(37 nodes) Protein secretion network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_023585	Prolactin regulatory element-binding protein. (417 aa)
	APZ42_018667	Syntaxin-5; Belongs to the syntaxin family. (423 aa)
	APZ42_019950	Transmembrane and coiled-coil domain-containing protein 7. (969 aa)
	APZ42_012670	Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (179 aa)
	APZ42_020162	Putative Dual specificity protein phosphatase 10. (1162 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_015892	Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (403 aa)
	APZ42_015378	Transmembrane emp24 domain-containing protein bai. (205 aa)
	APZ42_014768	Dual specificity protein phosphatase 10. (552 aa)
	APZ42_013174	Ras-related protein Rab-10. (201 aa)
	APZ42_012091	Putative EH domain-binding protein 1. (865 aa)
	APZ42_012243	BTB/POZ and BACK domain-containing protein. (500 aa)
	APZ42_011511	Ras-related protein Rab-2. (212 aa)
	EOG090X0HBC	EOG090X0HBC; Belongs to the synaptobrevin family. (213 aa)
	APZ42_011609	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (515 aa)
	APZ42_010920	Nuclear receptor-binding protein. (552 aa)
	EOG090X048D	Beclin-1-like protein. (441 aa)
	APZ42_033286	Protein transport protein Sec24C. (1058 aa)
	APZ42_017724	Putative cTAGE family member 5. (1716 aa)
	APZ42_019442	Darkener of apricot-like protein; Belongs to the protein kinase superfamily. (400 aa)
	APZ42_021699	Transport and Golgi organization protein 2. (290 aa)
	APZ42_023261	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	EOG090X03RP	Pleiotropic regulator 1. (473 aa)
	APZ42_025547	Protein kish; Involved in the early part of the secretory pathway. (71 aa)
	APZ42_028261	Opossum. (245 aa)
	APZ42_028573	Trafficking protein particle complex subunit 11. (1111 aa)
	APZ42_029493	c-Myc promoter-binding protein. (1859 aa)
	APZ42_020965	Ras-related protein Rab-1A. (203 aa)
	EOG090X08OG	Transport and Golgi organization protein 11. (226 aa)
	APZ42_016443	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1. (1907 aa)
	APZ42_016945	Golgi apparatus membrane protein TVP23 homolog. (216 aa)
	APZ42_026739	Vesicle transport protein USE1. (273 aa)
	APZ42_013393	Solute carrier family 35 member F6. (381 aa)
	APZ42_012420	Ras-related protein Rab-8A. (211 aa)
	APZ42_018524	60S ribosomal export protein NMD3. (541 aa)
	APZ42_018794	Sorting nexin-19. (968 aa)
	APZ42_014412	Serine O-palmitoleoyltransferase porcupine; Belongs to the membrane-bound acyltransferase family. (476 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_011511	APZ42_011609	A0A162SRZ7	A0A162SUV1	Ras-related protein Rab-2.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.539
APZ42_011511	APZ42_012420	A0A162SRZ7	A0A0P5R8P7	Ras-related protein Rab-2.	Ras-related protein Rab-8A.	0.773
APZ42_011511	APZ42_013174	A0A162SRZ7	A0A162R329	Ras-related protein Rab-2.	Ras-related protein Rab-10.	0.772
APZ42_011511	APZ42_015378	A0A162SRZ7	A0A162PFE3	Ras-related protein Rab-2.	Transmembrane emp24 domain-containing protein bai.	0.467
APZ42_011511	APZ42_016443	A0A162SRZ7	A0A165AFB9	Ras-related protein Rab-2.	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1.	0.586
APZ42_011511	APZ42_020965	A0A162SRZ7	A0A0N8CTE8	Ras-related protein Rab-2.	Ras-related protein Rab-1A.	0.678
APZ42_011511	APZ42_025707	A0A162SRZ7	A0A162DCJ0	Ras-related protein Rab-2.	Uncharacterized protein.	0.646
APZ42_011511	EOG090X0HBC	A0A162SRZ7	A0A162SSQ9	Ras-related protein Rab-2.	EOG090X0HBC; Belongs to the synaptobrevin family.	0.596
APZ42_011609	APZ42_011511	A0A162SUV1	A0A162SRZ7	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Ras-related protein Rab-2.	0.539
APZ42_011609	APZ42_015378	A0A162SUV1	A0A162PFE3	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Transmembrane emp24 domain-containing protein bai.	0.962
APZ42_011609	APZ42_016443	A0A162SUV1	A0A165AFB9	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1.	0.714
APZ42_011609	APZ42_018667	A0A162SUV1	A0A0P6A860	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Syntaxin-5; Belongs to the syntaxin family.	0.733
APZ42_011609	APZ42_020965	A0A162SUV1	A0A0N8CTE8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Ras-related protein Rab-1A.	0.760
APZ42_011609	EOG090X0HBC	A0A162SUV1	A0A162SSQ9	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	EOG090X0HBC; Belongs to the synaptobrevin family.	0.847
APZ42_012091	APZ42_012420	A0A162S2M8	A0A0P5R8P7	Putative EH domain-binding protein 1.	Ras-related protein Rab-8A.	0.870
APZ42_012091	APZ42_013174	A0A162S2M8	A0A162R329	Putative EH domain-binding protein 1.	Ras-related protein Rab-10.	0.870
APZ42_012420	APZ42_011511	A0A0P5R8P7	A0A162SRZ7	Ras-related protein Rab-8A.	Ras-related protein Rab-2.	0.773
APZ42_012420	APZ42_012091	A0A0P5R8P7	A0A162S2M8	Ras-related protein Rab-8A.	Putative EH domain-binding protein 1.	0.870
APZ42_012420	APZ42_020965	A0A0P5R8P7	A0A0N8CTE8	Ras-related protein Rab-8A.	Ras-related protein Rab-1A.	0.969
APZ42_012420	APZ42_029493	A0A0P5R8P7	A0A164PM75	Ras-related protein Rab-8A.	c-Myc promoter-binding protein.	0.723