(45 nodes) Z disc network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_017757	Putative Fibronectin type-III domain-containing protein 3A. (8101 aa)
	APZ42_024080	Lethal2essential for life protein; Belongs to the small heat shock protein (HSP20) family. (166 aa)
	APZ42_029287	Nhl ring finger b-box coiled coil domain containing family member nhl-3. (714 aa)
	APZ42_021038	Cysteine and glycine-rich protein. (433 aa)
	APZ42_030708	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (309 aa)
	APZ42_012616	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	APZ42_016297	PDZ and LIM domain protein. (441 aa)
	APZ42_024808	Disheveled-associated activator of morphogenesis 2. (1204 aa)
	APZ42_027249	Chondroitin sulfate proteoglycan. (2570 aa)
	EOG090X0BSC	Triosephosphate isomerase. (251 aa)
	APZ42_024085	Lethal2essential for life protein; Belongs to the small heat shock protein (HSP20) family. (170 aa)
	APZ42_012988	E3 ubiquitin-protein ligase mind-bomb. (977 aa)
	APZ42_001738	Titin. (496 aa)
	APZ42_028338	Putative Survival motor neuron protein. (191 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_015735	HEAT shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (222 aa)
	APZ42_015114	Filamin-B. (1510 aa)
	APZ42_015250	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	APZ42_013827	Alpha-actinin, sarcomeric. (895 aa)
	APZ42_011576	Talin-2. (2425 aa)
	APZ42_001860	Uncharacterized protein. (356 aa)
	APZ42_001722	Putative Presenilin. (124 aa)
	APZ42_034018	Uncharacterized protein. (943 aa)
	APZ42_032598	Testin. (962 aa)
	APZ42_032292	Ryanodine receptor. (5136 aa)
	APZ42_032337	PDZ and LIM domain protein 3. (297 aa)
	APZ42_032342	Putative E3 ubiquitin-protein ligase MIB2. (261 aa)
	APZ42_030885	Uncharacterized protein. (1817 aa)
	APZ42_029836	Titin. (975 aa)
	APZ42_029283	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (366 aa)
	APZ42_028737	Jitterbug. (2881 aa)
	APZ42_028091	Uncharacterized protein. (98 aa)
	APZ42_027627	Uncharacterized protein. (10574 aa)
	APZ42_027626	Uncharacterized protein. (4802 aa)
	APZ42_027187	Tripartite motif-containing protein 2. (1563 aa)
	APZ42_027383	Muscleblind 1-like protein. (978 aa)
	APZ42_027436	BAG domain-containing protein. (589 aa)
	APZ42_027032	Putative LIM and SH3 domain protein Lasp. (461 aa)
	APZ42_024772	Putative Z band alternatively spliced PDZ-motif protein. (397 aa)
	APZ42_024019	LIM domain-containing protein 2. (286 aa)
	APZ42_021922	Putative Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein. (184 aa)
	APZ42_021612	ZM domain-containing protein. (209 aa)
	APZ42_021342	Filamin-B. (1034 aa)
	APZ42_019485	Putative Inversin. (3235 aa)
	APZ42_019228	Flightless-1 protein. (1232 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001722	APZ42_032292	A0A164ISJ8	A0A164M377	Putative Presenilin.	Ryanodine receptor.	0.762
APZ42_001738	APZ42_001860	A0A162CZX8	A0A164IPD4	Titin.	Uncharacterized protein.	0.478
APZ42_001738	APZ42_027626	A0A162CZX8	A0A164R668	Titin.	Uncharacterized protein.	0.478
APZ42_001738	APZ42_027627	A0A162CZX8	A0A164R629	Titin.	Uncharacterized protein.	0.478
APZ42_001860	APZ42_001738	A0A164IPD4	A0A162CZX8	Uncharacterized protein.	Titin.	0.478
APZ42_001860	APZ42_011576	A0A164IPD4	A0A162STT1	Uncharacterized protein.	Talin-2.	0.488
APZ42_001860	APZ42_013827	A0A164IPD4	A0A162QG52	Uncharacterized protein.	Alpha-actinin, sarcomeric.	0.793
APZ42_001860	APZ42_017757	A0A164IPD4	A0A164ZLB7	Uncharacterized protein.	Putative Fibronectin type-III domain-containing protein 3A.	0.732
APZ42_001860	APZ42_027626	A0A164IPD4	A0A164R668	Uncharacterized protein.	Uncharacterized protein.	0.899
APZ42_001860	APZ42_029836	A0A164IPD4	A0A164P9X9	Uncharacterized protein.	Titin.	0.945
APZ42_011576	APZ42_001860	A0A162STT1	A0A164IPD4	Talin-2.	Uncharacterized protein.	0.488
APZ42_011576	APZ42_013827	A0A162STT1	A0A162QG52	Talin-2.	Alpha-actinin, sarcomeric.	0.569
APZ42_011576	APZ42_015114	A0A162STT1	A0A162P7G4	Talin-2.	Filamin-B.	0.640
APZ42_011576	APZ42_016297	A0A162STT1	A0A0P5XQ94	Talin-2.	PDZ and LIM domain protein.	0.664
APZ42_011576	APZ42_017757	A0A162STT1	A0A164ZLB7	Talin-2.	Putative Fibronectin type-III domain-containing protein 3A.	0.529
APZ42_011576	APZ42_021342	A0A162STT1	A0A164WRQ5	Talin-2.	Filamin-B.	0.640
APZ42_011576	APZ42_021612	A0A162STT1	A0A164WIN3	Talin-2.	ZM domain-containing protein.	0.664
APZ42_011576	APZ42_024772	A0A162STT1	A0A164TS36	Talin-2.	Putative Z band alternatively spliced PDZ-motif protein.	0.664
APZ42_011576	APZ42_025707	A0A162STT1	A0A162DCJ0	Talin-2.	Uncharacterized protein.	0.474
APZ42_011576	APZ42_027626	A0A162STT1	A0A164R668	Talin-2.	Uncharacterized protein.	0.488