(27 nodes) Secretory granule network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_028251	GTP-binding protein 2. (605 aa)
	APZ42_019009	Plasma alpha-L-fucosidase; Belongs to the glycosyl hydrolase 29 family. (499 aa)
	APZ42_022906	Inositol 1,4,5-trisphosphate receptor type. (2851 aa)
	APZ42_026207	7,8-dihydro-8-oxoguanine triphosphatase. (157 aa)
	APZ42_020803	DBH monooxygenase 1-like protein. (799 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_029903	Ras-related protein Rab-27A. (223 aa)
	APZ42_022407	DOMON domain-containing protein. (188 aa)
	APZ42_033023	Putative TGF-beta ligand glass bottom boat protein. (459 aa)
	APZ42_001854	Dihydrolipoamide dehydrogenase-like protein. (117 aa)
	APZ42_024201	AP-1 complex subunit gamma. (912 aa)
	APZ42_012149	Plasma alpha-L-fucosidase; Belongs to the glycosyl hydrolase 29 family. (467 aa)
	APZ42_010960	Uncharacterized protein. (695 aa)
	APZ42_018558	Uncharacterized protein. (317 aa)
	APZ42_012229	Ras-related protein Rab-11A. (215 aa)
	APZ42_002221	Dihydrolipoamide dehydrogenase-like protein. (160 aa)
	APZ42_024157	IQ and ubiquitin domain-containing protein. (479 aa)
	APZ42_023165	Syntaxin-binding protein; Belongs to the STXBP/unc-18/SEC1 family. (588 aa)
	APZ42_013485	Sec1 family domain-containing protein. (216 aa)
	APZ42_032515	Synaptotagmin 1 protein, variant 2. (445 aa)
	APZ42_030823	DOMON domain-containing protein. (172 aa)
	APZ42_022951	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (207 aa)
	APZ42_022874	DBH monooxygenase 1-like protein. (636 aa)
	APZ42_021256	Sec1 family domain-containing protein; Belongs to the STXBP/unc-18/SEC1 family. (474 aa)
	APZ42_019864	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (174 aa)
	APZ42_028914	Putative Receptor-type tyrosine-protein phosphatase N2. (940 aa)
	APZ42_016314	DOMON domain-containing protein. (174 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001854	APZ42_002221	A0A164IPI5	A0A162CZ45	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_001854	APZ42_024157	A0A164IPI5	A0A0P5M1L6	Dihydrolipoamide dehydrogenase-like protein.	IQ and ubiquitin domain-containing protein.	0.455
APZ42_002221	APZ42_001854	A0A162CZ45	A0A164IPI5	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_002221	APZ42_024157	A0A162CZ45	A0A0P5M1L6	Dihydrolipoamide dehydrogenase-like protein.	IQ and ubiquitin domain-containing protein.	0.455
APZ42_010960	APZ42_012229	A0A162TCE3	A0A162CY40	Uncharacterized protein.	Ras-related protein Rab-11A.	0.713
APZ42_010960	APZ42_018911	A0A162TCE3	A0A162CQ61	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.564
APZ42_010960	APZ42_022906	A0A162TCE3	A0A0P5ZUN0	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type.	0.518
APZ42_012229	APZ42_010960	A0A162CY40	A0A162TCE3	Ras-related protein Rab-11A.	Uncharacterized protein.	0.713
APZ42_012229	APZ42_018911	A0A162CY40	A0A162CQ61	Ras-related protein Rab-11A.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.739
APZ42_012229	APZ42_019864	A0A162CY40	A0A164XT43	Ras-related protein Rab-11A.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.418
APZ42_012229	APZ42_022951	A0A162CY40	A0A164VB60	Ras-related protein Rab-11A.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.466
APZ42_012229	APZ42_024201	A0A162CY40	A0A0P5LLS2	Ras-related protein Rab-11A.	AP-1 complex subunit gamma.	0.656
APZ42_012229	APZ42_029903	A0A162CY40	A0A0N8E224	Ras-related protein Rab-11A.	Ras-related protein Rab-27A.	0.781
APZ42_012229	APZ42_032515	A0A162CY40	A0A164LM42	Ras-related protein Rab-11A.	Synaptotagmin 1 protein, variant 2.	0.453
APZ42_013485	APZ42_021256	A0A162QU17	A0A164WU40	Sec1 family domain-containing protein.	Sec1 family domain-containing protein; Belongs to the STXBP/unc-18/SEC1 family.	0.505
APZ42_018911	APZ42_010960	A0A162CQ61	A0A162TCE3	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.564
APZ42_018911	APZ42_012229	A0A162CQ61	A0A162CY40	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Ras-related protein Rab-11A.	0.739
APZ42_018911	APZ42_019864	A0A162CQ61	A0A164XT43	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.434
APZ42_018911	APZ42_022951	A0A162CQ61	A0A164VB60	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.476
APZ42_018911	APZ42_024201	A0A162CQ61	A0A0P5LLS2	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-1 complex subunit gamma.	0.986