(97 nodes) Regulation of cell morphogenesis network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_009912	Wiskott-Aldrich Syndrome protein. (178 aa)
	APZ42_020558	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (416 aa)
	APZ42_019000	Putative Wiskott-Aldrich syndrome family protein member 3. (748 aa)
	APZ42_010901	Abl interactor. (458 aa)
	APZ42_026249	GNA12/13 guanine nucleotide binding protein, alpha 12/13. (365 aa)
	APZ42_022004	Putative Tyrosine-protein kinase Btk29A. (1513 aa)
	APZ42_005047	ATP-dependent RNA Helicase me31b. (121 aa)
	APZ42_004793	Uncharacterized protein. (299 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_003890	ATP-dependent RNA Helicase me31b. (92 aa)
	APZ42_003266	Rap guanine nucleotide exchange factor 6. (42 aa)
	APZ42_023091	Putative Mitogen-activated protein kinase kinase kinase kinase 4. (1001 aa)
	APZ42_020222	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	APZ42_013520	Sptzle 1B. (218 aa)
	APZ42_033286	Protein transport protein Sec24C. (1058 aa)
	APZ42_031732	Tyrosine-protein kinase. (733 aa)
	APZ42_030789	Ras-related protein Rap-1B. (131 aa)
	APZ42_030841	Uncharacterized protein. (726 aa)
	APZ42_029678	Cytoplasmic FMR1-interacting protein 2. (4712 aa)
	APZ42_028403	Plexin-A4. (1539 aa)
	EOG090X020Y	PR domain zinc finger 12-like protein. (875 aa)
	APZ42_027909	EF-hand domain-containing protein. (527 aa)
	APZ42_027631	Uncharacterized protein. (1702 aa)
	APZ42_027135	Protein vav-like protein. (1151 aa)
	APZ42_027139	Putative Rho guanine nucleotide exchange factor. (808 aa)
	APZ42_026680	ATP-dependent RNA Helicase me31b; Belongs to the DEAD box helicase family. (303 aa)
	APZ42_026441	Adenylyl cyclase-associated protein; Belongs to the CAP family. (480 aa)
	APZ42_025821	Bromo domain-containing protein. (683 aa)
	APZ42_025310	Uncharacterized protein. (661 aa)
	APZ42_024847	Uncharacterized protein. (701 aa)
	APZ42_024024	Bric-a-brac. (562 aa)
	APZ42_023394	Plexin-A4. (462 aa)
	APZ42_023261	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	APZ42_022370	Formin protein. (1071 aa)
	APZ42_012031	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (259 aa)
	APZ42_023822	Serine/threonine-protein kinase LATS1. (1138 aa)
	APZ42_016047	Clip-domain serine protease. (1096 aa)
	APZ42_020441	Caprin-1. (617 aa)
	APZ42_030563	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (803 aa)
	APZ42_017329	Nuclear distribution protein nudE 1-B. (307 aa)
	APZ42_012797	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (867 aa)
	APZ42_018598	LIM domain-containing protein. (342 aa)
	EOG090X0ON0	Protein BRICK1-B. (74 aa)
	EOG090X0FA0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_012906	ATP-dependent RNA Helicase me31b; Belongs to the DEAD box helicase family. (450 aa)
	APZ42_032865	Integrin beta; Belongs to the integrin beta chain family. (810 aa)
	APZ42_019129	Membrane-associated protein Hem. (1120 aa)
	APZ42_003083	BMP and activin membrane-bound inhibitor. (204 aa)
	APZ42_012229	Ras-related protein Rab-11A. (215 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_024020	Uncharacterized protein. (943 aa)
	APZ42_014363	Integrin beta; Belongs to the integrin beta chain family. (614 aa)
	APZ42_015601	Plexin-A4. (271 aa)
	APZ42_015191	Rho-related BTB domain-containing protein 2. (718 aa)
	APZ42_014594	Rap guanine nucleotide exchange factor 6. (1581 aa)
	APZ42_022006	Wd repeat domain-containing-like protein. (1218 aa)
	APZ42_022001	Uncharacterized protein. (1211 aa)
	APZ42_022191	Putative Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (610 aa)
	APZ42_022231	CortBP2 domain-containing protein. (704 aa)
	APZ42_021300	Dusky-like protein. (613 aa)
	APZ42_021013	Uncharacterized protein. (799 aa)
	APZ42_020568	Tyrosine-protein kinase. (587 aa)
	APZ42_020835	Plexin-A4. (1213 aa)
	APZ42_020849	Plexin-A4. (140 aa)
	APZ42_019728	Rho-associated protein kinase 2. (1082 aa)
	APZ42_020194	Putative Osteoclast-stimulating factor 1. (187 aa)
	APZ42_019405	Histone-lysine N-methyltransferase EHMT1. (1097 aa)
	APZ42_018949	Integrin beta; Belongs to the integrin beta chain family. (786 aa)
	APZ42_018956	Zinc finger and BTB domain-containing 12-like protein. (530 aa)
