(68 nodes) Gland morphogenesis network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_016272	Putative Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (523 aa)
	APZ42_019205	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (130 aa)
	APZ42_019198	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (420 aa)
	APZ42_018960	Nyctalopin. (579 aa)
	APZ42_018366	Uncharacterized protein. (625 aa)
	APZ42_025448	DDB1-and CUL4-associated factor 12. (462 aa)
	APZ42_012090	Tyrosine-protein kinase RYK. (539 aa)
	APZ42_023748	Tyrosine-protein kinase. (537 aa)
	APZ42_011208	Forkhead box Q1-like protein. (561 aa)
	EOG090X0511	Putative Neurogenin-3. (297 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_017990	Exonuclease 3'-5' domain-containing protein. (812 aa)
	APZ42_025681	Tyrosine-protein kinase. (712 aa)
	APZ42_026322	Putative Segment polarity protein dishevelled. (699 aa)
	APZ42_023498	Putative Jelly Belly. (477 aa)
	APZ42_022906	Inositol 1,4,5-trisphosphate receptor type. (2851 aa)
	APZ42_016247	Uncharacterized protein. (789 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_011802	Non-specific serine/threonine protein kinase. (595 aa)
	APZ42_016095	Tyrosine-protein kinase. (524 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_018829	RB1-inducible coiled-coil protein. (1116 aa)
	APZ42_027869	Headcase protein. (284 aa)
	APZ42_026999	Mediator of RNA polymerase II transcription subunit 12 protein. (486 aa)
	APZ42_026239	Caspase Dronc; Belongs to the peptidase C14A family. (466 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_024020	Uncharacterized protein. (943 aa)
	APZ42_026442	Protein crumbs. (2334 aa)
	APZ42_015255	Lysine-specific demethylase 6A. (1264 aa)
	APZ42_015375	BAX inhibitor 1; Belongs to the BI1 family. (244 aa)
	APZ42_014478	Putative Bromodomain and WD repeat-containing protein. (2069 aa)
	APZ42_012371	Uncharacterized protein. (946 aa)
	APZ42_011273	Laminin subunit gamma-3. (1735 aa)
	APZ42_011609	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (515 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_002304	Trachealess protein. (105 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_034215	Uncharacterized protein. (222 aa)
	APZ42_032544	Uncharacterized protein. (3708 aa)
	APZ42_032582	FYVE-type domain-containing protein. (115 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_028675	Eater. (1100 aa)
	APZ42_027909	EF-hand domain-containing protein. (527 aa)
	APZ42_027631	Uncharacterized protein. (1702 aa)
	APZ42_027472	Putative Selenoprotein H. (481 aa)
	APZ42_026582	Mediator of RNA polymerase II transcription subunit 12 protein. (413 aa)
	APZ42_026234	Integrin alpha-PS1; Belongs to the integrin alpha chain family. (999 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_025821	Bromo domain-containing protein. (683 aa)
	APZ42_025771	ETS domain-containing protein. (344 aa)
	APZ42_025326	Kinase; Belongs to the inositol phosphokinase (IPK) family. (667 aa)
	APZ42_024024	Bric-a-brac. (562 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_023360	Simliar to lola-like protein. (129 aa)
	APZ42_022951	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (207 aa)
	APZ42_022686	Dynamin. (531 aa)
	APZ42_022006	Wd repeat domain-containing-like protein. (1218 aa)
	APZ42_022001	Uncharacterized protein. (1211 aa)
	APZ42_021970	Mediator of RNA polymerase II transcription subunit 12 protein. (1175 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_020410	Ribonuclease 3. (1155 aa)
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_004669	A0A164JH90	A0A164GWT3	Uncharacterized protein.	Ras GTP-binding protein Rho1.	0.466
APZ42_000652	APZ42_012615	A0A164JH90	A0A0P5KP21	Uncharacterized protein.	Rho-related GTP-binding protein RhoF.	0.466
APZ42_000652	APZ42_016095	A0A164JH90	A0A0P6H5F8	Uncharacterized protein.	Tyrosine-protein kinase.	0.588
APZ42_000652	APZ42_023748	A0A164JH90	A0A0N8DE06	Uncharacterized protein.	Tyrosine-protein kinase.	0.588
APZ42_000652	APZ42_026322	A0A164JH90	A0A0P5YKA8	Uncharacterized protein.	Putative Segment polarity protein dishevelled.	0.419
APZ42_004669	APZ42_000652	A0A164GWT3	A0A164JH90	Ras GTP-binding protein Rho1.	Uncharacterized protein.	0.466
APZ42_004669	APZ42_011609	A0A164GWT3	A0A162SUV1	Ras GTP-binding protein Rho1.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.539
APZ42_004669	APZ42_011802	A0A164GWT3	A0A0P6EQN6	Ras GTP-binding protein Rho1.	Non-specific serine/threonine protein kinase.	0.837
APZ42_004669	APZ42_016095	A0A164GWT3	A0A0P6H5F8	Ras GTP-binding protein Rho1.	Tyrosine-protein kinase.	0.704
APZ42_004669	APZ42_019921	A0A164GWT3	A0A162CDQ9	Ras GTP-binding protein Rho1.	Protein kinase domain-containing protein.	0.466
APZ42_004669	APZ42_019958	A0A164GWT3	A0A162CMM2	Ras GTP-binding protein Rho1.	Uncharacterized protein.	0.466
APZ42_004669	APZ42_020054	A0A164GWT3	A0A164XZF9	Ras GTP-binding protein Rho1.	Putative Vascular endothelial growth factor receptor 3.	0.466
APZ42_004669	APZ42_020116	A0A164GWT3	A0A164Y0N9	Ras GTP-binding protein Rho1.	Putative Receptor-type tyrosine-protein kinase FLT3.	0.466
APZ42_004669	APZ42_020123	A0A164GWT3	A0A164Y074	Ras GTP-binding protein Rho1.	Protein kinase domain-containing protein.	0.466
APZ42_004669	APZ42_020156	A0A164GWT3	A0A164Y2V3	Ras GTP-binding protein Rho1.	Protein kinase domain-containing protein.	0.466
APZ42_004669	APZ42_020161	A0A164GWT3	A0A164Y2T4	Ras GTP-binding protein Rho1.	Putative Vascular endothelial growth factor receptor 1.	0.466
APZ42_004669	APZ42_020225	A0A164GWT3	A0A164Y3U6	Ras GTP-binding protein Rho1.	Receptor protein-tyrosine kinase.	0.466
APZ42_004669	APZ42_021685	A0A164GWT3	A0A164WH24	Ras GTP-binding protein Rho1.	Tyrosine-protein kinase JAK1.	0.466
APZ42_004669	APZ42_022951	A0A164GWT3	A0A164VB60	Ras GTP-binding protein Rho1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.642
APZ42_004669	APZ42_023748	A0A164GWT3	A0A0N8DE06	Ras GTP-binding protein Rho1.	Tyrosine-protein kinase.	0.704