(42 nodes) Actin filament-based movement network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_025082	Putative Myosin-XV. (115 aa)
	APZ42_019728	Rho-associated protein kinase 2. (1082 aa)
	APZ42_020764	Myosin-IB. (305 aa)
	APZ42_020752	Myosin-IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (634 aa)
	APZ42_021013	Uncharacterized protein. (799 aa)
	APZ42_021300	Dusky-like protein. (613 aa)
	APZ42_022323	Myosin 10A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3016 aa)
	APZ42_024017	ASD2 domain-containing protein. (881 aa)
	APZ42_024646	Putative Myosin-XV. (114 aa)
	APZ42_026856	Myosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (943 aa)
	APZ42_027139	Putative Rho guanine nucleotide exchange factor. (808 aa)
	APZ42_027135	Protein vav-like protein. (1151 aa)
	APZ42_027647	Putative Myosin-XV. (102 aa)
	APZ42_028862	Unconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (987 aa)
	APZ42_030481	Putative Poor gastrulation. (716 aa)
	APZ42_030841	Uncharacterized protein. (726 aa)
	APZ42_033777	TNF receptor-associated factor 4. (359 aa)
	APZ42_000871	Rho-associated protein kinase 2. (107 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_011821	Myosin-XV-like protein. (292 aa)
	APZ42_012806	ZP domain-containing protein. (372 aa)
	APZ42_013315	Rho GTPase-activating protein. (456 aa)
	APZ42_014449	Myosin-rhogap protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (513 aa)
	APZ42_004911	Myosin-IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (202 aa)
	APZ42_026442	Protein crumbs. (2334 aa)
	APZ42_024859	Dachs protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1432 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_009912	Wiskott-Aldrich Syndrome protein. (178 aa)
	APZ42_022515	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (566 aa)
	APZ42_015651	Myosin-I heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2141 aa)
	APZ42_024059	Unconventional myosin-XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (899 aa)
	APZ42_011032	Zona pellucida domain-containing protein. (638 aa)
	APZ42_033654	Unconventional myosin-VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1246 aa)
	APZ42_027285	Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2172 aa)
	APZ42_022783	Nonmuscle myosin essential light chain. (147 aa)
	APZ42_033255	Unconventional myosin-Va; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_019397	Unconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1017 aa)
	APZ42_026249	GNA12/13 guanine nucleotide binding protein, alpha 12/13. (365 aa)
	APZ42_017014	Catenin alpha. (953 aa)
	APZ42_018048	Putative Pleckstrin domain-containing family J member 1. (673 aa)
	APZ42_018049	Putative Wiskott-Aldrich Syndrome protein. (264 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000871	APZ42_004669	A0A164JBM9	A0A164GWT3	Rho-associated protein kinase 2.	Ras GTP-binding protein Rho1.	0.868
APZ42_000871	APZ42_012615	A0A164JBM9	A0A0P5KP21	Rho-associated protein kinase 2.	Rho-related GTP-binding protein RhoF.	0.868
APZ42_000871	APZ42_024017	A0A164JBM9	A0A164UDD4	Rho-associated protein kinase 2.	ASD2 domain-containing protein.	0.406
APZ42_000871	APZ42_025707	A0A164JBM9	A0A162DCJ0	Rho-associated protein kinase 2.	Uncharacterized protein.	0.693
APZ42_000871	APZ42_026249	A0A164JBM9	A0A0N8DNV3	Rho-associated protein kinase 2.	GNA12/13 guanine nucleotide binding protein, alpha 12/13.	0.622
APZ42_000871	APZ42_027135	A0A164JBM9	A0A164RB99	Rho-associated protein kinase 2.	Protein vav-like protein.	0.580
APZ42_000871	APZ42_027139	A0A164JBM9	A0A164RBB5	Rho-associated protein kinase 2.	Putative Rho guanine nucleotide exchange factor.	0.580
APZ42_004669	APZ42_000871	A0A164GWT3	A0A164JBM9	Ras GTP-binding protein Rho1.	Rho-associated protein kinase 2.	0.868
APZ42_004669	APZ42_009912	A0A164GWT3	A0A162BQ17	Ras GTP-binding protein Rho1.	Wiskott-Aldrich Syndrome protein.	0.746
APZ42_004669	APZ42_013315	A0A164GWT3	A0A162QW16	Ras GTP-binding protein Rho1.	Rho GTPase-activating protein.	0.761
APZ42_004669	APZ42_017014	A0A164GWT3	A0A165AB65	Ras GTP-binding protein Rho1.	Catenin alpha.	0.495
APZ42_004669	APZ42_018048	A0A164GWT3	A0A164ZIH3	Ras GTP-binding protein Rho1.	Putative Pleckstrin domain-containing family J member 1.	0.746
APZ42_004669	APZ42_018049	A0A164GWT3	A0A164ZIE2	Ras GTP-binding protein Rho1.	Putative Wiskott-Aldrich Syndrome protein.	0.746
APZ42_004669	APZ42_019728	A0A164GWT3	A0A164XP70	Ras GTP-binding protein Rho1.	Rho-associated protein kinase 2.	0.868
APZ42_004669	APZ42_021300	A0A164GWT3	A0A164WSZ8	Ras GTP-binding protein Rho1.	Dusky-like protein.	0.440
APZ42_004669	APZ42_022783	A0A164GWT3	A0A0P5PCD4	Ras GTP-binding protein Rho1.	Nonmuscle myosin essential light chain.	0.691
APZ42_004669	APZ42_024059	A0A164GWT3	A0A0P5ZT33	Ras GTP-binding protein Rho1.	Unconventional myosin-XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.441
APZ42_004669	APZ42_024859	A0A164GWT3	A0A162DE77	Ras GTP-binding protein Rho1.	Dachs protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.441
APZ42_004669	APZ42_025707	A0A164GWT3	A0A162DCJ0	Ras GTP-binding protein Rho1.	Uncharacterized protein.	0.928
APZ42_004669	APZ42_026249	A0A164GWT3	A0A0N8DNV3	Ras GTP-binding protein Rho1.	GNA12/13 guanine nucleotide binding protein, alpha 12/13.	0.814