(35 nodes) Endoplasmic reticulum organization network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	APZ42_032822	Atlastin-3. (536 aa)
	EOG090X0K7I	Protein Asterix. (111 aa)
	APZ42_023261	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	APZ42_026290	ER membrane protein complex subunit 1. (922 aa)
	APZ42_027184	Protein LSM14 B. (573 aa)
	APZ42_028258	Vesicle transport protein SEC20. (208 aa)
	APZ42_033286	Protein transport protein Sec24C. (1058 aa)
	APZ42_033981	Protein jagunal. (194 aa)
	APZ42_034075	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family. (779 aa)
	APZ42_006122	Putative UPF0428 protein CXorf56. (62 aa)
	APZ42_011695	Ubiquitin protein 4A. (133 aa)
	APZ42_011545	Protein transport Sec16A-like protein. (2112 aa)
	APZ42_012107	Transmembrane protein 170A. (103 aa)
	APZ42_012674	Tryptophan-rich protein. (160 aa)
	APZ42_012858	ADP-ribosylation factor 6-interacting protein 1-like protein. (205 aa)
	APZ42_013114	UPF0428 protein CXorf56. (220 aa)
	APZ42_013667	Golgi to ER traffic protein 4. (388 aa)
	EOG090X0GNX	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (172 aa)
	APZ42_019396	Transport protein Sec31A. (1244 aa)
	APZ42_016541	Pecanex protein 1. (2363 aa)
	APZ42_004446	Receptor expression-enhancing protein. (189 aa)
	APZ42_000521	DNA-directed RNA polymerase II subunit. (268 aa)
	APZ42_011577	Lectin, mannose-binding, 1. (521 aa)
	EOG090X08QZ	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (337 aa)
	APZ42_032447	Putative Basigin. (359 aa)
	APZ42_024204	ER membrane protein complex subunit. (228 aa)
	APZ42_033125	ER membrane protein complex subunit. (218 aa)
	APZ42_030563	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (803 aa)
	APZ42_024119	Transmembrane protein 33. (290 aa)
	APZ42_028784	Vesicular integral-membrane protein VIP36. (321 aa)
	APZ42_015499	Protein lunapark. (419 aa)
	APZ42_011815	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (476 aa)
	APZ42_019318	Dolichyl-phosphate beta-glucosyltransferase. (103 aa)
	APZ42_019901	Synaptotagmin 2 variant 2-like protein. (911 aa)
	APZ42_020982	Miniature spindles-like protein. (1145 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_004446	APZ42_015499	A0A0P5Z508	A0A0N8CIQ7	Receptor expression-enhancing protein.	Protein lunapark.	0.421
APZ42_004446	APZ42_032822	A0A0P5Z508	A0A0P5XZQ8	Receptor expression-enhancing protein.	Atlastin-3.	0.518
APZ42_011545	APZ42_011577	A0A162SSN7	A0A0P5TKR5	Protein transport Sec16A-like protein.	Lectin, mannose-binding, 1.	0.822
APZ42_011545	APZ42_019396	A0A162SSN7	A0A0P5ZWL8	Protein transport Sec16A-like protein.	Transport protein Sec31A.	0.953
APZ42_011545	APZ42_023261	A0A162SSN7	A0A164V2T5	Protein transport Sec16A-like protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.938
APZ42_011545	APZ42_028784	A0A162SSN7	A0A0P4ZPL0	Protein transport Sec16A-like protein.	Vesicular integral-membrane protein VIP36.	0.668
APZ42_011545	APZ42_030563	A0A162SSN7	A0A0P5E3T1	Protein transport Sec16A-like protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.993
APZ42_011545	APZ42_033286	A0A162SSN7	A0A164L8C2	Protein transport Sec16A-like protein.	Protein transport protein Sec24C.	0.990
APZ42_011577	APZ42_011545	A0A0P5TKR5	A0A162SSN7	Lectin, mannose-binding, 1.	Protein transport Sec16A-like protein.	0.822
APZ42_011577	APZ42_019396	A0A0P5TKR5	A0A0P5ZWL8	Lectin, mannose-binding, 1.	Transport protein Sec31A.	0.845
APZ42_011577	APZ42_023261	A0A0P5TKR5	A0A164V2T5	Lectin, mannose-binding, 1.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.822
APZ42_011577	APZ42_028784	A0A0P5TKR5	A0A0P4ZPL0	Lectin, mannose-binding, 1.	Vesicular integral-membrane protein VIP36.	0.750
APZ42_011577	APZ42_030563	A0A0P5TKR5	A0A0P5E3T1	Lectin, mannose-binding, 1.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.856
APZ42_011577	APZ42_033286	A0A0P5TKR5	A0A164L8C2	Lectin, mannose-binding, 1.	Protein transport protein Sec24C.	0.791
APZ42_011577	APZ42_034075	A0A0P5TKR5	A0A164KGP3	Lectin, mannose-binding, 1.	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family.	0.583
APZ42_011695	APZ42_012674	A0A162SWQ0	A0A162RKQ0	Ubiquitin protein 4A.	Tryptophan-rich protein.	0.510
APZ42_011695	APZ42_012858	A0A162SWQ0	A0A162REJ1	Ubiquitin protein 4A.	ADP-ribosylation factor 6-interacting protein 1-like protein.	0.884
APZ42_011695	APZ42_013667	A0A162SWQ0	A0A162QQC2	Ubiquitin protein 4A.	Golgi to ER traffic protein 4.	0.923
APZ42_011695	APZ42_034075	A0A162SWQ0	A0A164KGP3	Ubiquitin protein 4A.	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family.	0.822
APZ42_011695	EOG090X08QZ	A0A162SWQ0	A0A0P5SVW7	Ubiquitin protein 4A.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.872