(65 nodes) Regulation of epithelial cell migration network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_016508	Uncharacterized protein. (426 aa)
	APZ42_029764	F-box/WD repeat-containing protein 1A. (510 aa)
	APZ42_022454	Putative Ras and Rab interactor 2. (1320 aa)
	APZ42_015618	Putative E3 ubiquitin-protein ligase CBL-B. (544 aa)
	APZ42_024863	Uncharacterized protein. (468 aa)
	APZ42_015890	Origin recognition complex subunit 3. (707 aa)
	APZ42_011771	WD_REPEATS_REGION domain-containing protein. (493 aa)
	APZ42_012004	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (392 aa)
	APZ42_033838	Tyrosine 3-monooxygenase. (523 aa)
	APZ42_014946	Non-specific serine/threonine protein kinase. (880 aa)
	APZ42_015040	Phosphoinositide phospholipase C. (1294 aa)
	APZ42_022687	Dual specificity mitogen-activated protein kinase kinase. (803 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_020162	Putative Dual specificity protein phosphatase 10. (1162 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_032885	F-box domain-containing protein. (183 aa)
	APZ42_016059	Hindsight transcription factor-like protein. (1512 aa)
	APZ42_016148	Uncharacterized protein. (428 aa)
	APZ42_015347	Protein virilizer. (2147 aa)
	APZ42_014768	Dual specificity protein phosphatase 10. (552 aa)
	APZ42_013831	Non-specific serine/threonine protein kinase. (532 aa)
	APZ42_013130	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family. (1116 aa)
	APZ42_013134	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family. (658 aa)
	APZ42_012034	Putative GTP cyclohydrolase I protein punch. (232 aa)
	APZ42_011281	Zinc transporter ZIP13. (441 aa)
	APZ42_011797	Putative DAZ-associated protein 1. (461 aa)
	APZ42_004354	Putative CCAAT/enhancer-binding protein epsilon. (219 aa)
	APZ42_002734	Pro-neuregulin-2, membrane-bound. (63 aa)
	APZ42_002063	Putative Arylsulfatase J. (162 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_034408	Bone morphogenetic protein 8A. (419 aa)
	APZ42_034127	Neuroligin-4. (973 aa)
	APZ42_032195	Pro-neuregulin-2, membrane-bound-like protein. (466 aa)
	APZ42_032079	F-box domain-containing protein. (447 aa)
	APZ42_031138	Uncharacterized protein. (315 aa)
	APZ42_030990	Disintegrin and metalloproteinase domain-containing protein. (912 aa)
	APZ42_029781	F-box domain-containing protein. (442 aa)
	APZ42_029345	Tyrosine-protein phosphatase. (813 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_029208	Signal transducing adapter molecule 1. (481 aa)
	APZ42_029026	Keren. (260 aa)
	APZ42_028159	SLIT protein. (1404 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_023578	Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (2046 aa)
	APZ42_023091	Putative Mitogen-activated protein kinase kinase kinase kinase 4. (1001 aa)
	APZ42_023127	Mitogen-activated protein kinase. (401 aa)
	APZ42_022510	Hepatocyte growth factor-regulated tyrosine kinase substrate. (706 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_021349	Paired amphipathic helix protein Sin3b. (1315 aa)
	APZ42_020407	Angio-associated migratory cell protein. (415 aa)
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020171	Phosphoinositide phospholipase C. (748 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)
	APZ42_019402	Putative Derailed 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (906 aa)
	APZ42_018956	Zinc finger and BTB domain-containing 12-like protein. (530 aa)
	APZ42_018557	Protein patched. (1188 aa)
	APZ42_017916	DnaJ subfamily C member 13. (2205 aa)
	APZ42_016618	Mitogen-activated protein kinase kinase kinase kinase 4. (435 aa)
	APZ42_016447	Insulin receptor substrate 1-like protein. (1672 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_013130	A0A164JH90	A0A162R1L1	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_000652	APZ42_013134	A0A164JH90	A0A162R1M2	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_000652	APZ42_015040	A0A164JH90	A0A0P5Y732	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.653
APZ42_000652	APZ42_015618	A0A164JH90	A0A0P5CJL7	Uncharacterized protein.	Putative E3 ubiquitin-protein ligase CBL-B.	0.596
APZ42_000652	APZ42_019402	A0A164JH90	A0A164Y575	Uncharacterized protein.	Putative Derailed 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.538
APZ42_000652	APZ42_020171	A0A164JH90	A0A164Y277	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.653
APZ42_002063	APZ42_034127	A0A164IJE6	A0A164KGR1	Putative Arylsulfatase J.	Neuroligin-4.	0.465
APZ42_002734	APZ42_013130	A0A164I2R4	A0A162R1L1	Pro-neuregulin-2, membrane-bound.	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	0.577
APZ42_002734	APZ42_013134	A0A164I2R4	A0A162R1M2	Pro-neuregulin-2, membrane-bound.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family.	0.577
APZ42_002734	APZ42_029026	A0A164I2R4	A0A164PZD7	Pro-neuregulin-2, membrane-bound.	Keren.	0.460
APZ42_004354	APZ42_019402	A0A164H432	A0A164Y575	Putative CCAAT/enhancer-binding protein epsilon.	Putative Derailed 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.460
APZ42_011797	APZ42_029026	A0A162T140	A0A164PZD7	Putative DAZ-associated protein 1.	Keren.	0.545
APZ42_012034	APZ42_033838	A0A162S272	A0A0P5VQ30	Putative GTP cyclohydrolase I protein punch.	Tyrosine 3-monooxygenase.	0.689
APZ42_013130	APZ42_000652	A0A162R1L1	A0A164JH90	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.607
APZ42_013130	APZ42_002734	A0A162R1L1	A0A164I2R4	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Pro-neuregulin-2, membrane-bound.	0.577
APZ42_013130	APZ42_013831	A0A162R1L1	A0A162QGI2	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Non-specific serine/threonine protein kinase.	0.899
APZ42_013130	APZ42_014768	A0A162R1L1	A0A162PKT5	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Dual specificity protein phosphatase 10.	0.608
APZ42_013130	APZ42_015040	A0A162R1L1	A0A0P5Y732	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.857
APZ42_013130	APZ42_015618	A0A162R1L1	A0A0P5CJL7	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Putative E3 ubiquitin-protein ligase CBL-B.	0.767
APZ42_013130	APZ42_016447	A0A162R1L1	A0A165AFH6	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Insulin receptor substrate 1-like protein.	0.910