. (1404 aa)
	APZ42_027688	Putative Roundabout 2. (171 aa)
	APZ42_027668	Putative Roundabout 2. (1361 aa)
	APZ42_026769	Putative Roundabout 2. (967 aa)
	APZ42_021732	Uncharacterized protein. (390 aa)
	APZ42_019029	Neuronal growth regulator 1. (341 aa)
	APZ42_018100	Uncharacterized protein. (1237 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_012592	APZ42_015024	A0A162RP05	A0A0P5DE54	Putative Roundabout 2.	Defective proboscis extension response.	0.541
APZ42_012592	APZ42_018100	A0A162RP05	A0A164ZCF9	Putative Roundabout 2.	Uncharacterized protein.	0.751
APZ42_012592	APZ42_019029	A0A162RP05	A0A164YKR8	Putative Roundabout 2.	Neuronal growth regulator 1.	0.541
APZ42_012592	APZ42_019241	A0A162RP05	A0A0N8AYJ3	Putative Roundabout 2.	Defective proboscis extension response.	0.541
APZ42_012592	APZ42_021527	A0A162RP05	A0A162CA77	Putative Roundabout 2.	SLIT protein.	0.875
APZ42_012592	APZ42_021732	A0A162RP05	A0A164WHE7	Putative Roundabout 2.	Uncharacterized protein.	0.740
APZ42_012592	APZ42_022004	A0A162RP05	A0A0P4WMC5	Putative Roundabout 2.	Putative Tyrosine-protein kinase Btk29A.	0.738
APZ42_012592	APZ42_026702	A0A162RP05	A0A0P5TMB8	Putative Roundabout 2.	Membrane glycoprotein lig-1.	0.740
APZ42_012592	APZ42_028159	A0A162RP05	A0A164QJB4	Putative Roundabout 2.	SLIT protein.	0.879
APZ42_012592	APZ42_030114	A0A162RP05	A0A164P1P3	Putative Roundabout 2.	Ena/VASP-like protein.	0.741
APZ42_012592	APZ42_031673	A0A162RP05	A0A0P5QI56	Putative Roundabout 2.	Dpr-interacting protein beta.	0.541
APZ42_012592	APZ42_031696	A0A162RP05	A0A0P5TKM5	Putative Roundabout 2.	Wrapper.	0.550
APZ42_015024	APZ42_012592	A0A0P5DE54	A0A162RP05	Defective proboscis extension response.	Putative Roundabout 2.	0.541
APZ42_015024	APZ42_019029	A0A0P5DE54	A0A164YKR8	Defective proboscis extension response.	Neuronal growth regulator 1.	0.540
APZ42_015024	APZ42_026769	A0A0P5DE54	A0A164RXD5	Defective proboscis extension response.	Putative Roundabout 2.	0.541
APZ42_015024	APZ42_027668	A0A0P5DE54	A0A164R7E8	Defective proboscis extension response.	Putative Roundabout 2.	0.541
APZ42_015024	APZ42_027688	A0A0P5DE54	A0A164R7A9	Defective proboscis extension response.	Putative Roundabout 2.	0.541
APZ42_015024	APZ42_031673	A0A0P5DE54	A0A0P5QI56	Defective proboscis extension response.	Dpr-interacting protein beta.	0.462
APZ42_018100	APZ42_012592	A0A164ZCF9	A0A162RP05	Uncharacterized protein.	Putative Roundabout 2.	0.751
APZ42_018100	APZ42_022004	A0A164ZCF9	A0A0P4WMC5	Uncharacterized protein.	Putative Tyrosine-protein kinase Btk29A.	0.609