	APZ42_018049	Putative Wiskott-Aldrich Syndrome protein. (264 aa)
	APZ42_018048	Putative Pleckstrin domain-containing family J member 1. (673 aa)
	APZ42_017846	Bromodomain and WD repeat-containing-like protein. (84 aa)
	APZ42_016618	Mitogen-activated protein kinase kinase kinase kinase 4. (435 aa)
	APZ42_016511	Popeye domain containing protein. (401 aa)
	APZ42_016548	Protein kinase domain-containing protein. (927 aa)
	APZ42_014478	Putative Bromodomain and WD repeat-containing protein. (2069 aa)
	APZ42_013697	Putative Multiple wing hairs protein. (948 aa)
	APZ42_013700	Synaptotagmin-17. (549 aa)
	APZ42_012806	ZP domain-containing protein. (372 aa)
	EOG090X0AH4	Nuclear migration protein nudC. (320 aa)
	APZ42_012371	Uncharacterized protein. (946 aa)
	APZ42_012186	Tight junction protein ZO-1. (949 aa)
	APZ42_011191	Putative Tyrosine-protein kinase Fps85D. (917 aa)
	APZ42_011171	Spastin; Belongs to the AAA ATPase family. (674 aa)
	APZ42_005050	Putative ATP-dependent RNA Helicase me31b. (158 aa)
	APZ42_030255	Integrin beta; Belongs to the integrin beta chain family. (791 aa)
	APZ42_020417	Kinase c and casein kinase substrate in neurons protein. (534 aa)
	APZ42_011032	Zona pellucida domain-containing protein. (638 aa)
	APZ42_019011	ECT2 protein. (898 aa)
	APZ42_014248	Ras-related protein Rab-35. (201 aa)
	APZ42_013628	Fidgetin protein 1; Belongs to the AAA ATPase family. (618 aa)
	APZ42_011520	Kelch domain-containing protein 2. (654 aa)
	APZ42_016103	Putative Cadherin-86C. (1281 aa)
	APZ42_002599	Plexin-A4. (425 aa)
	APZ42_000871	Rho-associated protein kinase 2. (107 aa)
	APZ42_034100	Wiskott-Aldrich Syndrome family protein member. (143 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000871	APZ42_002599	A0A164JBM9	A0A164I614	Rho-associated protein kinase 2.	Plexin-A4.	0.491
APZ42_000871	APZ42_004669	A0A164JBM9	A0A164GWT3	Rho-associated protein kinase 2.	Ras GTP-binding protein Rho1.	0.868
APZ42_000871	APZ42_012031	A0A164JBM9	A0A0P4YC34	Rho-associated protein kinase 2.	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	0.486
APZ42_000871	APZ42_012186	A0A164JBM9	A0A162S7V1	Rho-associated protein kinase 2.	Tight junction protein ZO-1.	0.579
APZ42_000871	APZ42_012615	A0A164JBM9	A0A0P5KP21	Rho-associated protein kinase 2.	Rho-related GTP-binding protein RhoF.	0.868
APZ42_000871	APZ42_014363	A0A164JBM9	A0A162EJD3	Rho-associated protein kinase 2.	Integrin beta; Belongs to the integrin beta chain family.	0.433
APZ42_000871	APZ42_015191	A0A164JBM9	A0A162P9H3	Rho-associated protein kinase 2.	Rho-related BTB domain-containing protein 2.	0.798
APZ42_000871	APZ42_015601	A0A164JBM9	A0A162NU14	Rho-associated protein kinase 2.	Plexin-A4.	0.491
APZ42_000871	APZ42_018949	A0A164JBM9	A0A164YYE1	Rho-associated protein kinase 2.	Integrin beta; Belongs to the integrin beta chain family.	0.433
APZ42_000871	APZ42_020835	A0A164JBM9	A0A164XFJ3	Rho-associated protein kinase 2.	Plexin-A4.	0.491
APZ42_000871	APZ42_020849	A0A164JBM9	A0A164XFN6	Rho-associated protein kinase 2.	Plexin-A4.	0.491
APZ42_000871	APZ42_022001	A0A164JBM9	A0A164VYV0	Rho-associated protein kinase 2.	Uncharacterized protein.	0.626
APZ42_000871	APZ42_022191	A0A164JBM9	A0A164W4D1	Rho-associated protein kinase 2.	Putative Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2.	0.639
APZ42_000871	APZ42_022370	A0A164JBM9	A0A0P6F0M2	Rho-associated protein kinase 2.	Formin protein.	0.508
APZ42_000871	APZ42_023394	A0A164JBM9	A0A164UZN1	Rho-associated protein kinase 2.	Plexin-A4.	0.491
APZ42_000871	APZ42_025707	A0A164JBM9	A0A162DCJ0	Rho-associated protein kinase 2.	Uncharacterized protein.	0.693
APZ42_000871	APZ42_026249	A0A164JBM9	A0A0N8DNV3	Rho-associated protein kinase 2.	GNA12/13 guanine nucleotide binding protein, alpha 12/13.	0.622
APZ42_000871	APZ42_027135	A0A164JBM9	A0A164RB99	Rho-associated protein kinase 2.	Protein vav-like protein.	0.580
APZ42_000871	APZ42_027139	A0A164JBM9	A0A164RBB5	Rho-associated protein kinase 2.	Putative Rho guanine nucleotide exchange factor.	0.580
APZ42_000871	APZ42_028403	A0A164JBM9	A0A164QIQ8	Rho-associated protein kinase 2.	Plexin-A4.	0.491